Preparation and Evaluation of Magnetic Microspheres of Mesalamine
ISBN: 9783848483525 / Angielski / Miękka / 160 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. When a patient has no alternative towards treatment of disease then Magnetic microspheres come into view.Magnetic Microspheres have basically two advantages that is Reticuloendothelial clearance can be minimised and target site specificity can be increased.For Drug targeting, various carrier systems have been exploited like liposomes, nanospheres, microspheres, macromolecules etc. The difficulty of targeting drugs in vivo using these carrier systems is that the body contains 3 major tubes: the vascular, extracellular & intracellular compartments. Despite having several advantages, one most...
When a patient has no alternative towards treatment of disease then Magnetic microspheres come into view.Magnetic Microspheres have basically two adva...
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cena:
375,31 zł |
Brittle Fracture Index as a Tool for Tablet Binder Selection
ISBN: 9783659271601 / Angielski / Miękka / 164 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. The effect of binder type and concentration on six high dose drugs was evaluated. The drugs which are used in this experiment are already in market and are available at a very high dose of 500mg and above. Three binders were used in the work at two different user levels. The binders are chosen of different chemistries so in order to predict a optimized formulation for each of the drug. The brittle fracture index of the formulation is calculated by compressing tablets with hole, the hole is an inbuilt defect which will help in propagation of crack into the tablet and enable capping and...
The effect of binder type and concentration on six high dose drugs was evaluated. The drugs which are used in this experiment are already in market an...
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cena:
375,31 zł |
In- Vitro and In- Vivo Interaction studies of Leflunomide
ISBN: 9783659372261 / Angielski / Miękka / 168 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Rheumatoid arthritis (RA) is a chronic inflammatory joint disorder in which people suffer from joint as well as neurobiological disorder. These patients take multiple drugs which opens the chances of drug interaction. Therefore this book deals with the in-vitro and in-vivo interaction studies of leflunomide (a leading DMARD to treat RA) with NSAIDs, essential & trace elements. For in-vitro studies, methods were developed & validated (via ICH guide lines)on UV-spectrophotometer and HPLC which were then applied for drug interaction study. Leflunomide-metals complexes were also synthesized and...
Rheumatoid arthritis (RA) is a chronic inflammatory joint disorder in which people suffer from joint as well as neurobiological disorder. These patien...
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375,31 zł |
Animal Alternative Methods in Drug Approval Process
ISBN: 9783659474798 / Angielski / Miękka / 184 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Animals have been in use in the drug research and development process in lieu of providing safety and efficacy data in the past several decades, especially after the thalidomide and sulphanilamide tragedies. But due to various reasons like continuous pressure from animal welfare groups all over the world and continuous advancements in the field of non-animal alternative testing strategies, demand for substitution of animals to ascertain drug safety is catching momentum. The 3R'principle i.e. reduction, refinement and replacement approach has become the motto of humane treatment towards...
Animals have been in use in the drug research and development process in lieu of providing safety and efficacy data in the past several decades, espec...
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375,31 zł |
Laboratory Manual of Dispensing Pharmacy
ISBN: 9783659500824 / Angielski / Miękka / 168 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Dispensing Pharmacy involves preparation of dosage forms and traditionally considered as an art. Here an effort is made in which all the necessary information is compiled and kept at one place systematically and in simple language. The experiments are divided for convenience into two parts, namely preparations and prescriptions. Preparations part includes discussion on aromatic waters, syrups, elixirs, linctuses, solutions, suspensions, liniments. Prescriptions part consists of powders, emulsions, effervescent salts. Appendices included at the end of the book help the students for quick...
Dispensing Pharmacy involves preparation of dosage forms and traditionally considered as an art. Here an effort is made in which all the necessary inf...
