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Chilina gibbosa: sentinel species for water contamination?
ISBN: 9783659642678 / Angielski / Miękka / 76 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Pesticides are used all around the world in agriculture, having a huge impact on non-target species. In Argentina, the most used pesticide is the organophosphate azinphos-methyl which is related to the inhibition of the acetylcholinesterase enzyme. Exposure to organophosphate insecticides is generally evaluated by the measuring of cholinesterase activity, but in recent years carboxylesterases have also been postulated as good biomarkers. Water contamination by pesicides used in agriculture is a world wide problem and as consequence of the considerable decrease in the diversity of mollusk...
Pesticides are used all around the world in agriculture, having a huge impact on non-target species. In Argentina, the most used pesticide is the orga...
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Differential Proteomic Methods and their Significances
ISBN: 9783659647048 / Angielski / Miękka / 52 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Differential proteomics analysis became more important and reliable with the development of new advances both in the labeled (like DIGE, ICAT, iTRAQ, ICPL) as well as label-free methods used in the field of differential proteomics. Validation of differential proteomics results have been done by ELISA, western blotting, immunohistochemistry, RT-PCR and real time qPCR. Differential proteomics are successfully used in the diverse studies like biomarker discovery, agriculture, pathogenesis, drug resistance and organism adaptation at diverse environmental stress. Every proteomic methods have its...
Differential proteomics analysis became more important and reliable with the development of new advances both in the labeled (like DIGE, ICAT, iTRAQ, ...
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Inducing genetic change in cancer cells using lasers
ISBN: 9783659646485 / Angielski / Miękka / 56 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. In this book, we demonstrate a new single cell optoporation and transfection technique using femtosecond Gaussian laser beam and optical tweezers. Tightly focused near-infrared (NIR) femtosecond laser pulse was employed to transiently perforate the cellular membrane at a single point of MCF-7 cancer cell. A distinct technique is developed by trapping the microparticle using optical tweezers to focus femtosecond laser exactly on the cell membrane to puncture it for the desired time. Subsequently, calculated amount of external gene was introduced in the cell by trapping and inserting same...
In this book, we demonstrate a new single cell optoporation and transfection technique using femtosecond Gaussian laser beam and optical tweezers. Tig...
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Baza Danych Ligandów Bialek
ISBN: 9783639891836 / Polski / Miękka / 56 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Niniejsza praca stanowi opis zrealizowanych przez autora projektow dotycz cych zagadnienia wspomaganego komputerowo projektowania lekow. Projekty b d ce tematem pracy to baza danych ligandow bia ek LIGANSdb oraz program do analizy rozk adu oddzia ywa w bia ku o nazwie PDP 1.0 (Potencial Density In Protein). LIGANDSdb to serwis internetwy dost pny pod adresem http: //crick.cm-uj.krakow.pl/ligandsdb. LIGANDSdb posiada dwa rodzaje przeszu-kiwania zasobow: przeszukiwanie po nazwach bia ek dostarczaj ce listy ligandow, ktore wi si z dan protein oraz przeszukiwanie po nazwach ligandow ktorego...
Niniejsza praca stanowi opis zrealizowanych przez autora projektow dotycz cych zagadnienia wspomaganego komputerowo projektowania lekow. Projekty b d ...
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Caracterización inmunológica de Proteínas de Pared en cepas de Candida
ISBN: 9783659061615 / Hiszpański / Miękka / 72 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. La mayoria de las micosis oportunistas son ocasionadas por Candida albicans y otras especies denominadas Candida no Candida albicans, las cuales presentan diferencias en sensibilidad a antifungicos y problemas para su diagnostico, el cual puede presentar ambiguedades dependiendo del metodo de eleccion, ademas de requerir varias etapas y con ello tiempo para la determinacion del agente causal. Este comportamiento ha hecho necesaria la busqueda de nuevos metodos diagnosticos para las diferentes especies de Candida. En este trabajo se propone la diferenciacion inmunologica de las diferentes...
