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Protein Misfolding and Disease
ISBN: 9781617373329 / Angielski / Miękka / 318 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. For decades it has been known that structured conformations are important for the proper functioning of most cellular proteins. However, appreciation that protein folding to the functional conformations as well as the structural maintenance of protein molecules are very complex processes has only emerged during the last ten years. The intimate interplay uncovered by this scientific development led us to realize that perturbations of the protein folding process and disturbances of conformational maintenance are major disease mechanisms. This development has given rise to the concept of...
For decades it has been known that structured conformations are important for the proper functioning of most cellular proteins. However, appreciation ...
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605,23 |
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Genetics and Genomics of Neurobehavioral Disorders
ISBN: 9781617373220 / Angielski / Miękka / 428 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. A clear and comprehensive account of how genetic abnormalities, neurobiology, and neuropsychology work together to manifest cognitive-behavioral dysfunction. The authors review the current status of research in autosomal disorders that produce cognitive-behavioral dysfunction and syndromal and nonsyndromal disorders that produce mental retardation. Comprehensive and up-to-date, Genetics and Genomics of Neurobehavioral Disorders integrates the molecular, genomic, neuropsychological, and neurobehavioral factors that produce learning disabilities and mental retardation into a coherent framework...
A clear and comprehensive account of how genetic abnormalities, neurobiology, and neuropsychology work together to manifest cognitive-behavioral dysfu...
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605,23 |
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Neurogenetics: Methods and Protocols
ISBN: 9781617372902 / Angielski / Miękka / 390 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. The rapid identification and characterization of genes of neurological relevance holds great potential for offering insight into the diagnosis, management, and und- standing of the pathophysiologic mechanisms of neurological diseases. This volume in the Methods in Molecular Biology series was conceived to highlight many of the contemporary methodological approaches utilized for the characterization of neu- logically relevant gene mutations and their protein products. Although an emphasis has been placed upon descriptions of methodologies with a defined clinical utility, it is hoped that...
The rapid identification and characterization of genes of neurological relevance holds great potential for offering insight into the diagnosis, manage...
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403,47 |
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Capillary Electrophoresis of Nucleic Acids
ISBN: 9781617371868 / Angielski / Miękka / 484 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. The development of PCR, which enables extremely small amounts of DNA to be amplified, led to the rapid development of a multiplicity of a- lytical procedures that permit use of this new resource for the analysis of genetic variation and for the detection of disease-causing mutations. The advent of capillary electrophoresis (CE), with its power to separate and a- lyze very small amounts of DNA, has also stimulated researchers to develop analytical procedures for the CE format. The advantages of CE in terms of speed and reproducibility of analyses are manifold. Furthermore, the high s- sitivity...
The development of PCR, which enables extremely small amounts of DNA to be amplified, led to the rapid development of a multiplicity of a- lytical pro...
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605,23 |
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Celiac Disease: Methods and Protocols
ISBN: 9781617371158 / Angielski / Miękka / 288 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Research into gluten sensitivity has never been more popular nor more exciting. Thus a call for a new book, Celiac Disease: Methods and Protocols, devoted entirely to techniques and technology seemed a most appropriate undertaking. I am therefore grateful to Professor J. M. Walker for inviting me to complete this task for Humana Press. To do this would have been imp- sible without the contributions of friends and colleagues from around the world who have devoted so much interest to the project. It has also been necessary for them to master the unique chapter-writing skills required of every...
Research into gluten sensitivity has never been more popular nor more exciting. Thus a call for a new book, Celiac Disease: Methods and Protocols, dev...
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605,23 |
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Retrotransposition, Diversity and the Brain
ISBN: 9783642094378 / Angielski / Miękka / 123 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. The human brain is remarkably complex, permitting sophisticated behavioural rep- toires, such as languages, tool use, self-awareness, symbolic thought, cultural learning and consciousness. Each human being is different, due in part to the uniqueness of the neuronal heterogeneity and interconnections in our brains. Brain complexity and neuronal diversity are strongly related. The diversity of single neurons provides the underpinnings for how neuronal circuits operate. How and when neuronal diversity is generated, both in embryonic and adult neurogenesis, remain unknown. In the immune system,...
The human brain is remarkably complex, permitting sophisticated behavioural rep- toires, such as languages, tool use, self-awareness, symbolic thought...
