Pharmacology of G Protein Coupled Receptors: Volume 62
ISBN: 9780123859525 / Angielski / Twarda / 408 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych (dostawa przed świętami) G protein coupled receptors remain the most important class of therapeutic targets in medicine. In the last 5 years, tremendous advances have been made in our understanding of the structure and mechanism of this critical family of drug targets. The present volume explores the modern experimental and conceptual framework for drug discovery for G protein coupled receptors. It explores advances in structure determination and structure-based drug design as well as new concepts of allosteric modulation, functional selectivity/biased agonism, and pharmacological chaperones. In addition, emerging... G protein coupled receptors remain the most important class of therapeutic targets in medicine. In the last 5 years, tremendous advances have been ... |
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1629,62 zł |
Integrins: Molecular and Biological Responses to the Extracellular Matrix
ISBN: 9780121711603 / Angielski / Twarda / 278 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych (dostawa przed świętami) Integrins: Molecular and Biological Responses to the Extracellular Matrix will help basic, applied, and clinical researchers keep up with the explosion of literature on the integrin family of proteins. This volume extends material previously covered in Receptors for Extracellular Matrix. It addresses some of the most exciting areas of integrin biology, including the varied roles of integrins in cell division, differentiation, movement, wound healing, inflammation, thrombosis, osteoporosis, and cancer.
Integrins: Molecular and Biological Responses to the Extracellular Matrix will help basic, applied, and clinical researchers keep up with the e...
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1659,68 zł |
Structure-Function Analysis of G Protein-Coupled Receptors
ISBN: 9780471252283 / Angielski / Twarda / 432 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych (dostawa przed świętami) G protein-coupled receptors (GPCRs) are the largest single class of receptors in biology, often playing key roles in a remarkably large number of physiological and pathophysiological conditions. GPCRs or GPCR-dependent signalling pathways are the targets of a very large number of therapeutically useful drugs. Detailed knowledge about the molecular structure of GPCRs should therefore pave the way for the design of novel drugs with increased efficacy and specificity.
This volume provides a concise, up-to-date presentation of methods (including molecular genetic, biochemical, and... G protein-coupled receptors (GPCRs) are the largest single class of receptors in biology, often playing key roles in a remarkably large number of phys...
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1682,39 zł |
Membrane Fusion
ISBN: 9780824783013 / Angielski / Twarda / 938 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych (dostawa przed świętami) A broad overview of recent progress in membrane fusion research, treating the subject from the fields of biophysics, biochemistry, cell biology, virology, and biotechnology. Featuring sections on the general properties of membranes and applications of membrane fusion techniques, this sourcebook outl
A broad overview of recent progress in membrane fusion research, treating the subject from the fields of biophysics, biochemistry, cell biology, virol...
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1692,26 zł |
Permeability and Stability of Lipid Bilayers
ISBN: 9780849345319 / Angielski / Twarda / 288 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych (dostawa przed świętami) This book presents a comprehensive and coherent picture of how molecules diffuse across a liquid that is, on average, only two molecules thick. It begins by characterizing bilayers structurally, using X-ray diffraction, and then mechanically by measuring elastic moduli and mechanisms of failure. Emphasis is placed on the stability and mechanical properties of plant membranes that are subject to very large osmotic and thermal stresses. Using this information, the transport of molecules of increasing complexity across bilayers is analyzed.
This book presents a comprehensive and coherent picture of how molecules diffuse across a liquid that is, on average, only two molecules thick. It beg...
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1692,26 zł |
The Amphipathic Helix
ISBN: 9780849349263 / Angielski / Twarda / 416 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych (dostawa przed świętami) A comprehensive volume discussing amphipathic helices in systems as diverse as serum lipoproteins, lung surfactant, cytotoxic peptides, ion channels, and mitochondrial targeting. It also includes general introductory material that defines amphipathic helices, and discusses methods to identify amphipathic helical segments.
A comprehensive volume discussing amphipathic helices in systems as diverse as serum lipoproteins, lung surfactant, cytotoxic peptides, ion channels, ...
