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Uglevodnyy Obmen Pri Eksperimental'nom Alkogolizme
ISBN: 9783659415531 / Rosyjski / Miękka / 76 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Zloupotreblenie alkogolem soprovozhdaetsya narusheniem uglevodnogo obmena i yavlyaetsya faktorom riska sakharnogo diabeta. Diabetogennye effekty alkogolya vklyuchayut neposredstvennoe toksicheskoe vozdeystvie na kletki podzheludochnoy zhelezy, ingibirovanie sekretsii insulina i povyshenie rezistentnosti k nemu, narushenie uglevodnogo obmena, ozhirenie, obuslovlennoe postupleniem izlishnikh kaloriy, a takzhe narushenie funktsiy pecheni. Nastoyashchaya monografiya posvyashchena sostoyaniyu uglevodnogo obmena pri razlichnykh rezhimakh eksperimental'noy alkogol'noy intoksikatsii. Obsuzhdaetsya...
Zloupotreblenie alkogolem soprovozhdaetsya narusheniem uglevodnogo obmena i yavlyaetsya faktorom riska sakharnogo diabeta. Diabetogennye effekty alkog...
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Challenges in Isolation of Full Length Vacuolating Cytotoxin Vaca
ISBN: 9783659401305 / Angielski / Miękka / 52 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. |
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Osobennosti Kinetiki Bifunktsional'noy Dnk-Metiltransferazy M.Ecl18ki
ISBN: 9783659413148 / Rosyjski / Miękka / 56 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. V dannoy rabote privoditsya kratkiy obzor mirovoy literatury po strukture i funktsionirovaniyu DNK-metiltransferaz. Krome togo, predstavleny dannye po izucheniyu kineticheskikh svoystv bifunktsionalnoy DNK-metiltransferazy II tipa Ecl18kI. Iskhodya iz nachalnykh skorostey reaktsiy v zavisimosti ot S-adenozil-L-metionina (AdoMet) i substratnoy DNK predlozhen mekhanizm deystviya fermenta. Predpolozhitelno on funktsioniruet po bystroravnovesnomu uporyadochennomu bi bi mekhanizmu so svyazyvaniem metiliruemoy DNK pered svyazyvaniem AdoMet. S pomoshchyu izmereniya aktivnosti fermenta v zavisimosti...
V dannoy rabote privoditsya kratkiy obzor mirovoy literatury po strukture i funktsionirovaniyu DNK-metiltransferaz. Krome togo, predstavleny dannye po...
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Mutational Analysis of P53 Gene and Dietary Risk Factors
ISBN: 9783848499526 / Angielski / Miękka / 52 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Endometrial carcinoma is one of the most common malignancies in the female genital tract and poses serious health hazards. The gene P53 safeguards cell integrity however; a mutation in this gene increases the lifeline of the cells which are programmed for cell death. This particular gene participates in many human cancers including endometrial, ovarian and tubal carcinomas. In this study we screened exon 5 of p53 gene to find out whether this exon is a hotspot for mutations or not. We evaluated (n=45) samples of endometrial carcinoma and (n=45) controls from a local population. However, we...
Endometrial carcinoma is one of the most common malignancies in the female genital tract and poses serious health hazards. The gene P53 safeguards cel...
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160,58 |
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New strategies to develop antibiotics
ISBN: 9783659481703 / Angielski / Miękka / 72 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. The current available therapy against Pseudomonas aeruginosa and Leishmania spp infections for the well-known diseases such as cystic fibrosis and leishmaniasis (cutaneous, mucocutaneous and visceral) is far from satisfactory. It has been reported that established infections caused by P. aeruginosa are notoriously difficult to treat because this bacteria is usually resistant to many broad-spectrum antibiotics commonly used in hospitals and it may also acquire resistance to these drugs. Furthermore, a similar situation has been reported for leishmaniasis a complex of diseases caused by the...
The current available therapy against Pseudomonas aeruginosa and Leishmania spp infections for the well-known diseases such as cystic fibrosis and lei...