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403,47 |
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Hormonal and Genetic Basis of Sexual Differentiation Disorders and Hot Topics in Endocrinology: Proceedings of the 2nd World Conference
ISBN: 9781441980014 / Angielski / Twarda / 180 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Proceedings of the 2nd World Conference - Hormonal and Genetic Basis of Sexual Differentiation Disorders and Hot Topics in Endocrinology. The meeting took place at The Eden Roc Hotel in Miami Beach, Florida, 1/15/10 - 1/17-10. Endocrinology and more specifically, the area of sexual differentiation disorders is an evolving field of medicine. The diagnosis and treatment of Disorders of Sex Development (DSD) is multi-faceted. Proceedings of the 2nd World Conference - Hormonal and Genetic Basis of Sexual Differentiation Disorders and Hot Topics in Endocrinology. The meeti... |
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605,23 |
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Alterations of the Sister Chromatid Exchange frequency in peripheral lymphocytes caused by an Ironman triathlon
ISBN: 9783638910415 / Angielski / Miękka / 92 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Diploma Thesis from the year 2007 in the subject Medicine - Human Genetics, grade: 1,0, University of Vienna (Institut fur Ernahrungswissenschaften), 96 entries in the bibliography, language: English, abstract: The aim of the present study was to investigate the effect of a triathlon (3.8 km swim, 180 km cycle, 42,2 km run) on the genomic stability of nine highly trained non- professional athletes. Therefore, the SCE assay, a relevant biological response marker for genotoxicity in human biomonitoring studies PENDZICH et al., 1997] was performed using peripheral lymphocytes, on account of...
Diploma Thesis from the year 2007 in the subject Medicine - Human Genetics, grade: 1,0, University of Vienna (Institut fur Ernahrungswissenschaften), ...
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270,14 |
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Antiviral RNAi: Concepts, Methods, and Applications
ISBN: 9781617790362 / Angielski / Twarda / 428 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Viruses and RNAi share an intricate relationship at many levels. RNAi is an important antiviral defense mechanism in plants and invertebrates, microRNAs - of viral or cellular origin - affect many aspects of virus biology, and replication of many, if not all, mammalian viruses can be suppressed by RNAi. Antiviral RNAi: Concepts, Methods, and Applications provides a collection of protocols for the analysis of viral small RNAs and natural antiviral RNAi responses as well as for the development and optimization of RNAi-based antiviral drugs. As RNAi is a central regulatory mechanism in... Viruses and RNAi share an intricate relationship at many levels. RNAi is an important antiviral defense mechanism in plants and invertebrates, micr... |
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605,23 |
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DNA Recombination: Methods and Protocols
ISBN: 9781617791284 / Angielski / Twarda / 580 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Homologous recombination is important in various aspects of DNA metabolism, including damage repair, replication, telomere maintenance, and meiosis, and yeast genetics has successfully provided a framework for the mechanism of homologous recombination. Divided into four convenient sections, DNA Recombination: Methods and Protocols covers recent techniques that best utilize the advantages of the yeast system, prescribing to the belief that yeast will keep serving as a great model organism to study homologous recombination. Chapters have also been included for such exceptions as the group of...
Homologous recombination is important in various aspects of DNA metabolism, including damage repair, replication, telomere maintenance, and meiosis, a...
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726,29 |
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Human Genetic Variation in Response to Medical and Environmental Agents: Pharmacogenetics and Ecogenetics: International Titisee Conference, Schwarzwa
ISBN: 9783540091752 / Angielski / Miękka / 194 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. |
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403,47 |
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Trisomy 21: An International Symposium Convento Delle Clarisse, Rapallo, Italy, November 8 - 10, 1979
ISBN: 9783540106531 / Angielski / Miękka / 268 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. With contributions by numerous experts
With contributions by numerous experts
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403,47 |
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Genregulation: Der Biologische Schalter Bei Phage ?
ISBN: 9783540502364 / Niemiecki / Miękka Termin realizacji zamówienia: ok. 5-8 dni roboczych. |
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301,67 |
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The Genetics of Diabetes Mellitus
ISBN: 9783540076513 / Angielski / Miękka / 250 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. On February 21 and 22, 1975, an International Workshop on the "Genetics of Diabetes Mellitus" was held in Gottingen, West-Germany. This workshop had been organized hy the Department of Medicine, University of Gottingen, and was generously sponsored by the Deutsche Forschungsgemeinschaft. Some forty geneticists and clinicians from Europe and N orth America, working in the field of diabetes both in man and laboratory animals, participated. The 25lectures presented at the workshop are now assembled for publication. Some of the animated discussion which followed the presentations has been...
On February 21 and 22, 1975, an International Workshop on the "Genetics of Diabetes Mellitus" was held in Gottingen, West-Germany. This workshop had b...
