Metal Carbenes in Organic Synthesis

ISBN-13: 9783642060038 / Angielski / Miękka / 2010 / 378 str.

Karl Heinz Dotz

Opis

Metal carbene complexes have made their way from organometallic curiosities to valuable reagents and catalysts. They offer novel synthetic opportunities in carbon carbon bond formation based on either carbene-centered reactions or on metal-templated processes which makes them indispensable in modern synthetic methodology. The most prominent metal carbenes are now either commercially available or easy to synthesize and handle by modern laboratory techniques. This volume organized in eight chapters written by the leading scientists in the field illustrates the theoretical background, non-classical nucleophilic and cycloaddition patterns, chromium-templated benzannulation and photo-induced reactions, rhodium-catalyzed carbene transfer as well as the principles and applications of olefin metathesis which coined the progress in synthetic methodology over the past decade. Designed for researchers in academia and industry as well as graduate students it presents the state-of-the-art potential of carbene complexes in modern organic synthesis.

Recenzje

From the reviews:

"As stated by the editor, 'the aim of this book is to convince the reader that metal carbene complexes have made their way from ... for application in synthesis and catalysis.' By this measure, this book has succeeded. ... this is a valuable book for those who are interested in research in the area of carbene complexes in organic synthesis. ... The contributions are up-to-date, and they have references ... . The book is highly recommended ... ." (William D. Wulff, Journal of the American Chemical Society, Vol. 127 (45), 2005)

Spis treści

T. Strassner: Electronic Structure and Reactivity of Metal Carbenes.- Y.-T. Wu, A. de Meijere: The Multifaceted Chemistry of Variously Substituted a,b-Unsaturated Fischer Metalcarbenes.- J. Barluenga, F. Rodríguez, F.J. Fañanás and J. Flórez: Cycloaddition Reactions of Group 6 Fischer Carbene Complexes.- A. Minatti, K.H. Dötz: Chromium-Templated Benzannulation Reactions.- L.S. Hegedus: Photoinduced Reactions of Metal Carbenes in Organic Synthesis.- M.P. Doyle: Metal Carbene Reactions from Dirhodium(II) Catalysts.- B. Schmidt, J. Hermanns: Olefin Metathesis Directed to Organic Synthesis: Principles and Applications.- J. Mulzer, E. Öhler: Diene, Enyne and Diyne Metathesis in Natural Product Synthesis