Pharmacology and Pharmacokinetics
ISBN: 9781468420579 / Angielski / Miękka / 388 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. This collection of papers by leading pharmacokineticists and pharmacolo gists is the proceedings of a conference held at the John E. . Fogarty International Center for Advanced Study in the Health Sciences, National Institutes of Health, October 30 to November 1, 1972. As part of its advanced study program, the Center conducts workshops, seminars, and conferences on topics related to the biomedical interests of the Scholars-in Residence. Professor Torsten Teorell came to the Center in 1970 as one of the first Scholars. In 1971 and 1972, he spent several months at the Center devoting his...
This collection of papers by leading pharmacokineticists and pharmacolo gists is the proceedings of a conference held at the John E. . Fogarty Interna...
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389,98 zł |
Smooth Muscle
ISBN: 9781468427530 / Angielski / Miękka / 731 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. The study of the actions of drugs on smooth muscle has been a preoccupation of many pharmacologists almost from the beginning of the discipline. To a con- siderable degree, the development of theories to explain drug actions on smooth muscle has occurred somewhat independently of the development of our knowledge of the physiology, biochemistry, and biophysics of smooth muscle. This knowledge has developed rapidly in the past decade, and some of its consequences for our understanding of drug-receptor interactions in smooth muscle have not always been fully appreciated or accepted. One of the...
The study of the actions of drugs on smooth muscle has been a preoccupation of many pharmacologists almost from the beginning of the discipline. To a ...
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389,98 zł |
Methods Used in Adenosine Research
ISBN: 9781468448887 / Angielski / Miękka / 384 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. In their classic paper in 1929, Drury and Szent-Gyorgyi described a number of the important cardiovascular actions of adenosine. Another thirty years were to pass before the possible physiological role of adenosine in coronary vasodilation was studied by Berne and others. Since then, there has been a tremendous increase in research into the actions of adenosine. Workers from many disciplines have employed a wide variety of techniques, since adenosine is a product of and a substrate for a number of metabolic pathways, is transported into cells, and acts at discrete receptor sites to modulate...
In their classic paper in 1929, Drury and Szent-Gyorgyi described a number of the important cardiovascular actions of adenosine. Another thirty years ...
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389,98 zł |
Insulin, Insulin-Like Growth Factors, and Their Receptors in the Central Nervous System
ISBN: 9781468453829 / Angielski / Miękka / 358 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Traditionally, intercellular communication and the regulation of biological functions of the body have been considered the role of two major and distinct systems: the nervous system and the endocrine system. The classic nervous system transmitted its signal rapidly by using electrical currents, whereas the signals used by the endocrine system were hormones produced by endocrine glands which reached the target tissues via the blood stream. During the past few decades, it has become apparent that these systems of intercellular com munication are not distinct and the signal messenger molecules...
Traditionally, intercellular communication and the regulation of biological functions of the body have been considered the role of two major and disti...
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389,98 zł |
New Trends in Pharmacokinetics
ISBN: 9781468480559 / Angielski / Miękka / 456 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. The last decade or so has witnessed tremendous progress in methodology in the field of drug development in general and pharmacokinetics in particular. Clinical pharmacokinetics is using new tools for probing into the "black box" once being ac cessible only partly through experimental techniques and, mostly through mathemati cal and computer means. Development of computerized scanning, positron emission tomography (PET), stereoselectivity and other techniques are now enabling investi gators to have better pictures of the systems they are studying. Mathematical models through computer...
The last decade or so has witnessed tremendous progress in methodology in the field of drug development in general and pharmacokinetics in particular....
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389,98 zł |
Stimulus Properties of Drugs
ISBN: 9781475707908 / Angielski / Miękka / 222 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Behavioral pharmacology represents a relatively recent scientific enterprise, the development of which can be followed by plotting the publication of major conceptual papers, review articles, and books. Dews (1955), Sidman (1955), and Brady (1956) published some of the first methodologically significant papers, changing the way both psychologists and pharmacologists viewed the analysis of the behavioral actions of drugs. Dews and Morse (1961), Cook and Kelleher (1963), Gollub and Brady (1965), and Weiss and Laties (1969) kept the field abreast of major developments in the study of behavioral...
Behavioral pharmacology represents a relatively recent scientific enterprise, the development of which can be followed by plotting the publication of ...
