Clostridium difficile has been recognized as the cause of a broad spectrum of enteric disease ranging from mild antibiotic-associated diarrhea to pseudomembranous colitis. This volume gives new insights into the microbiology, diagnostics and epidemiology of Clostridium difficile and describes recent strategies in treatment of diseases caused by this agent. Main parts of the volume are devoted to Clostridium difficile toxins A and B which are the major virulence factors. The molecular biology, biochemistry, pharmacology and cell biology of these toxins which are the...
Clostridium difficile has been recognized as the cause of a broad spectrum of enteric disease ranging from mild antibiotic-associated diarrhea ...
In recent years remarkable progress has been accomplished with respect to our knowledge about bacterial protein toxins. This refers especially to structural aspects of protein toxins but also holds true for genetics, molecular biology and biochemical mechanisms underlying the action of toxins. This volume covers the very current and exciting aspects of up-to-date bacterial toxicology and comprehensively reviews the most important bacterial protein toxins such as the intracellular acting toxins which exhibit enzyme activity, as well as those toxins that interact with cell plasma membranes by...
In recent years remarkable progress has been accomplished with respect to our knowledge about bacterial protein toxins. This refers especially to stru...
Clostridium difficile has been recognized as the cause of a broad spectrum of enteric disease ranging from mild antibiotic-associated diarrhea to pseudomembranous colitis. This volume gives new insights into the microbiology, diagnostics and epidemiology of Clostridium difficile and describes recent strategies in treatment of diseases caused by this agent. Main parts of the volume are devoted to Clostridium difficile toxins A and B which are the major virulence factors. The molecular biology, biochemistry, pharmacology and cell biology of these toxins which are the...
Clostridium difficile has been recognized as the cause of a broad spectrum of enteric disease ranging from mild antibiotic-associated diarrhea ...
Die Aufgaben des niedergelassenen Nervenarztes fUr die psychiatrische Forschung Wichtige psychiatrische Forschungsfragen, von denen einige im folgenden erlautert werden, konnen heute nur in Zusammen arbeit zwischen niedergelassenen Nervenarzten und Psychiatri schen Universitatskliniken bzw. wissenschaftlichen Institutionen gelost werden. Ein besonders wichtiges Forschungsgebiet fUr diese Zusammen Therapieforschung. Die langjahrigen Verschrei arbeit ist die bungsgewohnheiten der Nervenarzte in der Praxis konnen das Fundament fur die endgiiltige Wirkbeschreibung neuer Prapara te sein. Ein...
Die Aufgaben des niedergelassenen Nervenarztes fUr die psychiatrische Forschung Wichtige psychiatrische Forschungsfragen, von denen einige im folgende...
Recent advances in molecular biology have shown GTPases and phosphoproteins to be the paramount molecular switches utilized intracellularly in biological systems. The origins of the GTPase switch appear to be almost as ancient as life itself, and through evolution nature has adapted this switch to a variety of purposes. In this two-volume work a broad survey of the major classes of GTPases is presented. The role of GTPases in ensuring accuracy during protein translation, a new look at the trimeric G-protein cycle, the molecular function of ARF in vesicle coating, the emerging role of the...
Recent advances in molecular biology have shown GTPases and phosphoproteins to be the paramount molecular switches utilized intracellularly in biologi...
