Portulaca oleracea extract may be used to cure or prevent cisplatin-induced renal toxicity without any adverse effect; hence it can serve as a novel combination agent with cisplatin to limit renal injury. 24 wistar rats were randomly divided into 6 groups with varied treatment plan of Methanolic Extract of Portulaca Oleracea (MEPO) and Cisplatin for 7 day duration. The treatment effects on average body weight, relative kidney weight, water consumption, serum creatinine level, serum uric acid and histology of the rat kidney were accessed. Results showed significantly decreased serum...
Portulaca oleracea extract may be used to cure or prevent cisplatin-induced renal toxicity without any adverse effect; hence it can serve as a novel c...