» książki » Medical - Toxicology
 |
Zoonotic Pathogens in the Food Chain
ISBN: 9781845936815 / Angielski / Twarda / 256 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Examining the development, spread and transmission of zoonotic diseases through the food chain; from animals, through production processes to humans, this book discusses the ways modern food production systems contribute to the risk of zoonotic disease, and where mitigation strategies need to be focused.
Examining the development, spread and transmission of zoonotic diseases through the food chain; from animals, through production processes to humans, ...
|
cena:
655,53 |
 |
Biotransformation and Metabolite Elucidation of Xenobiotics: Characterization and Identification
ISBN: 9780470504789 / Angielski / Twarda / 344 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. The goal of this book is to improve the readers' knowledge of metabolite elucidation in drug metabolism by exposing them to in depth coverage of the biotransformation of xenobiotics, strategies for identifying and characterizing metabolites, FDA guidelines, and case studies on how to improve the decision-making process in structural modification of drug candidates to reduce toxicity.
The book consists of 8 chapters; it first provides an introduction on biotransformation of xenobiotics, and then presents modern approaches and strategies for dealing with metabolite characterization, using... The goal of this book is to improve the readers' knowledge of metabolite elucidation in drug metabolism by exposing them to in depth coverage of the b...
|
cena:
597,78 |
 |
An Overview on Toxigenic Fungi and Mycotoxins in Europe
ISBN: 9781402026454 / Angielski / Twarda / 268 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. The growing interest in health risks associated with toxigenic fungi and related mycotoxins has led to the development of a number of research projects during the past decade in several European countries and a great deal of information has been produced on the natural occurrence of mycotoxins in plants, foods and feeds. The differences in environmental conditions (temperature, light, rainfall etc. ) and in exposed cultivated plants (type of cereals, cultivars etc. ) in the distinct European countries have significantly influenced the distribution of specific toxigenic fungi and related...
The growing interest in health risks associated with toxigenic fungi and related mycotoxins has led to the development of a number of research project...
|
cena:
724,58 |
 |
Systems Biology in Drug Discovery and Development: Methods and Protocols
ISBN: 9781607617990 / Angielski / Twarda / 337 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Due to the failing "one-drug-fits-all" model, it has become increasingly necessary to develop personalized medicine that treats whole systems and brings the right drug to the right patient with the right dosages. In Systems Biology in Drug Discovery and Development: Methods and Protocols, leading experts provide a practical, state-of-the-art, and holistic view of the translation of systems biology into better drug discovery and personalized medical practice. While the first part of the book describes cutting-edge technologies and methods in the field, the second part illustrates how the...
Due to the failing "one-drug-fits-all" model, it has become increasingly necessary to develop personalized medicine that treats whole systems and brin...
|
cena:
402,53 |
 |
The Clinical Chemistry of Laboratory Animals
ISBN: 9781420091137 / Angielski / Twarda / 1162 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Edited in partnership with the American College of Laboratory Medicine (ACLAM), Loeb and Quimby's Clinical Chemistry of Laboratory Animals, Third Edition is the most comprehensive reference available on in vivo animal studies as a critical part of biomedical research. It covers relevant laboratory animal species, specific organ systems (hepatic, renal, etc.), and important classes of analytes (hormones, lipids, carbohydrates, etc.). The book also addresses additional organs not included in earlier editions such as cardiovascular/pulmonary; gastrointestinal and pancreas; and skeletal. The book...
Edited in partnership with the American College of Laboratory Medicine (ACLAM), Loeb and Quimby's Clinical Chemistry of Laboratory Animals, Third Edit...
|
cena:
930,57 |
 |
Advances in Microbial Toxin Research and Its Biotechnological Exploitation
ISBN: 9781441933843 / Angielski / Miękka / 288 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Microbial toxins are secondary metabolites that accumulate in the organism and, to a large extent, are metabolically inactive towards the organism that produces them. The discovery of penicillin, a secondary metabolite of Penicillium notatum West (= P. chrysogenum Thom), in 1929 marked a milestone in the development of antibiotics (microbial toxins). In the intensive studies that followed this discovery, scientists chemically characterized several new molecules (toxins) from secondary metabolites of microbes, some having a definite function in causing pathogenesis in plants. Toxins are also...
Microbial toxins are secondary metabolites that accumulate in the organism and, to a large extent, are metabolically inactive towards the organism tha...
|
cena:
603,81 |
 |
Bacterial Protein Toxins
ISBN: 9783642085406 / Angielski / Miękka / 700 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. In recent years remarkable progress has been accomplished with respect to our knowledge about bacterial protein toxins. This refers especially to structural aspects of protein toxins but also holds true for genetics, molecular biology and biochemical mechanisms underlying the action of toxins. This volume covers the very current and exciting aspects of up-to-date bacterial toxicology and comprehensively reviews the most important bacterial protein toxins such as the intracellular acting toxins which exhibit enzyme activity, as well as those toxins that interact with cell plasma membranes by...