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389,98 zł |
Prostacyclin and Its Receptors
ISBN: 9781475781823 / Angielski / Miękka / 310 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. In addition to its well known anti-platelet and hypotensive properties, prostacyclin activates neuronal receptors in the central, enteric and sensory nervous systems. This volume discusses the properties of prostacyclin receptors in the cardiovascular and nervous systems, as well as in cells involved in inflammatory reactions. The chemistry and pharmacology of prostacyclin mimetics are also explored, higlighting their therapeutic value.
In addition to its well known anti-platelet and hypotensive properties, prostacyclin activates neuronal receptors in the central, enteric and sensor...
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389,98 zł |
Fluoroquinolone Antibiotics
ISBN: 9783034894371 / Angielski / Miękka / 261 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Since the introduction of ciprofloxacin in 1987, fluoroquinolones have expanded far beyond their early role in the treatment of urinary tract infections. Clinical applications beyond genitourinary tract infections include upper and lower respiratory infections, gastrointestinal infections, gynecologic infec- tions, sexually transmitted diseases, and some skin and soft tissue infections. Their ease of administration, favorable pharmacokinetic properties, excellent tolerability, and efficacy give them enormous potential for use and misuse alike. Quinolones have few common adverse effects, most...
Since the introduction of ciprofloxacin in 1987, fluoroquinolones have expanded far beyond their early role in the treatment of urinary tract infectio...
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389,98 zł |
Anxiolytics
ISBN: 9783034895811 / Angielski / Miękka / 181 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. For over thirty years the benzodiazepines monopolised not only the anxiolytic market but also clinical and animal research in anxiety. Indeed many animal tests developed since the 1960s have been optimised for the benzodiazepines and some programmes have even screened candidates as potential anxiolytics on their benzodiazepine-like side-effects rather than their anxiolytic activity. With the realisation of the drawbacks of the benzodiazepines, namely their potential for tolerance and dependency, there has been a renewed interest in alternative anxiolytics both from existing drugs such as the...
For over thirty years the benzodiazepines monopolised not only the anxiolytic market but also clinical and animal research in anxiety. Indeed many ani...
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389,98 zł |
Cognitive Enhancing Drugs
ISBN: 9783034896030 / Angielski / Miękka / 203 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. During the past decade research into the pharmacology of cognition, particularly regarding learning and memory, has supported the concept that many potential neural targets exist for the development of cognitive-enhancing drugs. Whereas the main impetus for this research has been the ever growing population of individuals with dementing disorders such as Alzheimers disease, attention is also being focused on issues relating to cognitive impairment associated with "normal" aging. This book is useful as a source of information for making informed decisions regarding the relative utility and... During the past decade research into the pharmacology of cognition, particularly regarding learning and memory, has supported the concept that many... |
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389,98 zł |
Experimental Production of Diseases: Heart and Circulation
ISBN: 9783642454691 / Angielski / Miękka / 602 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Springer Book Archives
Springer Book Archives
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389,98 zł |
Obesity: Pathology and Therapy
ISBN: 9783642640704 / Angielski / Miękka / 503 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Obesity is a serious medical problem that affects millions of people, especially in Western societies. Although long considered a complicating factor in a variety of diseases, there is now widespread agreement that obesity itself should be classified and treated as a disease and that it has important conse- quences for personal health, quality of life and cost to society. Understanding obesity and the means of treating it have been hampered in the past. There have been misperceptions that obesity is a behavioral disorder and that its treatments provides only cosmetic benefits. Pharmacologic...
Obesity is a serious medical problem that affects millions of people, especially in Western societies. Although long considered a complicating factor ...
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389,98 zł |
Antithrombotics
ISBN: 9783642641909 / Angielski / Miękka / 485 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. An up-to-date overview of blood coagulation, hemostatis, and thrombosis, this volume also provides a state-of-the-art report of current anti-thrombotic and anti-coagulant strategies as well as a summary of current research interest in the area and potential future targets. It attempts to balance traditional pharmacology with the newer sciences of molecular biology and in so doing, sets a framework for future advances in the field. The book is a concise, current and useful reference for the basic researcher as well as the practicing physician working in the fields of cardiology, internal...
An up-to-date overview of blood coagulation, hemostatis, and thrombosis, this volume also provides a state-of-the-art report of current anti-thromboti...
