Kategoria BISAC: Science >> Chemistry - Clinical

Hydroxyketones: Preparation and Physical Properties (c2500pp in 4 volumes)

SUMMARY

VOLUME 1- Hydroxybenzophenones are useful synthetic intermediates in chemical industry, for example in pharmaceuticals, dyes, fragrances, agrochemicals, explosives and plastics. In this handbook, the diverse ways of obtaining over 1900 hydroxybenzophenones are described, and their physico-chemical properties and spectroscopic data references are indicated. Hence, ketones are classified methodically. They are thus easily accessible from three tables: the molecular formula index, the chemical...

Drug research has been greatly transformed by the "omics revolution" and advances in computational tools, combinatorial chemistry, and high throughput screening techniques (HTS). These implements have advanced the ability to identify target molecules that serve as points of attack for future medicines, the design and synthesis of potential lead compounds, and further characterization, screening, and assays for therapeutic efficacy and toxicity. In Ligand-Macromolecular Interactions in Drug Discovery: Methods and Protocols, experts in the field highlight the main principles and...

Volume 47 in the internationally acclaimed Advances in Clinical Chemistry contains chapters submitted from leading experts from academia and clinical laboratory science. Authors are from a diverse field of clinical chemistry disciplines and diagnostics, ranging from basic biochemical exploration to cutting-edge microarray technology.

• Leading experts from academia and clinical laboratory science
• Volume emphasizes novel laboratory advances with application to clinical laboratory diagnostics and practical basic science studies

"Practical Aspects of Computational Chemistry" presents contributions on a range of aspects of Computational Chemistry applied to a variety of research fields. The chapters focus on recent theoretical developments which have been used to investigate structures and properties of large systems with minimal computational resources. Studies include those in the gas phase, various solvents, various aspects of computational multiscale modeling, Monte Carlo simulations, chirality, the multiple minima problem for protein folding, the nature of binding in different species and dihydrogen bonds,...

The series contains updated and comprehensive compendiums of molecular modelling software that list hundreds of programs, services, suppliers and other information that every chemist will find useful.

As mass spectrometric methods now offer a level of specificity and sensitivity unrealized by spectrophotometric- and immunoassay-based methods, mass spectrometry has entered the clinical laboratory where it is being used for a wide range of applications. In Clinical Applications of Mass Spectrometry: Methods and Protocols, expert researchers provide detailed step-by-step procedures for the analysis of number of analytes of clinical importance. This versatile and expansive volume covers mass spectrometry methods for analytes including a variety of drugs, hormones, and metabolic...

Contents: Yves Canac and Remi Chauvin: Neutral eta1-carbon ligands: beyond carbon monoxide; Esteban P. Urriolabeitia: Ylide Ligands; Wolfgang Petz and Gernot Frenking: Carbodiphosphoranes and related ligands; Mareike C. Jahnke and F. Ekkehardt Hahn: Chemistry of N-Heterocyclic Carbene Ligands; Tsuyoshi Kato, Eddy Maerten, Antoine Baceiredo: Non-NHCs stable singlet carbene ligands; Victorio Cadierno, Sergio E. Garcia-Garrido: All-Carbon-Substituted Allenylidene and Related Cumulenylidene Ligands; Victorio Cadierno, Sergio E. Garcia-Garrido: Heteroatom-Conjugated Allenylidene and Related...

• Covers findings related to cardiovascular, inflammation, and pulmonary diseases
• Examines issues in oncology, from mTor inhibitors to drug targets
• Incorporates up-to-date information on drug design and discovery, including delivery to market

Molecular and Cellular Enzymology addresses not only experienced enzymologists but also students, teachers and academic and industrial researchers who are confronted with enzymological problems during their fundamental or applied research. In this field is an urgent need for training in order to meet the requirements of both research and industrial endeavours. This book consists of several levels. Practical aspects and elementary explanations are given for the benefit of non-specialists' and students' understanding. In order to facilitate the task of students, two typographies have been...

Within recent years pharmaceuticals have come into focus as contaminants of the environment (see for example Kummerer, K. editor: Pharmaceuticals in the Environment). At the same time the issue of sustainable chemistry gained momentum. Bringing both together would result in sustainable pharmacy. Sustainable pharmacy is a totally new issue and approach. It addresses environmental, economical and social aspects of pharmacy. In the present stage the focus will be on environmental issues along the whole lifecycle of a pharmaceutical entity. That is dealing with resources and energy input but...

Of the thousands of biomarkers that are currently being discovered, relatively few are being validated for further applications, and the potential of a biomarker can be quite difficult to evaluate. To aid in this imperative research, Dr. Kewal K. Jain's Handbook of Biomarkers thoroughly describes many different types of biomarkers and their discovery using various "-omics" technologies, such as proteomics and metabolomics, along with the background information needed for the evaluation of biomarkers as well as the essential procedures for their validation and use in clinical...

Advances in Clinical Chemistry, Volume 75, the latest installment in this internationally acclaimed series, contains chapters authored by world-renowned clinical laboratory scientists, physicians, and research scientists. This serial discusses the latest and most up-to-date technologies related to the field of clinical chemistry and is the benchmark for novel analytical approaches in the clinical laboratory.

• Contains the expertise of international contributors
• Provides the latest cutting-edge technologies in the field of clinical chemistry
• Authored...