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Medicinal Organometallic Chemistry
ISBN: 9783642131844 / Angielski / Twarda / 294 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. This book includes: Gerard Jaouen, Nils Metzler-Nolte: Introduction; Stephane GIBAUD and Gerard JAOUEN: Arsenic - based drugs: from Fowler's solution to modern anticancer chemotherapy; Ana M. Pizarro, Abraha Habtemariam and Peter J. Sadler: Activation Mechanisms for Organometallic Anticancer Complexes; Angela Casini, Christian G. Hartinger, Alexey A. Nazarov, Paul J. Dyson: Organometallic antitumour agents with alternative modes of action; Elizabeth A. Hillard, Anne Vessieres, Gerard Jaouen: Ferrocene functionalized endocrine modulators for the treatment of cancer; and, Megan Hogan and...
This book includes: Gerard Jaouen, Nils Metzler-Nolte: Introduction; Stephane GIBAUD and Gerard JAOUEN: Arsenic - based drugs: from Fowler's solution ...
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cena:
1204,83 |
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Laboratory Experiments Using Microwave Heating
ISBN: 9781439856093 / Angielski / Miękka / 232 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Allowing many chemical reactions to be completed within minutes, microwave heating has revolutionized preparative chemistry. As a result, this technology has been widely adopted in both academic and industrial laboratories. Integrating microwave-assisted chemistry into undergraduate laboratory courses enables students to perform a broader range of reactions in the allotted lab period. As a result, they can be introduced to chemistry that would otherwise have been inaccessible due to time constraints (for example, the need for an overnight reflux). Allowing many chemical reactions to be completed within minutes, microwave heating has revolutionized preparative chemistry. As a result, this tech... |
cena:
436,25 |
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Biomedical Aspects of Histamine: Current Perspectives
ISBN: 9789048193486 / Angielski / Twarda / 441 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Since its identification by Sir Henry Dale a century ago, histamine has become one of the most important multifunctional biogenic amines in the field of biomedicine. The pharmacologic effects of histamine are mediated through four types of membrane histamine receptors; H1R, H2R, H3R and H4R, which are all heptahelical G-protein-coupled receptors. It has been known to play the broadest spectrum of activities in various physiological and pathological conditions including cell proliferation, differentiation, hematopoiesis, embryonic development, regeneration, wound healing, aminergic...
Since its identification by Sir Henry Dale a century ago, histamine has become one of the most important multifunctional biogenic amines in the field ...
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cena:
803,21 |
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Development of New MDR-Tuberculosis Drugs
ISBN: 9781616682330 / Angielski / Miękka / 98 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. The emergence of resistance to anti-tuberculosis drugs, particularly of MDR-TB and newly XDR-TB, has become a major public health problem. The current treatment regiment has several disadvantages, i.e. long treatment period (DOTS takes minimum 6 months) during which tubercle bacilli mutant become resistant to one or more drugs; side effects of the used drugs; co-infection of HIV/AIDS. The emergence of MDR-TB has made many currently available anti-TB drugs ineffective. Sleeping latent forms of mutant bacilli resistant against common anti-TB drugs pose the risk of epidemic for the new...
The emergence of resistance to anti-tuberculosis drugs, particularly of MDR-TB and newly XDR-TB, has become a major public health problem. The current...
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cena:
316,33 |
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Computational Chemistry: A Practical Guide for Applying Techniques to Real World Problems
ISBN: 9780470880081 / Angielski / Miękka / 408 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. A practical, easily accessible guide for bench-top chemists, this book focuses on accurately applying computational chemistry techniques to everyday chemistry problems.
A practical, easily accessible guide for bench-top chemists, this book focuses on accurately applying computational chemistry techniques to everyday c...