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1692,26 zł |
Immune Modulating Agents
ISBN: 9780824701031 / Angielski / Twarda / 576 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych (dostawa przed świętami) Offers examinations of the pathways and agents that affect the human immune response, and provides presentations on practical methods of immune modulation. The text focuses on the immune response and modulation in infectious disease, such as HIV, hepatitis and parasitic infections, and highlights immune modulating agents in gastrointestinal diseases, sepsis, cancer and autoimmunity.
Offers examinations of the pathways and agents that affect the human immune response, and provides presentations on practical methods of immune modula...
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1692,26 zł |
Growth Control During Cell Aging
ISBN: 9780849345807 / Angielski / Twarda / 280 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych (dostawa przed świętami) The purpose of this book is to provide information on senescent cells and why they are prevented from multiplying via cell division. It includes main sections on the nature of Go/1 transition, factors promoting the cell cycle traverse and avoiding the Go/1 arrest, and negative factors arresting the cell cycle traverse and promoting the stay in the Go/1 stage. Filled with illustrations and explanations, it collectively presents the mechanisms that control the cellular aging process. This reference is a must for anyone with special interests in the biological community, and specifically the...
The purpose of this book is to provide information on senescent cells and why they are prevented from multiplying via cell division. It includes main ...
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1692,26 zł |
Alkali Cation Transport Systems in Prokaryotes
ISBN: 9780849369827 / Angielski / Twarda / 464 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych (dostawa przed świętami) Alkali Cation Transport Systems in Prokaryotes is the first book that brings together the physiological, structural, and molecular biological aspects of the transport of sodium, potassium, and ammonium across the bacterial cell membrane. Sodium translocation plays a major role in energy coupling of some prokaryotes, and much of the book is devoted to new and exciting developments in this field. Over 30 experts have contributed to this excellent reference for microbiologists, biochemists, molecular biologists, cell biologists, chemotherapists, and researchers interested in bioenergetics.
Alkali Cation Transport Systems in Prokaryotes is the first book that brings together the physiological, structural, and molecular biological aspects ...
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1692,26 zł |
Kaplan's Principles of Plant Morphology
ISBN: 9781482245196 / Angielski / Twarda / 1305 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych (dostawa przed świętami) The principles of plant morphology are being brought into studies of crop development, biodiversity and evolution during climate change, and researchers are in need of a modern reference and textbook on the subject. This book defines the field of plant morphology, providing resources, examples and theoretical constructs that illuminate the foundations of plant morphology and clearly outline the importance of integrating a fundamental understanding of plant morphology into modern research in plant genetics, development and physiology. The principles of plant morphology are being brought into studies of crop development, biodiversity and evolution during climate change, and resear... |
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1692,26 zł |
Handbook of Cell Signaling
ISBN: 9780123741455 / Angielski / Mixed media product / 3048 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych (dostawa przed świętami) KEY FEATURES:
* Contains over 350 chapters of comprehensive coverage on cell signaling * Includes discussion on topics from ligand/receptor interactions to organ/organism responses * Provides user-friendly, well-illustrated, reputable content by experts in the field DESCRIPTION: Handbook of Cell Signaling, Three-Volume Set, 2e, is a comprehensive work covering all aspects of intracellular signal processing, including extra/intracellular membrane receptors, signal transduction, gene expression/translation, and cellular/organotypic signal responses. The second edition is an... KEY FEATURES:
* Contains over 350 chapters of comprehensive coverage on cell signaling * Includes discussion on topics from ligand/receptor in... |
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1718,29 zł |
Cellular and Molecular Biology of Bone
ISBN: 9780125202251 / Angielski / Twarda / 567 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych (dostawa przed świętami) Written by well-known experts in their respective fields, this book synthesizes recent work on the biology of bone cells at the molecular level. Cellular and Molecular Biology of Bone covers the differentiation of these cells, the regulation of their growth and metabolism, and their death resorption. The authors' special comprehensive treatment of the cellular and molecular mechanisms of bone metabolism makes this book a unique and valuable tool. Cellular and Molecular Biology of Bone provides interested readers-with concise state-of-the-art reviews in bone biology that will...