La mayoria de las micosis oportunistas son ocasionadas por Candida albicans y otras especies denominadas Candida no Candida albicans, las cuales prese...
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Impact of Hydrocarbon Industrial Wastes on Soil Microbial Activities
ISBN: 9783659647086 / Angielski / Miękka / 52 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Industrial wastes are having high impact on environment. Hydrocarbon industry is one of the biggest industries emitting huge amounts of wastes into environment. These wastes have high impact on the soil physico-chemical, biological and enzyme properties. This book gives detailed information regarding the effect of these wastes on soil health. First chapter give brief introduction about the background of this field. Second chapter deals with various procedures followed. Third chapter specifies results and discussion. Fourth chapter provides conclusion and followed by fifth chapter with...
Industrial wastes are having high impact on environment. Hydrocarbon industry is one of the biggest industries emitting huge amounts of wastes into en...
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160,58 |
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Estudo de modelo de inibição de calicreínas teciduais humanas 5 e 7
ISBN: 9783639741407 / Portugalski / Miękka / 76 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. A descoberta de um novo farmaco e um processo laborioso que demanda tempo e dinheiro. Nos ultimos anos, a industria farmaceutica e a academia vem utilizando de ferramentas de bioinformatica junto a ensaios biofisicos pra diminuir o tempo e custos com essas descobertas. Neste livro veremos um exemplo de como esse trabalho pode ser desenvolvido. As calicreinas teciduais humanas 5 e 7 sao enzimas envolvidas no processo de descamacao da pele. Quando os processos de regulacao falham, doencas como a psoriase surgem. A descoberta de inibidores de modo aleatorio seria laborioso. Assim, partindo da...
A descoberta de um novo farmaco e um processo laborioso que demanda tempo e dinheiro. Nos ultimos anos, a industria farmaceutica e a academia vem util...
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ADR s of ACE inhibitors
ISBN: 9783659674037 / Angielski / Miękka / 52 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. An ACE inhibitor (or angiotensin-converting-enzyme inhibitor) is a pharmaceutical drug used primarily for the treatment of hypertension (elevated blood pressure) and congestive heart failure. This group of drugs causes dilation of blood vessels, which results in lower blood pressure. In treating heart disease ACE inhibitors are usually used with other medications. A typical treatment plan will often include an ACE inhibitor, beta blocker, a long-acting nitrate and a calcium channel blockerin combinations that are adjusted to the individual patient's needs.
An ACE inhibitor (or angiotensin-converting-enzyme inhibitor) is a pharmaceutical drug used primarily for the treatment of hypertension (elevated bloo...
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Metabolic Fate of Arachidonic Acid
ISBN: 9783659212291 / Angielski / Miękka / 52 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. This Book depicts the metabolic fate of Arachidonic acid in general through three major pathways viz. Lipoxygenase, Cyclooxygenase & Cytochrome P450 monoxygenase pathways. However, special emphasis has been given to the Lipoxygenase pathway. The book takes into account of the recent findings in the above pathways for instance discovery of the Lipoxygenase system in bacteria. Also, new genes of the Lipoxygenase pathway and its orthologous genes in mice are also well compared. In Summary, the book is a concise yet comprehensive literature on Arachidonic acid metabolism with special interest on...
This Book depicts the metabolic fate of Arachidonic acid in general through three major pathways viz. Lipoxygenase, Cyclooxygenase & Cytochrome P450 m...
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Biofunctionalization of chitosan
ISBN: 9783659682179 / Angielski / Miękka / 68 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Chitosan (aminopolysaccharide) is a natural polymer. Thanks to excellent functional properties, it was found to be a good natural source in various applications such as biomedical, agricultural, functional food, wastewater purification and environmental protection. However, practical use of chitosan was generally limited due to its weak solubility in neutral pH, its poor workability and low antioxidant activity. For a breakthrough in utilization, the functionalization of chitosan will be a suitable solution. Enzymatic or chemical functionalizations of chitosan were carried out based on its...
