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Dynamics and the Problem of Recognition in Biological Macromolecules
ISBN: 9781461376774 / Angielski / Miękka / 311 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. From within complex structures of organisms and cells down to the molecular level, biological processes all involve movement. Muscular fibers slide on each other to activate the muscle, as polymerases do along nucleic acids for replicating and transcribing the genetic material. Cells move and organize themselves into organs by recognizing each other through macromolecular surface-specific interactions. These recognition processes involve the mu- tual adaptation of structures that rely on their flexibility. All sorts of conformational changes occur in proteins involved in through-membrane...
From within complex structures of organisms and cells down to the molecular level, biological processes all involve movement. Muscular fibers slide on...
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The Molecular Genetics of Aging
ISBN: 9783642536861 / Angielski / Miękka / 240 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. The molecular genetics of aging or life-span determination is an expanding field. One reason is because many people would consider it desirable if hu man life span could be extended. Indeed, it is difficult not to be fascinated by tales of the life and death of people who have succeeded in living a very long life. Because of this, we have placed at the head of this book the chapter by Perls et al. on Centenerians and the Genetics of Longevity. Perls and his coauthors convincingly argue that, while the average life expectancy might be mostly determined by environmental factors because the...
The molecular genetics of aging or life-span determination is an expanding field. One reason is because many people would consider it desirable if hu ...
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Oxygen Free Radicals in Tissue Damage
ISBN: 9781461598428 / Angielski / Miękka / 297 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Oxygen free radicals and other reactive oxygen species are being postulated as causal agents in an increasing number of pathological conditions. Indeed, some investigators are suggesting that highly destructive reactive oxygen species are the final common path lead- ing to tissue damage following a wide variety of insults including trauma, hypoxia, ischemia, hyperoxia, radiation, some toxins, and even strenuous athletic pursuits. But, as Robert Floyd points out, "Proof of the importance of oxygen free radicals and the oxidative damage they initiate depend on unequivocal evidence for the pres-...
Oxygen free radicals and other reactive oxygen species are being postulated as causal agents in an increasing number of pathological conditions. Indee...
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The Application of Laser Light Scattering to the Study of Biological Motion
ISBN: 9781468444896 / Angielski / Miękka / 705 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Several previous Advanced Study Institutes have concentrated on the techniques of light scattering, while the biological appli- cations were not fully explored. Many of the techniques are now standardised and are being applied to a wide range of biologically significant problems both in vivo and in vitro. While laser light scattering methods are superior to conventional methods, there was a general reluctance among biologists to adopt them because of the complexity of the physical techniques and the accompanying mathe- matical analysis. Consequently valuable opportunities for advancing the...
Several previous Advanced Study Institutes have concentrated on the techniques of light scattering, while the biological appli- cations were not fully...
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Excitatory Amino Acids: From Genes to Therapy
ISBN: 9783662035986 / Angielski / Miękka / 210 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. In this book emerging questions of current glutamate research are addressed and new pathways which glutamte research may take in the future discussed. Since glutamate antagonists are still the major hope for the therapy of neurodegenerative disorders in humans, research activities dedicated towards the development of such novel drugs are the focus of public attention. The book comments on the most recent discoveries in the field of neuroprotection and neurodegeneration.
In this book emerging questions of current glutamate research are addressed and new pathways which glutamte research may take in the future discussed....
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Novel Approaches to Treatment of Osteoporosis
ISBN: 9783662090091 / Angielski / Miękka / 264 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Osteoporosis affects a growing number of the population. Current treatments are based on prevention of further bone loss after the condition is diagnosed, often because a fracture has occurred. Treatments in the future will aim at healing osteoporosis by improving bone mass and quality. This book describes novel discoveries and research which will allow bone to be restored after it has been lost.
Osteoporosis affects a growing number of the population. Current treatments are based on prevention of further bone loss after the condition is diagno...
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On Asking the Right Kind of Question in Biological Research: Neue Aussichten Für Die Pflanzenzüchtung: Gen-Übertragung Mit Dem Ti-Plasmid
ISBN: 9783531083001 / Angielski / Miękka / 56 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. |
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Correlation-Based Network Analysis of Cancer Metabolism: A New Systems Biology Approach in Metabolomics
ISBN: 9781493906147 / Angielski / Miękka / 61 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. With the rise of systems biology as an approach in biochemistry research, using high throughput techniques such as mass spectrometry to generate metabolic profiles of cancer metabolism is becoming increasingly popular. There are examples of cancer metabolic profiling studies in the academic literature; however they are often only in journals specific to the metabolomics community. This book will be particularly useful for post-graduate students and post-doctoral researchers using this pioneering technique of network-based correlation analysis. The approach can be adapted to the analysis of...