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389,98 zł |
Platelets and Their Factors
ISBN: 9783642644887 / Angielski / Miękka / 753 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Platelets playa fundamental, life-saving role in hemostasis and blood clotting at sites of vascular injury. Unwanted platelet activation and arterial thombus formation are, however, implicated in the onset of myocardial infarction, stroke, and other cardiovascular diseases. Acceptance that platelets play a major role in the pathogenesis of atherosclerosis including coronary heart disease has revolutionized the pharmacological treatment of cardiovascular diseases, and aspirin is now an essential antiplatelet drug and the golden standard for future developments. Yet the search for better and...
Platelets playa fundamental, life-saving role in hemostasis and blood clotting at sites of vascular injury. Unwanted platelet activation and arterial ...
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389,98 zł |
Pharmacological Aspects of Drug Dependence: Toward an Integrated Neurobehavioral Approach
ISBN: 9783642646317 / Angielski / Miękka / 658 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. In spite of a "war on drugs" that spans years, and in spite of increases in law enforcement efforts and to a lesser extent treatment, substance abuse and dependence continue. While the number of people who experiment with drugs has decreased in recent years, those who use drugs repeatedly, per- haps several times a week, a measure of "hard core" drug abusers, has not changed, and emergency room visits associated with substances abuse continues to rise. Considering both licit and illicit drug abuse, the number of drug abusers in, for example, the United States is very large and, accordingly,...
In spite of a "war on drugs" that spans years, and in spite of increases in law enforcement efforts and to a lesser extent treatment, substance abuse ...
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389,98 zł |
Adrenergic Activators and Inhibitors: Part II
ISBN: 9783642675867 / Angielski / Miękka / 938 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Springer Book Archives
Springer Book Archives
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Cyclic Nucleotides: Part II: Physiology and Pharmacology
ISBN: 9783642683954 / Angielski / Miękka / 888 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Cyclic nucleotides are intimately involved in the consequences of either stimulation or blockade of receptors; therefore, an understanding of the biochemistry of cyclic nucleotides ought to be important for pharmacologists. Pharmacology is a science that among other things investigates chemical compounds that affect the physiology of cells, tissues and organs. Frequently pharmacologists account for the effect of low concentrations of a drug upon a tissue by invoking the presence of a receptor upon the surface of the cell. Traditional pharmacologists excelled at identifying and classifying the...
Cyclic nucleotides are intimately involved in the consequences of either stimulation or blockade of receptors; therefore, an understanding of the bioc...
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389,98 zł |
Antiepileptic Drugs
ISBN: 9783642695209 / Angielski / Miękka / 867 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Epileptic disorders need treatment for many years or even for life, and this makes a thorough understanding of the pharmacokinetics and possible hazards and side effects of the drugs used in treatment mandatory. During recent decades our knowledge in this field has considerably increased, not least as a result of the development of specific and sensitive methods for the determination of anti- epileptic agents in biological material. The clinical pharmacology of this group of drugs has been studied extensively and can today be regarded as well established. This does not necessarily mean that...
Epileptic disorders need treatment for many years or even for life, and this makes a thorough understanding of the pharmacokinetics and possible hazar...
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389,98 zł |
Clinical Pharmacology of Antianginal Drugs
ISBN: 9783642695261 / Angielski / Miękka / 552 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. When I was asked some years ago by the editors of the Handbook of Experimental Pharmacology to edit a new volume on Antianginal Drugs, I agreed on the condition that, in accordance with my scientific background, primary emphasis be given to clinical pharmacology and therapeutics. It soon turned out that, due to rapid developments in this field, nothing of the previous volume on Antianginal Drugs by Charlier (Vol. 31, 1971) could be retained apart from its basic idea of devoting considerable space to methodology. Since editors must operate within certain limits, I had to abstain from dealing...
When I was asked some years ago by the editors of the Handbook of Experimental Pharmacology to edit a new volume on Antianginal Drugs, I agreed on the...
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389,98 zł |
Cardiovascular Effects of Dihydropyridine-Type Calcium Antagonists and Agonists
ISBN: 9783642705014 / Angielski / Miękka / 511 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Held at Boppard, Germany, October 3-6, 1984
Held at Boppard, Germany, October 3-6, 1984
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