Chitosan (aminopolysaccharide) is a natural polymer. Thanks to excellent functional properties, it was found to be a good natural source in various ap...
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Teratogénesis producida por la Diabetes e Hipertermia
ISBN: 9783659090912 / Hiszpański / Miękka / 64 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Las mujeres diabeticas embarazadas presentan incremento en la mortalidad perinatal y desarrollo de malformaciones congenitas en el feto, con una frecuencia de 2 a 4 veces mas elevada que en hijos de mujeres no diabeticas. Se ha observado que existen factores fisicos, quimicos y biologicos que pueden modificar las condiciones fisiologicas durante el embarazo, alterando los efectos teratogenicos desencadenados por la condicion diabetica, induciendo en la mayoria de los casos, exacerbacion de los mismos. Es de importancia conocer y evaluar experimentalmente los posibles efectos que puedan...
Las mujeres diabeticas embarazadas presentan incremento en la mortalidad perinatal y desarrollo de malformaciones congenitas en el feto, con una frecu...
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Antitumor activity of extracts from antartic macroalgae
ISBN: 9783659696169 / Angielski / Miękka / 52 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. (Chapter 1) This research aimed evaluates the antitumor activity against the malignant tumor Glioblastoma Multiforme based in extracts from Antarctic seaweeds Iridaea cordata and Desmarestia anceps collected at Peninsula Antarctica. (Chapter 2) Glioblastoma, a grade IV glioma, is a type of primary malignant brain tumor which shows a higher incidence in adults. Because of its poor prognosis, there is an incentive for new drug discovery. Accordingly, knowing the anticancer potential of some compounds isolated from seaweeds, our goal is evaluate the antiglioma activity from endemic Rhodophyta...
(Chapter 1) This research aimed evaluates the antitumor activity against the malignant tumor Glioblastoma Multiforme based in extracts from Antarctic ...
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Spirulina Probable Insulin Source
ISBN: 9783659744648 / Angielski / Miękka / 52 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Insulin, a hormone secreted by the beta cells of pancreas allows the body to use the sugar content in food that we eat for energy as well as store glucose for future use thereby maintaining the blood sugar level. In Diabetes mellitus, pancreas no longer produces adequate insulin or cells become resistant to the insulin that is produced, leading to hyperglycemia condition in humans. Spirulina, is a naturally occurring fresh water Cyanobacteriuum and is enriched with proteins and essential nutrients. In this report, we studied for a herbal source of Insulin from Spirulina, as it contains the...
Insulin, a hormone secreted by the beta cells of pancreas allows the body to use the sugar content in food that we eat for energy as well as store glu...
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Enzyme and the Steady State Enzymology
ISBN: 9783659748912 / Angielski / Miękka / 52 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Enzymes are generally globular proteins that catalyze chemical reactions, the rates of which can be decreased by inhibitors, pH and temperature. Enzymes have been produced commercially with unique identifier developed by The International Union of Biochemistry and Molecular Biology. The enzyme application could be found in many industrial processes and pharmaceutical purposes. The Michaelis-Menten rate equation is discussed in the various steady state enzymology.
Enzymes are generally globular proteins that catalyze chemical reactions, the rates of which can be decreased by inhibitors, pH and temperature. Enzym...
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Alternative Energy Source by Characterization and Transesterification
ISBN: 9783659781841 / Angielski / Miękka / 52 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. This book briefly examines the increasing degradation of the environment and emission of greenhouse gases into the atmosphere which has has led to the research and development of alternative to fossil fuels. Vegetable oil has been cited as one of these renewable sources; it is a triglyceride and composed of fatty acids is used in the production of Bio-diesel, an alternative source of energy. Consequently, bio-diesel has become more attractive recently because of its environmental benefits and the fact that it is made from renewable resources. Vegetable oil, as alternative engine fuel, is...