With the rise of systems biology as an approach in biochemistry research, using high throughput techniques such as mass spectrometry to generate metab...
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Cell Aging: Molecular Mechanisms and Implications for Disease
ISBN: 9783642451782 / Angielski / Miękka / 108 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Aging represents a physiological and per se non-pathological and multifactorial process involving a set of key genes and mechanisms being triggered by different endogenous and exogenous factors. Since aging is a major risk factor in connection with a variety of human disorders, it is increasingly becoming a central topic in biochemical and medical research. The plethora of theories on aging - some of which have been discussed for decades - are neither isolated nor contradictory but instead can be connected in a network of pathways and processes at the cellular and molecular levels.... Aging represents a physiological and per se non-pathological and multifactorial process involving a set of key genes and mechanisms being tr... |
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Amyloid Protein Precursor in Development, Aging and Alzheimer’s Disease
ISBN: 9783662011379 / Angielski / Miękka / 257 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. This volume contains the proceedings of the ninth "Colloque medecine et recherche" of the Fondation IPSEN devoted to research on Alzheimer's disease. This symposium was held in Lyon on June 21, 1993, on the topic, "Amyloid Protein Precursors in Development, Aging and Alzheimer's Disease." The choice of this venue and of this particular subject was not a matter of chance. As far as the history of medicine and neurology is concerned, Lyon is doubtless one of the most famous cities in France and the F ondation IPSEN had to organize one of its meetings in this city which has been regarded for...
This volume contains the proceedings of the ninth "Colloque medecine et recherche" of the Fondation IPSEN devoted to research on Alzheimer's disease. ...
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Micromethods in Molecular Biology
ISBN: 9783642807633 / Angielski / Miękka / 435 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. This book is based on practical experience and is therefore written as a prac tical manual. The fore-runners of the book were the manuals of the first and second EMBO-Courses on "Micromethods in Molecular Biology" which were held in G6ttingen in the spring of 1970 and the autumn of 1971. This book may serve as a manual not only for the participants of the third EMBO-Course to be held in G6ttingen in autumn 1973, but also for all experimenters who are interested in using micromethods. It must be emphasized from the outset that this book is conceived as a "cook book" and not as a monograph...
This book is based on practical experience and is therefore written as a prac tical manual. The fore-runners of the book were the manuals of the first...
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Cell Cycle and Cell Differentiation
ISBN: 9783662216934 / Angielski / Miękka / 331 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. It is instructive to compare the response of biologists to the two themes that comprise the title of this volume. The concept of the cell cycle-in contra distinction to cell division-is a relatively recent one. Nevertheless biologists of all persuasions appreciate and readily agree on the central problems in this area. Issues ranging from mechanisms that initiate and integrate the synthesis of chro mosomal proteins and DNA during S-phase of mitosis to the manner in which assembly of microtubules and their interactions lead to the segregation of metaphase chromosomes are readily followed by...
It is instructive to compare the response of biologists to the two themes that comprise the title of this volume. The concept of the cell cycle-in con...
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Genetic Mosaics and Cell Differentiation
ISBN: 9783662219522 / Angielski / Miękka / 318 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. The relationship of cell lineage and differentiation is one of the most intriguing problems in developmental biology. In most higher organisms, the analysis of the cell lineage has to rely on indirect methods. Only in the most suitable systems, like the nematodes, can the pattern of cell division be determined by direct observation under the microscope. In cases where this is not possible, the fate of the cells has to be examined by using cell markers. Most suitable for this purpose are genetic markers, provided that they do not interfere with the developmental pathway to be studied. However,...
The relationship of cell lineage and differentiation is one of the most intriguing problems in developmental biology. In most higher organisms, the an...
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Differentiation & Growth of Cells in Vertebrate Tissues
ISBN: 9780412113901 / Angielski / Miękka / 323 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. In recent years a new field of study has arisen called developmental biology. The term developmental biology is really a new name for embryology; it is, however, used to denote the molecular approach to the study of developing systems. In this book we have tried wherever possible to blend the older information of classical embryology and in particular organogeny with the newer concepts of developmental biology. The original intention was to cover all the tissues of the body in this book. However, it soon became obvious that it was not possible to do this within one volume. Therefore we...
