Kategoria BISAC: Medical >> Genetics

In quest opera sono riportate le conoscenze piu aggiornate sulle indagini del DNA che sono comunemente utilizzate per l identificazione di autori di reati violenti nelle indagini criminali, per l attribuzione dell identita a resti umani ed a vittime di disastri di massa, per la ricostruzione di rapporti parentali nelle indagini di paternita. La monografia descrive la biologia dei diversi tipi di DNA che sono utilizzati a questo scopo i microsatelliti del DNA autosomico, il DNA mitocondriale, i microsatelliti del cromosoma Y - le loro applicazioni elettive, le procedure di repertazione e...

Insulin-like growth factors (IGFs), their binding proteins and their receptors play important roles in regulating growth, metabolism, proliferation and survival for many cells and tissues throughout lifespan in humans and other species. Circulating IGF1 is known to be an endocrine regulator, with metabolic effects related to, and partly convergent with, insulin signalling. IGF1 also mediates many of the growth promoting effects of GH, and there is an ongoing debate as to the relative contributions of endocrine-, vs locally-derived IGF1 for systemic growth. More recently however, it has...

Genetic Algorithms in Molecular Modeling is the first book available on the use of genetic algorithms in molecular design. This volume marks the beginning of an ew series of books, Principles in Qsar and Drug Design, which will be an indispensible reference for students and professionals involved in medicinal chemistry, pharmacology, (eco)toxicology, and agrochemistry. Each comprehensive chapter is written by a distinguished researcher in the field.

Through its up to the minute content, extensive bibliography, and essential information on software availability, this book...

• Authored by some of the foremost scientists in the field
• Provides up-to-date information and directions for future...

Advances in molecular genetics have led to the increasing availability of genetic testing for a variety of inherited disorders. While this new knowledge presents many obvious health benefits to prospective individuals and their families it also raises complex ethical and moral dilemmas for families as well as genetic professionals.

This book explores the ways in which genetic testing generates not only probabilities of potential futures, but also enjoys new forms of social, individual and professional responsibility. Concerns about confidentiality and informed consent involving...

Initially genetic disorders were all considered as rare diseases. At present, in the mid of 2009, the OMIM catalogue contains information on more than 12 000 entries of which about 2500 are available for clinical testing based on the identification of the responsible gene defect. However, altogether it has been estimated that about 8 percent of a population in the economically developed countries will during their lifetime suffer from a disease mainly as the result of their genetic constitution. Adding to that, it is estimated that all diseases have a genetic component, which will...

• Reactive species as intracellular messengers
• Redox regulation of cellular responses
• Clinical implications of redox signaling and antioxidant therapy