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160,58 |
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Lectins and Antioxidants in Fodder Plants
ISBN: 9783659516757 / Angielski / Miękka / 60 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Lectins are carbohydrate binding (glyco)proteins which are ubiquitous in nature. In plants they are distributed in various families and are widely distribution in all tissues. Some lectins are found to be toxic or anti-nutritional for man and animals. In general, nausea, bloating, vomiting and diarrhea characterize the oral acute toxicity of lectins. Antioxidants help to counter the detrimental effects of reactive oxygen species (ROS) and free radicals which cause degenerative diseases. They have been reported to be potential candidates to combat free radicals. Considering the probable...
Lectins are carbohydrate binding (glyco)proteins which are ubiquitous in nature. In plants they are distributed in various families and are widely dis...
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Expression Enhancement of Proinsulin Gene
ISBN: 9783659280924 / Angielski / Miękka / 60 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Human insulin is recombinant protein, which is responsible for the metabolism of carbohydrates and fat in the body. Insulin was first expressed in bacteria. The word insulin is coined from the Latin word "insula" meaning 'island' from the cells that produce insulin. The insulin hormone has the ability to control the blood sugar level by controlling the entry of glucose in the cells of skeletal muscles, liver and fat. Diabetes mellitus is a metabolic disorder, in which a person have high blood sugar due to the insufficiency in insulin production (type 1) or due to resistance to insulin (type...
Human insulin is recombinant protein, which is responsible for the metabolism of carbohydrates and fat in the body. Insulin was first expressed in bac...
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Homobrassinolide: A Potent Antihyperglycaemic Agent in Male Rats
ISBN: 9783659300042 / Angielski / Miękka / 52 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Hyperglycemia is a widely prevalent metabolic disorder clinically diagnosed as Diabetes. The clinical profile of diabetes recognized insulin-dependent and insulin-independent forms of this metabolic disorder, implicating pancreatic β-cells for their diminished capacity to produce insulin, and the glucose phosphorylating enzymes as well as cellular glucose transporters for diminished glucose utilization by the cells. In this context, the present work becomes significant. A result of this investigation speaks for itself and supports an extremely valuable mammalian role for a plant hormone...
Hyperglycemia is a widely prevalent metabolic disorder clinically diagnosed as Diabetes. The clinical profile of diabetes recognized insulin-dependent...
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Séparation Du Mélange Eau-Éthanol Par Le Procédé de Pervaporation
ISBN: 9786131591242 / Francuski / Miękka / 72 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Les procA(c)dA(c)s membranaires les plus dA(c)veloppA(c)s sont: la dialyse, l'A(c)lectrodialyse, la micro filtration, l'ultrafiltration, la nanofiltration et l'osmose inverse. Les procA(c)dA(c)s membranaires en dA(c)veloppement sont: la sA(c)paration par membrane liquide, par membranes A(c)changeuses d'ions, la permA(c)ation gazeuse et la pervaporation. Les membranes disponibles actuellement prA(c)sentent une grande variA(c)tA(c). NA(c)anmoins, la recherche se fait toujours vers des membranes performantes afin de dA(c)velopper ces procA(c)dA(c)s. Nous avons essayA(c) A travers ce prA(c)sent...
Les procA(c)dA(c)s membranaires les plus dA(c)veloppA(c)s sont: la dialyse, l'A(c)lectrodialyse, la micro filtration, l'ultrafiltration, la nanofiltra...
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Dissecting metabolism in brown and white fat
ISBN: 9783639640953 / Angielski / Miękka / 76 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Studies on the metabolism of adipose tissue mainly use immortalized cell lines for in vitro investigations. However, their physiological behavior may differ strongly from in vivo processes. Therefore we established an extraction and differentiation protocol for primary brown and white adipocytes (pBACs and psWACs). As previous studies in iBACs and 3T3-L1 cells indicated that N-acetyltransferase 8-like (NAT8L) might play an important role in adipose tissue metabolism, we investigated its role in these primary cells. We found that NAT8L leads to increased mRNA expression levels of UCP1....
Studies on the metabolism of adipose tissue mainly use immortalized cell lines for in vitro investigations. However, their physiological behavior may ...
