NOTE: Annals volumes are available...

The information presented may help facilitate future collaborative studies that will lead to new insights into the pathogenesis of cardiopulmonary diseases...

Key Features:

• Explores current research linking aging, age-related diseases, neurodegeneration, and cancer.
• Includes papers presented at 13th...

This book is ideal for Graduate students, medical students, researchers and clinicians in with an interest in anatomy, physiology, developmental biology,...

For a long time, enzymes have been studied by measuring their activity, which has led to the advancement of "enzyme kinetics." In recent years, the mechanism of enzyme reaction has been explained in detail on the basis of the 3D structure. Genetic engineering and the 3D structural analysis of enzymes contribute to these advancements in enzymology. This book starts with an introduction to various enzymes to show how interesting enzymes are, which is followed by historical kinetic studies on enzymes and the overall and rapid-reaction kinetics. The subsequent topics describe the basics of...

• Genetic engineering
• Genetic manipulation
• Bioprocessing and fermentation
• Using microbes for producing

Ion channels are membrane proteins that act as gated pathways for the movement of ions across cell membranes. They play essential roles in the physiology of all cells. In recent years, an ever-increasing number of human and animal diseases have been found to result from defects in ion channel function. Most of these diseases arise from mutations in the genes encoding ion channel proteins, and they are now referred to as the channelopathies.

Ion Channels and Disease provides an informative and up-to-date account of our present understanding of ion channels and the molecular...

• Provides perspectives from both prokaryotic and eukaryotic systems
• Offers a timely, comprehensive review of mRNA degradation, its regulation, and its significance in the control of gene expression
• Discusses the mechanisms, RNA structural...

Membrane permeability is fundamental to all cell biology and subcellular biology. The cell exists as a closed unit. Import and export depend upon a number of sophisticated mechanisms, such as active transport, endocytosis, exocytosis, and passive diffusion. These systems are critical for the normal housekeeping physiological functions. However, access to the cell is also taken advantage of by toxic microbes (such as cholera or ptomaine) and when designing drugs.

Ernest Overton, one of the pioneers in lipid membrane research, put forward the first comprehensive theory of lipid...