![]() |
Lead-Seeking Approaches
ISBN: 9783642010743 / Angielski / Twarda / 217 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. High quality leads provide the foundation for the discovery of successful clinical development candidates, and therefore the identi?cation of leads is an essential part of drug discovery. The process for the identi?cation of leads generally starts with the screening of a compound collection, either an HTS of a relatively large compound collection (hundreds of thousands to one million plus compounds) or a more focused screen of a smaller set of compounds that have been preselected for the target of interest. Virtual screening methods such as structure-based or pharmacophore-based searches can...
High quality leads provide the foundation for the discovery of successful clinical development candidates, and therefore the identi?cation of leads is...
|
cena:
603,81 |
![]() |
Educational Media and Technology Yearbook: Volume 34, 2009
ISBN: 9780387096742 / Angielski / Twarda / 592 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. The Educational Media and Technology Yearbook has become a standard reference in many libraries and professional collections. Examined in relation to its comp- ion volumes of the past, it provides a valuable historical record of current ideas and developments in the ?eld. Part I, Trends and Issues, presents an array of chapters that develop some of the current themes listed above, in addition to others. Part II, Library and Information Science, concentrates upon chapters of special relevance to K-12 education, library science education, school learning resources, and various types of library...
The Educational Media and Technology Yearbook has become a standard reference in many libraries and professional collections. Examined in relation to ...
|
cena:
603,81 |
![]() |
Model Systems in Catalysis: Single Crystals to Supported Enzyme Mimics
ISBN: 9780387980416 / Angielski / Twarda / 526 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. This book is an excellent compilation of cutting-edge research in heterogeneous catalysis and related disciplines - surface science, organometallic catalysis, and enzymatic catalysis. In 23 chapters by noted experts, the volume demonstrates varied approaches using model systems and their successes in understanding aspects of heterogeneous catalysis, both metal- and metal oxide-based catalysis in extended single crystal and nanostructured catalytic materials. To truly appreciate the astounding advances of modern heterogeneous catalysis, let us first consider the subject from a historical...
This book is an excellent compilation of cutting-edge research in heterogeneous catalysis and related disciplines - surface science, organometallic ca...
|
cena:
603,81 |
![]() |
Recognition Receptors in Biosensors
ISBN: 9781441909183 / Angielski / Twarda / 863 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Recognition receptors play a key role in the successful implementation of chemical and biosensors. Molecular recognition refers to non-covalent speci?c binding between molecules, one of which is typically a macromolecule or a molecular assembly, and the other is the target molecule (ligand or analyte). Biomolecular recognition is typically driven by many weak interactions such as hydrogen bo- ing, metal coordination, hydrophobic forces, van der Waals forces, pi-pi interactions and electrostatic interaction (due to permanent charges, dipoles, and quadrupoles) the polarization of charge...
Recognition receptors play a key role in the successful implementation of chemical and biosensors. Molecular recognition refers to non-covalent speci?...
|
cena:
805,10 |
![]() |
Aromaticity and Metal Clusters
ISBN: 9781439813348 / Angielski / Twarda / 466 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Metal clusters, an intermediate state between molecules and the extended solid, show peculiar bonding and reactivity patterns. Their significance is critical to many areas, including air pollution, interstellar matter, clay minerals, photography, catalysis, quantum dots, and virus crystals. In Aromaticity and Metal Clusters, dozens of international experts explore not only the basic aspects of aromaticity, but also the structures, properties, reactivity, stability, and other consequences of the aromaticity of a variety of metal clusters. Although the concept... Metal clusters, an intermediate state between molecules and the extended solid, show peculiar bonding and reactivity patterns. Their significance i... |
cena:
930,57 |
![]() |
Melt Extrusion: Materials, Technology and Drug Product Design
ISBN: 9781461484318 / Angielski / Twarda / 474 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. This volume provides readers with the basic principles and fundamentals of extrusion technology and a detailed description of the practical applications of a variety of extrusion processes, including various pharma grade extruders. In addition, the downstream production of films, pellets and tablets, for example, for oral and other delivery routes, are presented and discussed utilizing melt extrusion. This book is the first of its kind that discusses extensively the well-developed science of extrusion technology as applied to pharmaceutical drug product development and manufacturing. By...
This volume provides readers with the basic principles and fundamentals of extrusion technology and a detailed description of the practical applicatio...
|
cena:
603,81 |
![]() |
Naturally Occurring Glycosides
ISBN: 9780471986027 / Angielski / Twarda / 460 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Glycosides are sugar derivatives in which the hydroxyl (-OH) group attached to carbon 1 is substituted by an alcoholic, phenolic or other groups which are used medicinally for their stimulant effects on the heart. There are a number of glycocides which occur in nature, mainly in plants. These compounds have found importance in therapeutic, nutritional and clinical use because they possess a variety of biological activities.