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cena:
375,31 zł |
Formulation, Characterization of Stealth Liposomes Targeting Cancer
ISBN: 9783659484346 / Angielski / Miękka / 196 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Cancer is a Major cause of death in todays fast changing world. Many recent developments involve in targeting Cancer cells without harming the normal celss. This book deals with Targeting Gemcitabine Containing Stealth (PEG Coated) Liposomes targeting Cancer cells. Breast Cancer cells are researched in this book. Cytotoxic and biodistribution studies are successfully carried out. Detailed methods of various preparations of liposomes are mentioned. Various characterization techniques like SEM and TEM are carried out and explained. Cytotoxic studies like cell line study is carried out...
Cancer is a Major cause of death in todays fast changing world. Many recent developments involve in targeting Cancer cells without harming the normal ...
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375,31 zł |
Metronidazole Controlled Release Delivery Systems
ISBN: 9783659532306 / Angielski / Miękka / 420 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. I am deeply thankful to GOD by the grace of whom the present work was realized. To my family, whose vision, enthusiasm, and unswerving support helped to make a lifelong dream come true. Several approaches are currently utilized in the prolongation of the gastric residence time, including floating drug delivery systems (FDDS), also known as hydrodynamically balanced systems (HBS). Therefore, the aim of this work was to formulate the metronidazole as it has an important role in the treatment of Helicobacter pylori infection of the stomach in different controlled release forms to prolong...
I am deeply thankful to GOD by the grace of whom the present work was realized. To my family, whose vision, enthusiasm, and unswerving support helped...
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cena:
375,31 zł |
Sozdanie Liposomal'nykh Lekarstvennykh Form Protivoopukholevykh Preparatov
ISBN: 9783659283888 / Rosyjski / Miękka / 180 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Diagnoz rak stal prigovorom dlya mnogikh lyudey.V mire ezhegodno fiksiruetsya 12 millionov novykh sluchaev onkologicheskikh zabolevaniy. V 40-kh gg. KhKh v. otechestvennyy uchenyy L.F.Larionov predlozhil ispol'zovat' aminokisloty, obespechivayushchie selektivnost' deystviya preparatov na DNK rakovykh kletok, v kachestve nositeley tsitotoksicheskoy khimicheskoy gruppy bis-( -khloretil)-amina. V sootvetstvii s etoy ideey v FGBU RONTs im. N.N. Blokhina RAMN sintezirovany pervye otechestvennye preparaty: sarkolizin i ego peptidnoe proizvodnoe - tsifelin. No terapevticheskiy effekt sarkolizina...
Diagnoz rak stal prigovorom dlya mnogikh lyudey.V mire ezhegodno fiksiruetsya 12 millionov novykh sluchaev onkologicheskikh zabolevaniy. V 40-kh gg. K...
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375,31 zł |
Laboratory Manual of Pharmaceutical Technology
ISBN: 9783659536885 / Angielski / Miękka / 188 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. The practicals of this subject include the manufacture of dosage forms like tablets, capsules, injections, infusions, liquid orals, semisolids, and cosmetics. The students are asked to prepare dosage formulations in a laboratory scale. However they prepare formulations by keeping the industrial practice in view. Therefore in most of the cases the students need to use the instruments that are used in industry or otherwise mimic the conditions similar to that of industry. For every formulation and for every group of formulations general principles are written. As these practicals are for final...
The practicals of this subject include the manufacture of dosage forms like tablets, capsules, injections, infusions, liquid orals, semisolids, and co...
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cena:
375,31 zł |
Preclinical evaluation of antidiabetic properties of Ficus deltoidea
ISBN: 9783659545115 / Angielski / Miękka / 176 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Diabetes mellitus describes as heterogeneous disease caused by a combination of inherited and acquired deficiency in secretion of insulin and by reduced sensitivity of the tissues to secreted insulin. The number of people with diabetes is increasing owing to population growth, ageing, and sedentary lifestyle. Current medicine despite the efficacy showed wide range of side effects, which itself increases the annual rate of morbidity and mortality of diabetes mellitus. In this circumstance there is urge for novel medicine with lower adverse effect. Standardized natural product that derived from...
Diabetes mellitus describes as heterogeneous disease caused by a combination of inherited and acquired deficiency in secretion of insulin and by reduc...