In recent years a new field of study has arisen called developmental biology. The term developmental biology is really a new name for embryology; it i...
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Cellular Development
ISBN: 9780412114106 / Angielski / Miękka / 64 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. 1. 1. Aspects of development. usually competent to develop in several differ If you have been fortunate enough to see a fIlm ent ways. Thus the mesenchyme cells of the of the development of any multicellular organ embryonic chick limb bud may become, among ism or, better still, to watch live embyros devel other things, muscle or cartilage cells. Differen oping, the intricate beauty of the developmental tiation is largely an intracellular process involv process will not have escaped you: nor will its ing the appearance of cells with certain bio complexity. Apparent complexity, however, is...
1. 1. Aspects of development. usually competent to develop in several differ If you have been fortunate enough to see a fIlm ent ways. Thus the mesenc...
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Pulsed-Field Gel Electrophoresis: Protocols, Methods, and Theories
ISBN: 9781489943910 / Angielski / Miękka / 481 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. e1ectr0ph0re515 (PF6E) wa51nvented 6are1y 10 year5 a90, 6ut ha5 a1ready 6ec0me a maj0r techn14ue m01ecu- 610109y, 1ar w1th hundred5 0f 0ften the ca5e w1th new techn14ue5 the1r 5ta9e5, m05t pu611cat10n5 are 0- dated 6y the t1me they reach pr1nt. F0r rea50n, a num6er 0fthe auth0r5 0f 600k have effect1ve1y 5erved ph0ne c0n5u1tant5 0n PF6E app11cat10n5 f0r 5evera1 year5. 8y n0w, many 0f the maj0r meth0d5 have 6een te5ted and 1mpr0ved that we fee1 a 600k 0f techn14ue5 W0ve Dur1n9 the prepara- Meth0d5, and 7, tw0 0ther 600k5 rev1ew1n9 PF6E were pu6115hed. H0wever, the pre5ent w0rk the f1r5t t0...
e1ectr0ph0re515 (PF6E) wa51nvented 6are1y 10 year5 a90, 6ut ha5 a1ready 6ec0me a maj0r techn14ue m01ecu- 610109y, 1ar w1th hundred5 0f 0ften the ca5e ...
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Fingerprinting Methods Based on Arbitrarily Primed PCR
ISBN: 9783642478123 / Angielski / Miękka / 441 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. DNA and RNA fingerprinting based on arbitrarily primed PCR provides the most powerful tool for the study of genes.
The basic techniques are described in detailed protocols including each step from template preparation to fingerprint visualization. Various protocols for the basic techniques allow to choose between alternative strategies. In addition to the general techniques specific research applications of particular interest are given such as gene mapping, detection of somatic mutations, gene abnormally expressed in tumors or differentially expressed genes by RNA fingerprinting. DNA and RNA fingerprinting based on arbitrarily primed PCR provides the most powerful tool for the study of genes.
The basic techniques are describ... |
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Organellar Proton-ATPases
ISBN: 9783662222676 / Angielski / Miękka / 228 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. THE WORLD OF PROTON PUMPS Nathan Nelson uite frequently an observer looks at a life phenomenon and asks himself why nature took this route out of several other available mec anisms. In order to understand this challenge he may first try to reconstruct the evolution of the process taking into account the main driving forces that were assumed to exist during the last 3. 5 billion years on earth. Now we know that the electrochemical gradient of protons is the universal high-energy intermediate produced and uti lized by every living cell in nature. This high energy intermediate is an expression...
THE WORLD OF PROTON PUMPS Nathan Nelson uite frequently an observer looks at a life phenomenon and asks himself why nature took this route out of seve...
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Pre-mRNA Processing
ISBN: 9783662223277 / Angielski / Miękka / 221 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. he past fifteen years have seen tremendous growth in our understanding of T the many post-transcriptional processing steps involved in producing func tional eukaryotic mRNA from primary gene transcripts (pre-mRNA). New processing reactions, such as splicing and RNA editing, have been discovered and detailed biochemical and genetic studies continue to yield important new insights into the reaction mechanisms and molecular interactions involved. It is now apparent that regulation of RNA processing plays a significant role in the control of gene expression and development. An increased...
he past fifteen years have seen tremendous growth in our understanding of T the many post-transcriptional processing steps involved in producing func ...
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Reviews of Physiology, Biochemistry and Pharmacology
ISBN: 9783662309995 / Angielski / Miękka / 105 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Springer Book Archives
Springer Book Archives
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