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160,58 |
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Estrés oxidativo en amaranto deteriorado
ISBN: 9783659008122 / Hiszpański / Miękka / 76 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. El cultivo del amaranto (Amaranthus hypochondriacus) o alegria, es uno de los cultivos mas antiguos de Mesoamerica, los aztecas y mayas lo consumian junto con el maiz y el frijol. Se caracteriza por su gran valor nutrimental reflejado en su contenido de minerales, fibra y lipidos, pero sobre todo, por su alto contenido proteico, el cual posee un balance adecuado de aminoacidos esenciales, siendo similar a las proteinas de la leche. Por otra parte, el almacenamiento inadecuado de semillas provoca reacciones de deterioro, las cuales estan relacionadas con la generacion de estres oxidativo. El...
El cultivo del amaranto (Amaranthus hypochondriacus) o alegria, es uno de los cultivos mas antiguos de Mesoamerica, los aztecas y mayas lo consumian j...
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160,58 |
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Proteomic Diversity in Xanthomonas Oryzae Pv. Oryzae from West Africa
ISBN: 9783659449741 / Angielski / Miękka / 56 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Proteomic is now increasingly considered as useful technique to reveal genetic diversity among different bacteria isolates differentiating live pathogens from dead ones. This book, therefore, reveals proteomic diversity of thirty Xanthomonas oryzae pv. oryzae (Xoo) isolates, the causative agent of rice bacterial leaf blight disease in West Africa, using isozyme polyacrylamide gel electrophoresis (PAGE) analysis. The study revealed 23 isozyme loci in which SKDH produced 33.3-93.3 % polymorphism, EST and G6PH equally gave 40-96.7 % polymorphism within the Xoo isolates enzyme profile....
Proteomic is now increasingly considered as useful technique to reveal genetic diversity among different bacteria isolates differentiating live pathog...
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Le Biosenseur Au Service de la Pharmacologie
ISBN: 9783841736475 / Francuski / Miękka / 72 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Les senseurs sont des dispositifs analytiques rendant capable la dA(c)tection de molA(c)cules diverses. Les entreprises pharmaceutiques et les laboratoires d'analyses, pour ne citer que ces exemples, utilisent sans cesse des senseurs, que ce soit pour une simple dA(c)tection, ou plus, pour doser des molA(c)cules dans un produit bien spA(c)cifique, que ce soit dans le cadre de la recherche et dA(c)veloppement, d'un contrAle qualitA(c) ou d'une analyse quantitative. Parmi ces senseurs, on retrouve la catA(c)gorie des biosenseurs, senseurs qui ont A(c)tA(c) bio-fonctionnalisA(c)s. Dans ce livre,...
Les senseurs sont des dispositifs analytiques rendant capable la dA(c)tection de molA(c)cules diverses. Les entreprises pharmaceutiques et les laborat...
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160,58 |
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Potential Exploitation of Microbial Xylanase
ISBN: 9783659576997 / Angielski / Miękka / 88 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Xylan is a heteropolymer consisting of a backbone of b-1,4-linked D-xylopyranose residues with a-L-arabinofuranose, acetyl and glucuronic acid side chains. Xylanase (endo-1,4-b-D-xylanohydrolase; EC 3.2.1.8) , the xylan-degrading enzyme, has been reported from microorganisms. Xylanases have gained importance because of their extensive applications in industries especially in paper and pulp industry, bioconversion of agricultural wastes, fruit softening and clarifying juices, texture improvement of bakery products, production of xylose, textile industry, improvement of nutritional value of...
Xylan is a heteropolymer consisting of a backbone of b-1,4-linked D-xylopyranose residues with a-L-arabinofuranose, acetyl and glucuronic acid side ch...
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160,58 |
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Microcontact Printing Development of Thiolated Glycosaminoglycans
ISBN: 9783639725674 / Angielski / Miękka / 68 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. It is shown that cells interact with glycosaminoglycans (GAGs) to regulate their own growth, adhesion and motility. Fibroblast seeding on immobilized hyaluronic acid derivatives upon amino and vinyl terminated surfaces reveal such mechanisms. Additionally, in vitro cell dynamics depend on surface chemistry and topography which also influence biocompatibility. The purpose of this work is to develop a microcontact printing approach to immobilize patterns of thiolated hyaluronic acid (t-HA) and thiolated chondroitin sulphate (t-CS) upon vinyl terminated glass by means of a functionalized...