In recent years remarkable progress has been accomplished with respect to our knowledge about bacterial protein toxins. This refers especially to stru...
|
cena:
2257,33 |
 |
Drug Metabolism and Transport: Molecular Methods and Mechanisms
ISBN: 9781617374944 / Angielski / Miękka / 388 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. A compendium of proven experimental approaches and strategies for studying the bioactivation, detoxification, tissue distribution, and elimination of xenobiotics in the metabolism and/or transport of various chemicals. The authors address several of the major drug metabolizing systems, including the cytochrome P450 family, flavin-containing monooxygenases, glutathione, S-transferase, glucuronidation, N-acetylation, and sulfotransferases. Additional chapters present novel approaches to the study of: signaling pathways in the regulation of drug metabolism enzymes, how the modulation of thiols...
A compendium of proven experimental approaches and strategies for studying the bioactivation, detoxification, tissue distribution, and elimination of...
|
cena:
603,81 |
 |
Methods in Biological Oxidative Stress
ISBN: 9781617372001 / Angielski / Miękka / 216 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Oxidative damage appears to play a central role in the development of a wide range of tissue pathology, including neurodegenerative disease, drug side-effects, xenobiotic toxicity, carcinogenesis, and the aging process, to name just a few. Because of the centrality of oxidative processes to normal and abnormal tissue function, it has become imperative to develop appropriate analytical techniques to facilitate the quantitation of significant reactants. Without advances in methodology, corresponding advances in our knowledge of underlying biochemical events will be necessarily limited. Drs....
Oxidative damage appears to play a central role in the development of a wide range of tissue pathology, including neurodegenerative disease, drug side...
|
cena:
402,53 |
 |
Chemical Analysis of Antibiotic Residues in Food
ISBN: 9780470490426 / Angielski / Twarda / 384 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. An insightful exploration of the key aspects concerning the chemical analysis of antibiotic residues in food
The presence of excess residues from frequent antibiotic use in animals is not only illegal, but can pose serious health risks by contaminating products for human consumption such as meat and milk. Chemical Analysis of Antibiotic Residues in Food is a single-source reference for readers interested in the development of analytical methods for analyzing antibiotic residues in food. It covers themes that include quality assurance and quality control, antibiotic chemical... An insightful exploration of the key aspects concerning the chemical analysis of antibiotic residues in food
The presence of excess residues... |
cena:
566,84 |
 |
Killer Clothes: How Clothing Choices Endanger Your Health
ISBN: 9781570672637 / Angielski / Miękka / 192 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. This book reveals in unprecedented detail the toxic truth about the clothes we wear and the surprising number of harmful effects on health caused by garments once considered safe. From toxic chemicals like formaldehyde and phthalates to insecticides, flame retardants, and nano-particles, synthetic clothing today contains a toxic stew of dozens of substances that pose a threat to both human and environmental health. You'll learn: what fabrics and chemicals to watch for when selecting clothing; how to identify deceptive synthetic fabrics; why to avoid clothing labeled antishrink, antibacterial,...
This book reveals in unprecedented detail the toxic truth about the clothes we wear and the surprising number of harmful effects on health caused by g...
|
cena:
65,32 |
 |
Recent Developments in Toxicology: Trends, Methods and Problems: Proceedings of the European Societies of Toxicology Meeting Held in Leipzig, Septembe
ISBN: 9783540514220 / Angielski / Miękka / 323 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. This volume of conference proceedings contains papers on the neurotoxicology of different noxious compounds, new aspects and methods in toxicopathology, cardiovascular toxicology, toxic effects on haemostasis, the liver and the kidney, and miscellaneous toxic effects.
This volume of conference proceedings contains papers on the neurotoxicology of different noxious compounds, new aspects and methods in toxicopatholog...
|
cena:
402,53 |
 |
Apoptosis Methods in Pharmacology and Toxicology: Approaches to Measurement and Quantification
ISBN: 9781617372391 / Angielski / Miękka / 156 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Dr. Myrtle A. Davis has assembled a panel of cutting-edge scientists to describe their best methods for detecting, illuminating, and quantifying apoptotic mechanisms in a way that is useful for the design of toxicology and pharmacology studies. These state-of-the-art techniques include flow cytometric, fluorometric, and laser scanning methods for quantifying and characterizing apoptosis, as well as protocols for the use of DNA microarray technology, high throughput screens, and ELISA. Immunocytochemical methods for measuring biochemical and molecular endpoints in tissue sections will be...
Dr. Myrtle A. Davis has assembled a panel of cutting-edge scientists to describe their best methods for detecting, illuminating, and quantifying apopt...
|
cena:
402,53 |
 |
Molecular Toxicology Protocols
ISBN: 9781617373473 / Angielski / Miękka / 489 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. A collection of cutting-edge techniques for analyzing genotoxic exposure and detecting the resulting biological effects-including endogenous metabolites-up to and including the development of cancer. The authors emphasize analytical methods that can be specifically applied to human populations and patients. Among the applications detailed are the analysis of interactions between such cellular macromolecules as DNA and proteins and chemical and physical agents, the assessment of medically relevant toxicity, and the characterization of genetic alterations induced in transgenic animals by in...