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cena:
461,82 |
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Copper-Catalyzed Multi-Component Reactions: Synthesis of Nitrogen-Containing Polycyclic Compounds
ISBN: 9783642154720 / Angielski / Twarda / 104 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. As the concept of Green Chemistry becomes ever more important, the findings presented in this book may provide efficient and atom-economical approaches to the diversity-oriented synthesis of bioactive compounds containing a complex structure. As the concept of Green Chemistry becomes ever more important, the findings presented in this book may provide efficient and atom-economical approa... |
cena:
200,77 |
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Ruthenium Catalysts and Fine Chemistry
ISBN: 9783642058158 / Angielski / Miękka / 337 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Molecular ruthenium catalysts, during the last decade, have provided new indispensable synthetic methods that cannot be promoted by other catalysts, and they now constitute an emerging field for the selective preparation of fine chemicals. The major reaction types for carbon-carbon and carbon-heteroatom bond formation, most of them with atom economy, are comprehensively discussed by leading experts. The authors highlight the most important discoveries in ruthenium catalysis and propose activation processes, some of them being still controversial. They illustrate the innovation and... Molecular ruthenium catalysts, during the last decade, have provided new indispensable synthetic methods that cannot be promoted by other catalysts... |
cena:
879,56 |
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Metal Carbenes in Organic Synthesis
ISBN: 9783642060038 / Angielski / Miękka / 378 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Metal carbene complexes have made their way from organometallic curiosities to valuable reagents and catalysts. They offer novel synthetic opportunities in carbon carbon bond formation based on either carbene-centered reactions or on metal-templated processes which makes them indispensable in modern synthetic methodology. The most prominent metal carbenes are now either commercially available or easy to synthesize and handle by modern laboratory techniques. This volume organized in eight chapters written by the leading scientists in the field illustrates the theoretical background,... Metal carbene complexes have made their way from organometallic curiosities to valuable reagents and catalysts. They offer novel synthetic opportun... |
cena:
1204,83 |
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Regenerative Medicine I: Theories, Models and Methods
ISBN: 9783642061691 / Angielski / Miękka / 196 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Organ regeneration, once unknown in adult mammals, is at the threshold of maturity as a clinical method for restoration of organ function in humans. Several laboratories around the world are engaged in the development of new tools such as stem cells and biologically active scaffolds. Others are taking fresh looks at well-known clinical problems of replacement of a large variety of organs: Bone, skin, the spinal cord, peripheral nerves, articular cartilage, the conjunctiva, heart valves and urologic organs. Still other investigators are working out the mechanistic pathways of regeneration... Organ regeneration, once unknown in adult mammals, is at the threshold of maturity as a clinical method for restoration of organ function in humans... |
cena:
1124,51 |
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Palladium in Organic Synthesis
ISBN: 9783642063084 / Angielski / Miękka / 334 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Palladium is a remarkable metal. In particular, organopalladium chemistry has made remarkable progress over the last 30 years. That progress is still continuing, without any end in sight. This book presents a number of accounts and reviews on the novel Pd-catalyzed reactions discovered mainly in the last five years. The book covers Pd-catalyzed reactions that are new entirely different from the more standard ones. Topics such as new reactions involving ss-carbon elimination and formation of palladacycles as key reactions, cross-coupling of unactivated alkyl electrophiles with... Palladium is a remarkable metal. In particular, organopalladium chemistry has made remarkable progress over the last 30 years. That progress is sti... |
cena:
1204,83 |
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Bioorganometallic Chemistry
ISBN: 9783642069581 / Angielski / Miękka / 222 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Bioorganometallic Chemistry has become a mature area of science and is comprehensively covered by leading experts in this book. Naturally occuring bioorganometallic complexes, such as vitamin B12 and recently discovered iron and nickel hydrogenases, including a possible role of the latter in the geochemical theory of the origin of life, are considered. The possible formation of carbene complexes of cytochrome P450 enzymes in various metabolisms of xenobiotics is also discussed. The bioorganometallic chemistry is considered to provide not only organometallic receptors such as...
Bioorganometallic Chemistry has become a mature area of science and is comprehensively covered by leading experts in this book. Naturally occuring bio...
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cena:
803,21 |
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Peptide-Based Drug Design
ISBN: 9781617378690 / Angielski / Miękka / 303 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Due to their high specificity and low toxicity profile, peptides have once again become central to the development of new drugs. In Peptide-Based Drug Design: Methods and Protocols, expert researchers provide a handbook which offers a selection of research and production tools suitable for transforming a promising protein fragment or stand-alone native peptide into a pharmaceutically acceptable composition. The volume delves into contemporary, cutting-edge subjects such as hit isolation and target validation, computer-aided design, sequence modifications to satisfy pharmacologists, in vivo... Due to their high specificity and low toxicity profile, peptides have once again become central to the development of new drugs. In Peptide-Based D... |
cena:
602,40 |
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High Content Screening
ISBN: 9781617377464 / Angielski / Miękka / 464 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. High content screening (HCS) was developed by Cellomics Inc. in the mid-1990s to address the need for a platform that could be used in the discovery-driven research and development required to understand the functions of genes and gene products at the level of the cell. High Content Screening: A Powerful Approach to Systems Cell Biology and Drug Discovery discusses its use as a high throughput platform to understand the functions of genes, RNA, proteins, and other cellular constituents at the level of the living cell.
High Content Screening is assembled to assist both existing users of... High content screening (HCS) was developed by Cellomics Inc. in the mid-1990s to address the need for a platform that could be used in the discovery-d...