It is shown that cells interact with glycosaminoglycans (GAGs) to regulate their own growth, adhesion and motility. Fibroblast seeding on immobilized ...
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160,58 |
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Topographic and Functional Investigation of Erythrocyte-Ghosts
ISBN: 9783639491180 / Angielski / Miękka / 72 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. The hemoglobin free human red blood cells - so called ghosts - represent the same features as human red blood cells, but their membranes are stiffer. Through the stiffer surface, ghosts are most suitable for membrane analysis with atomic force microscope. Erythrocyte ghosts immobilized and fixated on glass slides enable a topographic investigation of the membrane and a functional analysis of their epitopes. Using the atomic force microscope and Acetal-PEG-NHS-linkers to attach monoclonal Rhesus-Anti-body clones to cantilever-tips, the Rhesus epitope can be analyzed. Refining this technique...
The hemoglobin free human red blood cells - so called ghosts - represent the same features as human red blood cells, but their membranes are stiffer. ...
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Methods to Study Alzheimer's disease
ISBN: 9783659617553 / Angielski / Miękka / 56 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Alzheimer's disease is one of the most common neurological disease which is characterized by the presence of -amyloid (A ) peptides and highly phosphorylated tau proteins in the brain. Study of AD became more reliable with the development of new advances both in the in-vivo (like PET, SPECT, MRI, MRP, FMR Imaging, NMR etc) and in-vitro (CD, FTIR, Dye Binding, TEM, STEM, STM, AFM, FRET etc.) methods. They are used in the study of pathogenesis and diagnosis of AD. Every method has its own advantages and limitations. In the present review, we have tried to explain the advancement of different...
Alzheimer's disease is one of the most common neurological disease which is characterized by the presence of -amyloid (A ) peptides and highly phospho...
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160,58 |
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Biological effects of external electrostatic field
ISBN: 9783659620003 / Angielski / Miękka / 72 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. The investigations on the influence of external electrostatic fields on biological objects and particularly on the human health have been initiated since 1960s. A multitude of studies have been performed on whether the electric fields generated by electrical installations represent any kind of health risk. Nevertheless, till now the data on exposure of electrostatic field are insufficient to draw conclusions regarding the possibility of health effects. Results obtained in some investigations are inconstant, this impede to draw the overall picture of alterations of biological processes and to...
The investigations on the influence of external electrostatic fields on biological objects and particularly on the human health have been initiated si...
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160,58 |
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Possibili terapie contro obesità psicosi e dipendenza da sostanze
ISBN: 9783639657425 / Włoski / Miękka / 56 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Questo lavoro ha come soggetto principale il recettore 5HT2c della serotonina e i nuovi composti agonisti e antagonisti di questo recettore, che possono essere utilizzati in campo terapeutico. Qui vengono descritti i meccanismi attraverso i quali la serotonina interagisce con il sistema dopaminergico, e grazie proprio ai suoi recettori 5HT2c riesce a modulare i livelli di dopamina, caratteristica molto importante per lo sviluppo di nuovi farmaci con azione contro l'obesita, i disturbi psicotici e l'abuso di sostanze.
Questo lavoro ha come soggetto principale il recettore 5HT2c della serotonina e i nuovi composti agonisti e antagonisti di questo recettore, che posso...
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160,58 |
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Podocyturia: a new marker for diabetic nephropathy
ISBN: 9783659614255 / Angielski / Miękka / 56 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Nephropathy is a major complication of diabetes and the leading cause of end-stage renal disease; it is clinically characterized by proteinuria and progressive renal insufficiency. Human podocytes have been demonstrated to be functionally and structurally injured in the natural history of diabetic nephropathy. Urinary podocyte count and measurement of urinary podocyte specific markers (nephrin, synaptopodin, podocin and podocalyxin) have been developed to detect podocyte injury. We discuss the emerging clinical importance of the urinary podocyte count in experimental and human glomerular...
Nephropathy is a major complication of diabetes and the leading cause of end-stage renal disease; it is clinically characterized by proteinuria and pr...
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160,58 |
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