A collection of cutting-edge techniques for analyzing genotoxic exposure and detecting the resulting biological effects-including endogenous metabolit...
|
cena:
523,14 |
 |
Foodborne Diseases
ISBN: 9781617376146 / Angielski / Miękka / 540 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. In this book, leading authorities present a broad overview of the microbial pathogens and toxins associated with foodborne illness while discussing pathogenicity, clinical epidemiology, diagnosis, and treatment. The volume covers all the bacterial pathogens, viruses, protozoans, and parasites, as well as microbial toxins. Additionally, authors discuss pathogen control strategies and look toward future innovations in food safety technology.
In this book, leading authorities present a broad overview of the microbial pathogens and toxins associated with foodborne illness while discussing... |
cena:
827,64 |
 |
Toxicogenomics
ISBN: 9784431703440 / Angielski / Twarda / 228 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Toxicogenomics is a new multidisciplinary field concerned with elucidating how the entire genome is involved in biological responses of organisms exposed to environmental toxicants and stressors. Toxicogenomics combines information from studies of genomic-scale mRNA profiling by microarray analysis, cell-wide or tissue-wide protein profiling (proteomics), genetic susceptibility related to single nucleotide polymorphism, and computational models to understand the roles of gene-environment interactions. This book makes a valuable addition to the laboratory bookshelf of all scientists and...
Toxicogenomics is a new multidisciplinary field concerned with elucidating how the entire genome is involved in biological responses of organisms expo...
|
cena:
402,53 |
 |
The Minipig in Biomedical Research
ISBN: 9781439811184 / Angielski / Twarda / 662 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. The Minipig in Biomedical Research is a comprehensive resource for research scientists on the potential and use of the minipig in basic and applied biomedical research, and the development of drugs and chemicals. Written by acknowledged experts in the field, and drawing on the authors global contacts and experience with regulatory authorities and the pharmaceutical and other industries, this accessible manual ranges widely over the biological, scientific, and practical uses of the minipig in the laboratory. Its coverage extends from the minipig s origins, anatomy,... The Minipig in Biomedical Research is a comprehensive resource for research scientists on the potential and use of the minipig in ... |
cena:
979,55 |
 |
Ion Channel Localization
ISBN: 9781617372117 / Angielski / Miękka / 502 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Since the pioneering discoveries of Hodgkin, Huxley, and Katz, it has been clear that specific ion conductance pathways underlie electrical act- ity. Over the ensuing 50 years, there has been ever increasing, and occasi- ally explosive, changes in the scope of efforts to understand ion channel behavior. The introduction of patch clamp technology by Erwin Neher and Bert Sakmann about 20 years ago led to the realization of the great variety of novel ion channel species, and the subsequent revolution in cl- ing has revealed an even greater diversity of the underlying molecular entities. Today,...
Since the pioneering discoveries of Hodgkin, Huxley, and Katz, it has been clear that specific ion conductance pathways underlie electrical act- ity. ...
|
cena:
603,81 |
 |
Handbook of Copper Pharmacology and Toxicology
ISBN: 9781617372667 / Angielski / Miękka / 608 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Edward J. Massaro and a panel of leading biomedical researchers and clinical practitioners review, in-depth, the status of our current knowledge concerning the biochemistry of copper in general and its role in health and disease in particular. Drawing on the wealth of new information emerging from the molecular biology revolution, these experts survey the most important research areas of copper pharmacology and toxicology, including copper proteins and transport, copper toxicity and therapeutics, and copper metabolism and homeostasis. They also discuss the molecular pathogenesis of copper in...
Edward J. Massaro and a panel of leading biomedical researchers and clinical practitioners review, in-depth, the status of our current knowledge conce...
|
cena:
805,10 |
 |
Safety Pharmacology in Pharmaceutical Development: Approval and Post Marketing Surveillance
ISBN: 9781439845677 / Angielski / Twarda / 213 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Safety pharmacology is the evaluation and study of the pharmacological effects of a potential drug that are unrelated to the desired therapeutic effect. These effects often present a hazard particularly in individuals with compromised or limited organ system functions. Safety Pharmacology in Pharmaceutical Development: Approval and Post Marketing Surveillance, Second Edition covers safety pharmacology from the regulatory requirements down to the studies that must be done to justify them. Using the author s more than 30 years of direct experience, the book incorporates tricks... Safety pharmacology is the evaluation and study of the pharmacological effects of a potential drug that are unrelated to the desired therapeutic ef... |
cena:
881,59 |
Czytaj nas na:
KrainaKsiazek.PL - Księgarnia Internetowa