Glycosides are sugar derivatives in which the hydroxyl (-OH) group attached to carbon 1 is substituted by an alcoholic, phenolic or other groups which...
|
cena:
2908,71 |
![]() |
Ionic Liquids: Physicochemical Properties
ISBN: 9780444534279 / Angielski / Twarda / 478 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. This comprehensive database on physical properties of pure ionic liquids (ILs) contains data collected from 269 peer-reviewed papers in the period from 1982 to June 2008. There are more than 9,400 data points on the 29 kinds of physicochemical properties for 1886 available ionic liquids, from which 807 kinds of cations and 185 kinds of anions were extracted. This book includes nearly all known pure ILs and their known physicochemical properties through June 2008. In addition, the authors incorporate the main applications of individual ILs and a large number of references.
This comprehensive database on physical properties of pure ionic liquids (ILs) contains data collected from 269 peer-reviewed papers in the period fro...
|
cena:
930,57 |
![]() |
Extraction Techniques in Analytical Sciences
ISBN: 9780470772850 / Angielski / Twarda / 308 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. This book covers one of the most important areas in analytical sciences, i.e. that of extraction techniques for organic compounds in environmental and related matrices, e.g. food. This text discusses all of the key stages for analysing a sample for organic compounds from the initial sampling protocols through to the range of different extraction techniques used for solid, liquid and air samples and finally through to the final chromatographic analysis. The text provides detailed information on specific extraction techniques to prepare samples for organic compound analysis.
The topics... This book covers one of the most important areas in analytical sciences, i.e. that of extraction techniques for organic compounds in environmental and...
|
cena:
729,51 |
![]() |
Aspects of African Biodiversity: Proceedings of the Pan Africa Chemistry Network Biodiversity Conference
ISBN: 9781847559487 / Angielski / Twarda / 204 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. This book is the proceedings of the Pan Africa Chemistry Network Biodiversity Conference which was held in September 2008. A key aim of the RSC/Syngenta Pan Africa Chemistry Network (PACN) is to connect African scientists through a cycle of conferences and workshops and this conference held at the University of Nairobi was the first of these. It brought together 26 speakers from nine African countries - Kenya, Ethiopia, Tanzania, South Africa, Nigeria, Botswana, Uganda, Zimbabwe and Sudan - plus the UK and Brazil. The lectures covered topics such as making the best use of the diversity of...
This book is the proceedings of the Pan Africa Chemistry Network Biodiversity Conference which was held in September 2008. A key aim of the RSC/Syngen...
|
cena:
489,53 |
![]() |
Drug Design: Cutting Edge Approaches
ISBN: 9780854048168 / Angielski / Twarda / 202 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Pharmaceutical research draws on increasingly complex techniques to solve the challenges of drug design. Bringing together a number of the latest informatics techniques, this book looks at modelling and bioinformatic strategies; structural genomics and X-ray crystallography; virtual screening; lead optimisation; ADME profiling and vaccine design. A number of relevant case studies, focussing on techniques that have demonstrated their use, will concentrate on G-protein coupled receptors as potential disease targets. Providing details of state-of-the-art research, Drug Design: Cutting Edge...
Pharmaceutical research draws on increasingly complex techniques to solve the challenges of drug design. Bringing together a number of the latest info...
|
cena:
416,30 |
![]() |
Clean Synthesis Using Porous Inorganic Solid Catalysts and Supported Reagents
ISBN: 9780854045266 / Angielski / Twarda / 118 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Waste minimisation has a number of aims which include enhancing the intrinsic selectivity of any given process, providing a means of recovering reagents in a form which allows easy regeneration and the replacement of stoichiometric processes with catalytic ones. Solids, as catalysts or as supports for other reagents, offer potential for benefit in all these areas. This monograph provides an overview of the properties of the more useful solid catalysts and supported reagents, and highlights their most valuable applications in the preparation of organic chemicals in liquid phase reactions....
Waste minimisation has a number of aims which include enhancing the intrinsic selectivity of any given process, providing a means of recovering reagen...
|
cena:
318,35 |
![]() |
Chemistry of Protein and Nucleic Acid Cross-Linking and Conjugation
ISBN: 9780849374913 / Angielski / Twarda / 622 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Since the publication of the first edition of Chemistry of Protein Conjugation and Cross-Linking in 1991, new cross-linking reagents, notably multifunctional cross-linkers, have been developed and synthesized. The completion of the human genome project has opened a new area for studying nucleic acid and protein interactions using nucleic acid cross-linking reagents, and advances have also been made in the area of biosensors and microarray biochips for the detection and analysis of genes, proteins, and carbohydrates. In addition, developments in physical techniques with... Since the publication of the first edition of Chemistry of Protein Conjugation and Cross-Linking in 1991, new cross-linking reagen... |
cena:
1346,88 |
![]() |
Transition Metal Sulphides: Chemistry and Catalysis
ISBN: 9780792352556 / Angielski / Twarda / 356 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Hydrotreating catalysis with transition metal sulphides is one of the most important areas of industrial heterogeneous catalysis. The present book deals with the chemical and catalytic aspects of transition metal sulphides, focusing on their use in hydrotreating catalysis. The book s 12 chapters present reviews of solid-state, coordination and organometallic chemistry, surface science and spectroscopic studies, quantum chemical calculations, catalytic studies with model and real catalysts, as well as refinery processes. A presentation of state-of-the-art background to pertinent work in the...