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201,72 |
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Rechtliche Regelung Der Embryonenforschung Im Internationalen Vergleich
ISBN: 9783540441519 / Niemiecki / Twarda / 277 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Zulassigkeit und Grenzen der Forschung mit menschlichen Embryonen werden auf internationaler Ebene intensiv und mit zum Teil sehr unterschiedlichen Ergebnissen diskutiert. Gleichzeitig rucken angesichts des sich entwickelnden Wettbewerbs die Unterschiede in den nationalen Regelungen zunehmend in den Vordergrund. Aus deutscher Sicht haben nicht zuletzt die Diskussionen um den Import embryonaler Stammzellen und der Erlass des Stammzellgesetzes den Blick auf konkrete Regelungen der Embryonenforschung im Ausland gelenkt. In dem vorliegenden Band werden die Regelungskonzepte zur Embryonen- und...
Zulassigkeit und Grenzen der Forschung mit menschlichen Embryonen werden auf internationaler Ebene intensiv und mit zum Teil sehr unterschiedlichen Er...
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320,51 |
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Neuromuskuläre Krankheiten
ISBN: 9783540506379 / Niemiecki / Miękka / 293 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Standardisierte medizinische Terminologie Nomenklatur der Muskelkrankheiten und des erregungs}berleitenden Apparats mit ihren Definitionen.
Standardisierte medizinische Terminologie Nomenklatur der Muskelkrankheiten und des erregungs}berleitenden Apparats mit ihren Definitionen.
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207,36 |
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Genetics of the Hungarian Population: Ethnic Aspects, Genetic Markers, Ecogenetics and Disease Spectrum
ISBN: 9783540535805 / Angielski / Miękka / 344 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. I am pleased to respond to the wish of the Editors, Drs A. Czeizel, H. G. Benk- mann and H. W. Goedde and write the Foreword to this book "Genetics ofthe Hun- garian population." This book represents the result of a fruitful international scientif- ic cooperation, an endeavour that has been forged and sustained in the midst of a number of difficulties. It bears ample testimony to the fact that the pursuit of science transcends national boundaries and barriers and to what can be achieved through international cooperation. It has now become possible, among other things, to present a more...
I am pleased to respond to the wish of the Editors, Drs A. Czeizel, H. G. Benk- mann and H. W. Goedde and write the Foreword to this book "Genetics of...
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403,47 |
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Transgenic Mouse Methods and Protocols
ISBN: 9781607619734 / Angielski / Twarda / 352 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. The generation of genetically modified mice is absolutely crucial to gene function studies today, primarily because mice are genetically similar to man and because gene function studies in mice are in the context of a whole organism, making them particularly useful. In Transgenic Mouse Methods and Protocols, Second Edition, expert research explore current advances in the field through detailed laboratory protocols. Chapters provide a general introduction outlining how to deal with mice and how to generate transgenic mouse models, explore the generation of conditional and induced knockout and...
The generation of genetically modified mice is absolutely crucial to gene function studies today, primarily because mice are genetically similar to ma...
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cena:
806,99 |
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The Nuclear Receptor Superfamily: Methods and Protocols
ISBN: 9781617379130 / Angielski / Miękka / 240 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Acting principally to control patterns of gene expression, nuclear receptors play vital roles during embryonic development and in the regulation of metabolic and reproductive functions in adult life, which proves this superfamily of ligand-activated transcription factors to be a crucial part of biological life. In The Nuclear Receptor Superfamily: Methods and Protocols, expert researchers describe a range of molecular, structural and cell biological techniques currently used to investigate the structure-function of nuclear receptors, together with experimental approaches that may lead to... Acting principally to control patterns of gene expression, nuclear receptors play vital roles during embryonic development and in the regulation of... |
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484,18 |
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Molecular Genetics: 4. Wissenschaftliche Konferenz Der Gesellschaft Deutscher Naturforscher Und Ärzte Berlin 1967
ISBN: 9783540042761 / Angielski / Miękka / 343 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. A small informal symposium on "Molecular Genetics" was organized by us on behalf of the "Gesellschaft Deutscher Naturforscher und Arzte" and took place in Berlin in October 1967. There were about 40 partici- pants from Europe and the United States. Molecular Genetics represents today an extraordinarily comprehensive research field. Therefore the organizers of the symposium had the choice either of limiting the meeting to a particular topic or of covering a wider selection of current problems. The latter alternative was chosen. The fields of research of the participants covered the broad range...
A small informal symposium on "Molecular Genetics" was organized by us on behalf of the "Gesellschaft Deutscher Naturforscher und Arzte" and took plac...
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cena:
201,72 |
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