Kategoria BISAC: Science >> Research & Methodology

Principles of Scientific Methods focuses on the fundamental principles behind scientific methods. The book refers to "science" in a broad sense, including natural science, physics, mathematics, statistics, social science, political science, and engineering science. A principle is often abstract and has broad applicability while a method is usually concrete and specific. The author uses many concrete examples to explain principles and presents analogies to connect different methods or problems to arrive at a general principle or a common notion. He mainly discusses a...

As microarray technology has matured, data analysis methods have advanced as well. Methods Of Microarray Data Analysis III is the third book in this pioneering series dedicated to the existing new field of microarrays. While initial techniques focused on classification exercises (volume I of this series), and later on pattern extraction (volume II of this series), this volume focuses on data quality issues. Problems such as background noise determination, analysis of variance, and errors in data handling are highlighted.

Three tutorial papers are presented to...

Animal Cell Biotechnology: Methods and Protocols, Third Edition constitutes a comprehensive manual of state-of-the-art and new techniques for setting up mammalian cell lines for production of biopharmaceuticals, and for optimizing critical parameters for cell culture from lab to final production. The volume is divided into five parts that reflect the processes required for different stages of production. In Part I, basic techniques for establishment of production cell lines are addressed, especially high-throughput synchronization, insect cell lines, transient gene and protein...

A collection of new reviews and protocols from leading experts in cell cycle regulation, Cell Cycle Control: Mechanisms and Protocols, Second Edition presents a comprehensive guide to recent technical and theoretical advancements in the field. Beginning with the overviews of various cell cycle regulations, this title presents the most current protocols and state-of-the-art techniques used to generate latest findings in cell cycle regulation, such as protocols to analyze cell cycle events and molecules. Written in the successful Methods in Molecular Biology series format,...

It is clear that hydraulic research is developing beyond traditional civil engineering to satisfy increasing demands in natural hazards assessment and also environmental research. Our ability to describe processes in nature rests on the observation and experimental methods as well as on theoretical basics of various disciplines. Under such conditions experimental methods draw from various areas of human activities and research, i.e. from physics, biology, chemistry, aerospace research, oceanic research etc. The current volume is the result of a meeting that took place during the 30th...

This book is written for ecologists interested in capturing their understandings of how natural systems work in software - to help inform their work and communicate the consequences of proposed management plans. Historically, ecologists had to rely on the skills of trained computer programmers to modeling natural systems, but now a new generation of software is allowing ecologists to directly capture their understandings of systems in software. This book is a compilation of spatially explicit simulation models developed by ecologists and planners without any formal computer programming...

Reflecting over three decades of advances, Epidermal Cells: Methods and Protocols, Third Edition underscores these advances in our understanding of epidermal biology with updated and entirely new protocols that compliment and extend the earlier edition. The inclusion of protocols useful for both in vitro and in vivo studies reflects many useful developments in the field. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily...

Why should researchers be interested in their feelings and emotions as they carry out research? Emotion is what it is to exist, to be human, and is present in every sphere of our lives. All activities are infused with emotion, even those that are constructed as rational, because rationality and emotionality are interpenetrated and entwined because all thinking is tinged with feeling, and all feeling is tinged with thinking.

This book illuminates the emotional processes of doing social and organizational research, and the implications of this for the outcomes of research. With...

Regulatory B Cells: Methods and Protocols present the current experimental set-ups and methodologies useful for the identification and characterization of B cells with suppressive functions and for the study of their biological and immunological properties. Organized into four sections, this detailed volume covers the basic methods for the isolation and immunophenotypical characterization of specific B cell subsets from mouse and human tissues, methods for the investigation of the mechanisms of immune suppression operated by B cells, several experimental approaches for the ex vivo...

Molecular Modeling of Proteins, Second Edition provides a theoretical background of various methods available and enables non-specialists to apply methods to their problems by including updated chapters and new material not covered in the first edition. This detailed volume opens by featuring classical and advanced simulation methods as well as methods to set-up complex systems such as lipid membranes and membrane proteins and continues with chapters devoted to the simulation and analysis of conformational changes of proteins, computational methods for protein structure prediction,...