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375,31 zł |
Induced Nephrotoxicity - A New Approach
ISBN: 9783659553738 / Angielski / Miękka / 160 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Portulaca oleracea extract may be used to cure or prevent cisplatin-induced renal toxicity without any adverse effect; hence it can serve as a novel combination agent with cisplatin to limit renal injury. 24 wistar rats were randomly divided into 6 groups with varied treatment plan of Methanolic Extract of Portulaca Oleracea (MEPO) and Cisplatin for 7 day duration. The treatment effects on average body weight, relative kidney weight, water consumption, serum creatinine level, serum uric acid and histology of the rat kidney were accessed. Results showed significantly decreased serum...
Portulaca oleracea extract may be used to cure or prevent cisplatin-induced renal toxicity without any adverse effect; hence it can serve as a novel c...
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375,31 zł |
Use of Herbs in Urolithiasis; Results from Experimental Studies
ISBN: 9783659574689 / Angielski / Miękka / 160 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Urolithiasis, the formation of urinary stones, is one of the oldest known diseases. Its incidence and prevalence is constantly increasing, sparing no geographical, cultural or racial boundaries. Currently available stone removal techniques are costly and have some serious side effects with limitation of recurrence of stone formation. The agents used clinically for prophylactic therapy are primarily aimed to correct the underlying metabolic disorders but the evidence for their effectiveness is still not convincing. Therefore, there is a need to look for an alternative therapy. This study...
Urolithiasis, the formation of urinary stones, is one of the oldest known diseases. Its incidence and prevalence is constantly increasing, sparing no ...
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375,31 zł |
Nanoparticulate drug delivery of an anticancer drug
ISBN: 9783659599385 / Angielski / Miękka / 168 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. This book is about formulation and evaluation of methoxy polyethylene glycol epsilone polycaprolactone (MPEG-EPCL) nanoparticles containing Gemcitabine hydrochloride. Gemcitabine is a nucleoside analogue, used in treatment of various carcinomas such as non small cell lung cancer, pancreatic cancer, ovarian cancer and breast cancer. The major setbacks to the conventional therapy with Gemcitabine include its short half-life and highly hydrophilic nature. Gemcitabine loaded (poly-e-caprolactone)-methoxy poly(ethylene glycol) copolymers that were used for the preparation of nanoparticles with the...
This book is about formulation and evaluation of methoxy polyethylene glycol epsilone polycaprolactone (MPEG-EPCL) nanoparticles containing Gemcitabin...
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cena:
375,31 zł |
Transdermal Patch Loaded Nanoparticles Containing Antidiabetic Drugs
ISBN: 9783659575556 / Angielski / Miękka / 196 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Biodegradable nanoparticles of insulin and Repaglinide were prepared by using biodegradable polymers and lipids. The prepared nanoparticles were evaluated by physicochemical parameters and in-vitro drug release. The optimized nanoparticle formulation of insulin and Repaglinide were loaded into Transdermal patch. These patches were subjected to release studies and preclinical evaluation parameters like bioavailability studies. Based on above studies, it was concluded that a single patch is suitable to control diabetes for more than 7 days
Biodegradable nanoparticles of insulin and Repaglinide were prepared by using biodegradable polymers and lipids. The prepared nanoparticles were evalu...
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375,31 zł |
Validation of Dietary Supplements
ISBN: 9783659638237 / Angielski / Miękka / 168 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. An RP-HPLC method was developed and validated for simultaneous estimation of active marker components of Boswellia serrata extract containing Boswellic acids (KBA and AKBA), Withania somnifera extract containing Withaferin A and Cissus quadrangularis extract containing Stigmasterol in their combined dosage form as Tablet or capsule or powder blend. RP-HPLC method was developed and validated; and successfully applicable for estimation of desired components from the formulation. Prospective process validation was conducted for tablet manufacturing process of LCOX tablet containing the above...
An RP-HPLC method was developed and validated for simultaneous estimation of active marker components of Boswellia serrata extract containing Boswelli...