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cena:
602,40 |
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Inclusion Polymers
ISBN: 9783642101793 / Angielski / Miękka / 240 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. This book contains short and concise reports on physics and chemistry of polymers, each written by the world renowned experts. The book has the highest Impact Factor of all journals ranked by ISI within Polymer Science. This book contains short and concise reports on physics and chemistry of polymers, each written by the world renowned experts. The book has the hig... |
cena:
1204,83 |
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Phosphorous Heterocycles I
ISBN: 9783642101441 / Angielski / Miękka / 314 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. The next article includes the description of the rich chemistry of phosphinines, including azaphosphinines. The sixth article deals with synthetic approaches to different types of 1- heterophosphacyclanes, including four-, five-, and six-membered P-heterocycles. The next two articles cover the chemistry of phosphorus containing mac- cycles. The phosphorus containing calixarenes have attracted much attention in recent years due to their various functions such as metal cations binding, catalysis, molecular recogination, and bioactivity. Likewise, other phosphorus-containing macrocycles,...
The next article includes the description of the rich chemistry of phosphinines, including azaphosphinines. The sixth article deals with synthetic app...
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cena:
1204,83 |
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Bioactive Heterocycles IV
ISBN: 9783642092459 / Angielski / Miękka / 317 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. This volume contains nine more contributions from expert researchers of the ?eld, providing readers with in depth and current research results regarding therespective topics. In the ?rst chapter, Flemming et al. review the chemistry, biosynthesis, metabolism and biological activities of tetrahydrocannabinol and its deri- tives. Hansch and Verma contribute to the quantitative structure-activity re- tionship (QSAR) analysis of heterocyclic topoisomerase I and II inhibitors. These inhibitors, knowntoinhibit either enzyme, actasantitumoragentsand are currently used in chemotherapy and in...
This volume contains nine more contributions from expert researchers of the ?eld, providing readers with in depth and current research results regardi...
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cena:
803,21 |
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Bioactive Heterocycles III
ISBN: 9783642092442 / Angielski / Miękka / 287 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. "Bioactive Heterocycles III" provides readers with a comprehensive overview of the most recent breakthroughs in the ?eld of heterocycles. This volume contains 8 chapters written by experts in their respective ?elds from all over the world. The chapters summarize years of extensive research in each area, andprovideinsightinthenewthemesofnaturalproductresearch.Manyofthe contributors illustrate their laboratory experiences. It's obvious that readers will gain exciting and essential information fromthe volume. In the ?rst chapter, Kayser et al. describe the chemistry, biosynthesis and biological...
"Bioactive Heterocycles III" provides readers with a comprehensive overview of the most recent breakthroughs in the ?eld of heterocycles. This volume ...
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cena:
803,21 |
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Novel Optical Resolution Technologies
ISBN: 9783642079696 / Angielski / Miękka / 313 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. After theend ofthe 20th century, the science ofcrystallizationreached a truly exciting stage where new opportunities emerged in both theory and expe- ment. Variousphysical methodsare capableofresolvingthesurface as wellas theinsidestructureofcrystalsattheatomiclevelwhilenewhigh-performance computingresourcesaffordthecapabilityofmodelingthecomplexlarge-scale alignmentsnecessarytosimulatecrystallizationinrealsystems.Asaresult, the science of crystallization has shifted gradually fromstatic to dynamic science and considerable progress now underlies the complex but beautiful cryst- lization...
After theend ofthe 20th century, the science ofcrystallizationreached a truly exciting stage where new opportunities emerged in both theory and expe- ...
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cena:
1204,83 |
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Glycopeptides and Glycoproteins: Synthesis, Structure, and Application
ISBN: 9783642071836 / Angielski / Miękka / 265 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. In the last 50 years molecular biology was dominated by the exploration of proteins and nucleic acids. Beside their role in energy metabolism, oligos- charides, which represent thethirdclass ofbiomacromolecules, have received less attention. Today it is well established that oligosaccharides are involved in many important biologicalregulation and recognition processes fromp- tein folding to cell cell communication. Glycosylation of proteins is the most complexformofco-andposttranslationalmodi?cation. Thedeterminationof structure-function relationships, however, remains dif?cult due to the...
In the last 50 years molecular biology was dominated by the exploration of proteins and nucleic acids. Beside their role in energy metabolism, oligos-...
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cena:
803,21 |
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Bioactive Molecules and Medicinal Plants
ISBN: 9783642094057 / Angielski / Miękka / 379 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Use of medicinal plants is as old as human civilization and continuous efforts are being made to improve medicinal plants or produce their products in high amounts through various technologies. About 200,000 natural products of plant origin are known and many more are being identifed from higher plants and microorganisms. Some plant-based drugs have been used for centuries and there is no alternative medicine for many drugs, such as cardiac glycosides. However, natural products research was sidelined to pave the way for com- natorial chemistry, which was expected to produce large numbers of...
Use of medicinal plants is as old as human civilization and continuous efforts are being made to improve medicinal plants or produce their products in...
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cena:
803,21 |