Fish lymphocystis disease virus (FLDV) has been tentatively classified as a separate genus of the iridovirus family. Iridoviruses were previously called icosahedral cytoplasmic deoxyriboviruses (ICDV). The Iridoviridae family contains four genera including lymphocystis disease virus (proposed name Lymphocystivirus, Willis, 1989 (1. FLDV is a causative agent of lymphocystis disease (LD) which frequently appears in Pleuronectidae (flatfish) such as Pleuronectes platessa (plaice), Platichtys flesus (flounder), Limanda limanda (dab), and Trigla gurnardus (gurnard). Fish lymphocystis disease is...

second gene is the endoplasmic reticulum (ER) elements (SINEs). The repetitive DNA sequences in resident heat shock protein GRP78, a member of the eukaryotic genomes are thought to reflect the Bip family. The identification of an ER resident evolutionary forces acting on selfish DNA (10). It GRP78 protein in G. lamblia, a primitive eukaryotic may be possible to suggest that the Archeabacterial "archazoan" that lacks mitochondria and other retrons (6) further evolved, by recruiting essential organelles, strongly suggests the existence of ER in cellular genes, into RNA and DNA viruses. this...

The influence of basic science, particularly molecular biology, in human and veterinary medicine revolutionized thinking in many aspects and changed fundamentally and creatively the classical strategy for research and prevention of infectious diseases. Genetic engineering and related disciplines have progressed to a remarkable degree over the last decade and now form the keystone supporting medicine. These are strong and efficient instruments for health and disease oriented research and their application gives the opportunity to receive more answers and not only more questions. The prime...

The basis for the effective treatment and cure of a patient is the rapid diagnosis of the disease and its causative agent, which is based on the analysis of the clinical symptoms coupled with laboratory tests. Although rapid advance ments have been made in the laboratory diagnosis of virus diseases, the neces sary isolation of the causative virus from the clinical specimens is a relatively long procedure. Viruses which integrate into the cellular DNA (such as human immunodeficiency virus, HIV -1, or hepatitis B virus) are difficult to identify by molecular techniques, while viruses which...

In this book the current knowledge on human cytomegalovirus (HCMV) as a human pathogen is lucidly summarized, bringing the reader fully up to date with current knowledge concerning HCMV and all the known clincial and medical aspects of diseases caused by, and associated with, HCMV. The book is divided into four parts: (I) Human cytomegalovirus and human diseases; (II) human cytomegalovirus infections and the immunocompromised host; (III) diagnosis, treatment, and prevention of human cytomegalovirus and human diseases; and (IV) molecular aspects of human cytomegalovirus. Each part is put...

The questions of how the pathogenic human herpesviruses cause diseases, and what should be done to prevent infection and disease have prompted scientific interest in the molecular basis of the functions of all human herpesvirus genes in various tissues and organs of the infected host. This volume compiles the knowledge on the pathogenicity genes of herpes simplex virus types 1 and 2, the ones which have been most actively investigated at the molecular level. It adds to the understanding of herpesvirus gene involvement in diseases and shows the potential of this knowledge for planning new...

second gene is the endoplasmic reticulum (ER) elements (SINEs). The repetitive DNA sequences in resident heat shock protein GRP78, a member of the eukaryotic genomes are thought to reflect the Bip family. The identification of an ER resident evolutionary forces acting on selfish DNA (10). It GRP78 protein in G. lamblia, a primitive eukaryotic may be possible to suggest that the Archeabacterial "archazoan" that lacks mitochondria and other retrons (6) further evolved, by recruiting essential organelles, strongly suggests the existence of ER in cellular genes, into RNA and DNA viruses. this...

Fish lymphocystis disease virus (FLDV) has been tentatively classified as a separate genus of the iridovirus family. Iridoviruses were previously called icosahedral cytoplasmic deoxyriboviruses (ICDV). The Iridoviridae family contains four genera including lymphocystis disease virus (proposed name Lymphocystivirus, Willis, 1989 (1. FLDV is a causative agent of lymphocystis disease (LD) which frequently appears in Pleuronectidae (flatfish) such as Pleuronectes platessa (plaice), Platichtys flesus (flounder), Limanda limanda (dab), and Trigla gurnardus (gurnard). Fish lymphocystis disease is...

The influence of basic science, particularly molecular biology, in human and veterinary medicine revolutionized thinking in many aspects and changed fundamentally and creatively the classical strategy for research and prevention of infectious diseases. Genetic engineering and related disciplines have progressed to a remarkable degree over the last decade and now form the keystone supporting medicine. These are strong and efficient instruments for health and disease oriented research and their application gives the opportunity to receive more answers and not only more questions. The prime...