This book briefly examines the increasing degradation of the environment and emission of greenhouse gases into the atmosphere which has has led to the...
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SOD y COMMD1 dos proteínas de interés biomédico
ISBN: 9783659098277 / Hiszpański / Miękka / 64 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Esta compilacion contiene los articulos cientificos "Superoxido Dismutasa: Un candidato terapeutico para el estres oxidativo" y "COMMD1: Una proteina reguladora multifuncional," donde se discute la estructura, el mecanismo molecular y la funcion biologica de la enzima Superoxido Dismutasa y de la proteina reguladora COMMD1. Estas dos proteinas se relacionan con multiples eventos celulares tanto fisiologicos como patologicos y aunque han sido ampliamente estudiadas, su potencial biomedico apenas esta emergiendo. Ambas constituyen blancos terapeuticos atractivos y promisorios para el...
Esta compilacion contiene los articulos cientificos "Superoxido Dismutasa: Un candidato terapeutico para el estres oxidativo" y "COMMD1: Una proteina ...
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Canais Aniônicos de Membranas Celulares
ISBN: 9783841707048 / Portugalski / Miękka / 72 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. O aumento do volume celular induz ao aumento na condutancia anionica em todos os tipos celulares de vertebrados que tem sido examinados. Neste estudo, utilizando tecnicas de medida de corrente ionica atraves da membrana celular, buscamos identificar canais anionicos envolvidos na regulacao do volume de celulas GH3 submetidas ao estresse hipotonico, e seu possivel papel como via condutiva do ATP, que e liberado para o espaco extracelular nesta condicao. Para a medida das correntes de cloreto ativadas por aumento de volume, utilizamos a tecnica de "patch clamp" na modalidade "whole-cell,"...
O aumento do volume celular induz ao aumento na condutancia anionica em todos os tipos celulares de vertebrados que tem sido examinados. Neste estudo,...
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Troid Disfonksiyonlu Farelerde Egzersizin Oksidan/Antioksidan Etkisi
ISBN: 9783639811131 / Turecki / Miękka / 52 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Fiziksel egzersiz esnas nda artan oksijen tuketimi ile serbest oksijen radikallerinin olu umu aras nda bir ili kinin oldu u, yo unlu una ve suresine ba l olarak egzersizin oksidatif stres olu turabilece i de i ik ara t rmalarda rapor edilmi tir. Bu cal mada deneysel olarak hipertiroidi olu turulan Sprague-Dawley cinsi erkek ratlar n karaci er dokusunda Total Antioksidan Status (TAS) ve Total Oksidan Status (TOS) parametreleri uzerine duzenli yap lan dayan kl l k egzersizinin etkilerinin olup olmad ara t r lm t r."
Fiziksel egzersiz esnas nda artan oksijen tuketimi ile serbest oksijen radikallerinin olu umu aras nda bir ili kinin oldu u, yo unlu una ve suresine b...
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The need to choose the fatty acids in our daily meals
ISBN: 9783659808340 / Angielski / Miękka / 56 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Our diet contains a complex mixture of fats and oils whose basic structural components are fatty acids. We generally consume at least 20 different types of fatty acids which are classified as saturated (SFA), monounsaturated (MUFA) and polyunsaturated fatty acids (PUFA). The types of fatty acids in our diet determine the types of fatty acids that are available to the composition of cell membranes which carry out many functions that are necessary for physiological health. Increased dietary intake of omega-6 leads to production of prostaglandins, thromboxanes and leukotrienes and interferes...
Our diet contains a complex mixture of fats and oils whose basic structural components are fatty acids. We generally consume at least 20 different typ...
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Enzimas con actividad ribonucleasa en plantas laticíferas
ISBN: 9783659031328 / Hiszpański / Miękka / 72 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. |
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