Hydrotreating catalysis with transition metal sulphides is one of the most important areas of industrial heterogeneous catalysis. The present book dea...
|
cena:
805,10 |
![]() |
Methods for Affinity-Based Separations of Enzymes and Proteins
ISBN: 9783764363062 / Angielski / Twarda / 225 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. One major concern of biotechnology is either using enzymes or producing them. Enzyme/protein production is therefore an important starting point for biotechnology. Bioseparation or Downstream Processing constitutes about 40-90% of the total production cost. Driven by economics, highly selective technologies applicable to large-scale processing have emerged during the last decade. These technologies are slowly diffusing to enzymologists who are working on a smaller scale, looking for fast and efficient purification protocols. The affinity-based techniques (including precipitation, two-phase... One major concern of biotechnology is either using enzymes or producing them. Enzyme/protein production is therefore an important starting point fo... |
cena:
201,24 |
![]() |
Methods in Non-Aqueous Enzymology
ISBN: 9783764358037 / Angielski / Twarda / 218 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Extending the range of enzymatic catalysis by using non-aqueous media considerably enlarges the range of enzyme applications and became a po werful approach in biochemistry and biotechnology. This book discusses several specific applications in nearly anhydrous media, aqueous-orga nic co-solvent mixtures and reverse micelles, including use of enzymes in fat and oil processing, peptide synthesis, sugar transformations a nd preparation of chiral compounds. A particularly promising approach of using reverse micelles for modifying proteins is also described.
Extending the range of enzymatic catalysis by using non-aqueous media considerably enlarges the range of enzyme applications and became a po werful ap...
|
cena:
603,81 |
![]() |
Hydrogen Bond Research
ISBN: 9783211833964 / Angielski / Twarda / 118 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Features seven review articles and original papers that provide an overview of the research work done in hydrogen bond research at Austrian universities. This work covers topics such as: understanding hydrogen bonding in biopolymers; NMR techniques for studying hydrogen bonding in aqueous solutions; and more.
Features seven review articles and original papers that provide an overview of the research work done in hydrogen bond research at Austrian universiti...
|
cena:
402,53 |
![]() |
Cosmetic and Pharmaceutical Applications of Polymers
ISBN: 9780306440885 / Angielski / Twarda / 414 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Polymers continue to show almost amazing versatility. We have always known that polymers could be used for trinkets, toys and dishes. Now, however, we are no longer surprised to encounter these adaptable mate rials in almost every place we look. We find them in our cars, tools, electronic devices, building materials, etc. The use of polymeric mate rials in medicine is also well documented in previous books by one of the Editors (Gebelein) and by others. Likewise, the use of polymeric mate rials in pharmaceutical applications, especially in controlled release systems, is also well established....
Polymers continue to show almost amazing versatility. We have always known that polymers could be used for trinkets, toys and dishes. Now, however, we...
|
cena:
805,10 |
![]() |
Current Topics in Flavours and Fragrances: Towards a New Millennium of Discovery
ISBN: 9780751404906 / Angielski / Twarda / 235 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. This book is designed to give the reader up to date infonnation on some of the more exciting developments that have taken place at the leading edge of fragrance and flavour research. Chapter one gives the reader a rnpid excursion through the chronological landmarks of fragrance and flavour materials and sets the scene for the remaining nine chapters which cover topics that are at the forefront of modem research. Chapter two looks at the total synthesis of synthetically interesting perfumery naturnl materials. This chapter aims to highlight the creative and elegant chemistry that has been...
This book is designed to give the reader up to date infonnation on some of the more exciting developments that have taken place at the leading edge of...
|
cena:
402,53 |
![]() |
Advances in Clinical Chemistry: Volume 52
ISBN: 9780123809483 / Angielski / Twarda / 192 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Volume 47 in the internationally acclaimed Advances in Clinical Chemistry contains chapters submitted from leading experts from academia and clinical laboratory science. Authors are from a diverse field of clinical chemistry disciplines and diagnostics, ranging from basic biochemical exploration to cutting-edge microarray technology.
Volume 47 in the internationally acclaimed Advances in Clinical Chemistry contains chapters submitted from leading experts from academia and... |
cena:
744,45 |