Written by well-known experts in their respective fields, this book synthesizes recent work on the biology of bone cells at the molecular level. Ce...
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1719,81 zł |
Apoptosis and Beyond: The Many Ways Cells Die
ISBN: 9781119432425 / Angielski / Twarda / 784 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych (dostawa przed świętami) This three-volume source on apoptosis is the first, comprehensive collection to cover all of the known processes that cells undergo when they die. It is also the only one of its kind to compare these processes.
This three-volume source on apoptosis is the first, comprehensive collection to cover all of the known processes that cells undergo when they die. It ...
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1726,24 zł |
Mitochondria: Structure, Functions & Dysfunctions
ISBN: 9781616683467 / Angielski / Twarda / 1042 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych (dostawa przed świętami) Reviews research on the mitochondrial metabolism in age-related neurodegenerative disorders such as Alzheimer's and Parkinson's disease, mitochondria and ageing, apoptosis and peritoneal injury, and, diabetes, mitochondria and brain endothelium dysfunction as a dangerous triad for neurodegeneration.
Reviews research on the mitochondrial metabolism in age-related neurodegenerative disorders such as Alzheimer's and Parkinson's disease, mitochondria ...
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1822,38 zł |
Handbook of Free Radicals: Formation, Types & Effects
ISBN: 9781608761012 / Angielski / Twarda / 642 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych (dostawa przed świętami) Free radicals are molecules, ions, or atoms with unpaired electrons in their outermost shell of electrons. This book reviews the knowledge on free radicals and its possible mechanisms in neurological disorders and in some oxidative stress processes, such as in intractable epilepsy and febrile seizures.
Free radicals are molecules, ions, or atoms with unpaired electrons in their outermost shell of electrons. This book reviews the knowledge on free rad...
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1822,38 zł |
Handbook of Molecular Chaperones: Roles, Structures & Mechanisms
ISBN: 9781608763665 / Angielski / Twarda / 567 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych (dostawa przed świętami) Molecular chaperones are a ubiquitous class of proteins that play important roles in protein folding and in the protection of cells from several stresses associated with the disruption of three native dimensional structures of proteins. This book examines some of the biological aspects of this intriguing family of proteins.
Molecular chaperones are a ubiquitous class of proteins that play important roles in protein folding and in the protection of cells from several stres...
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1822,38 zł |
Replication and Transcription of Chromatin
ISBN: 9780849368035 / Angielski / Twarda / 288 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych (dostawa przed świętami) Replication and Transcription of Chromatin summarizes the main structural features of chromatin and presents results on replication and transcription gained over the last 20 years. The book emphasizes DNA-histone complexes and their importance in restricting genetic information encoded in DNA. Figures are used to illustrate many of the most important concepts of chromatin replication and transcription, and promising hypotheses and models are discussed to promote further research. Replication and Transcription of Chromatin is an important reference for biochemists, biophysicists, molecular...
Replication and Transcription of Chromatin summarizes the main structural features of chromatin and presents results on replication and transcription ...
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1822,43 zł |
Cryopreservation of Plant Cells and Organs
ISBN: 9780849361029 / Angielski / Twarda / 288 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych (dostawa przed świętami) |
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1822,43 zł |
Eosinophils in Allergy and Inflammation
ISBN: 9780824791216 / Angielski / Twarda / 528 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych (dostawa przed świętami) This work presents the proceedings of a conference held at Adare Manor, County Limerick, Ireland. It provides an updated, in-depth review of the biological role of eosinophils in allergic diseases, summarizing basic knowledge of these unique cationic proteins. The book features an annotated discussion of the conference's post-presentation question-and-answer session.
This work presents the proceedings of a conference held at Adare Manor, County Limerick, Ireland. It provides an updated, in-depth review of the biolo...
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1822,43 zł |
Physiology and Function of Glial Cells in Health and Disease
ISBN: 9781668496756 / Twarda / 320 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych (dostawa przed świętami) |
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1856,30 zł |