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375,31 zł |
A pharmaceutical study on an antihypertensive drug
ISBN: 9783659674389 / Angielski / Miękka / 192 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. This book discusses novel techniques of solubility & dissolution enhancement of -poorly water soluble drug- Olmesartan medoxomil. Olmesartan medoxomil is a selective Angiotensin II receptor blocker drug used in the treatment of hypertension. It is a model drug of the Biopharmaceutical Classification System (BCS) class II which is characterized by poor water solubility and good permeability.It suffers from low bioavailability following oral administration using traditional dosage forms due to its poor aqueous solubility and efflux by drug resistance pumps in the gastrointestinal tract. It...
This book discusses novel techniques of solubility & dissolution enhancement of -poorly water soluble drug- Olmesartan medoxomil. Olmesartan medoxomil...
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375,31 zł |
Application of Clay Polymer Nanocomposite as Drug Delivery Vehicle
ISBN: 9783659745805 / Angielski / Miękka / 192 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. In medical and pharmaceutical field, the necessity of tailor made drug delivery system has attained significant attention. This suggests that we should take a lead in the area of drug delivery systems. Clay is viable to drug delivery systems, and is expected to provide sustained release characteristics as well as enhanced mechanical properties owing to their layered structure. One of the clay that is montmorillonite act as an adsorbs dietary toxins, bacterial toxins associated with gastrointestinal disturbance, hydrogen ions in acidosis, and metabolic toxins such as steroidal metabolites...
In medical and pharmaceutical field, the necessity of tailor made drug delivery system has attained significant attention. This suggests that we shoul...
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cena:
375,31 zł |
Estimation Of Atorvastatin, Fenofibrate And Fenofibric Acid In H.Plasma
ISBN: 9783659749988 / Angielski / Miękka / 164 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. A novel, precise, accurate and rapid isocratic reversed phase high performance liquid chromatographic method was developed and validated for the simultaneous estimation of Atorvastatin, Fenofibrate and its active metabolite, Fenofibric acid in human plasma. The method showed good separation and resolution for Atorvastatin, Fenofibrate and Fenofibric acid with hypersil ODS C18 column (4.6 x 250mm, 5um) using acetonitrile and water adjusted to pH 2.5 with ortho-phosphoric acid (85: 15) as mobile phase at a flowrate of 1 mL/min and wavelength of 288nm. The calibration curves were linear over the...
A novel, precise, accurate and rapid isocratic reversed phase high performance liquid chromatographic method was developed and validated for the simul...
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375,31 zł |
Preparation and Evaluation of Meloxicam Microsponges
ISBN: 9783659698163 / Angielski / Miękka / 176 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Meloxicam (MLX) is a highly potent, non - steroidal anti - inflammatory drug (NSAID), is used for the treatment of rheumatoid arthritis, osteoarthritis and other joint diseases. However, the gastrointestinal tract (GI T) adverse effects, such as stomachache, indigestion, and patient compliance are weaknesses the oral and injectable MLX administrations. MLX poor water solubility can give rise to many formulation problems that reduce s its therapeutic efficiency and bioavailability. The objective of this study was to develop a transdermal gel formulation of MLX microsponges in order to enhance...
Meloxicam (MLX) is a highly potent, non - steroidal anti - inflammatory drug (NSAID), is used for the treatment of rheumatoid arthritis, osteoarthriti...
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375,31 zł |
Pulsatile Dosage
ISBN: 9783659774300 / Angielski / Miękka / 180 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Over the past two decades there has been a growing appreciation on the importance of circadian rhythms on GIT physiology and on disease states, together with the realization of the significance of the drug administration on resultant pharmacodynamic and pharmacokinetics parameters. The significance of these day-night variations has not been over looked from the drug delivery perspective and pharmaceutical scientists have displayed considerable ingenuity in development of time delayed drug delivery systems to address emerging Chronotherapeutic formulations. Pulsincap technique helps us to...
Over the past two decades there has been a growing appreciation on the importance of circadian rhythms on GIT physiology and on disease states, togeth...
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cena:
375,31 zł |