Kategoria BISAC: Science >> Life Sciences - Biology

Providing an important and timely overview of research on the exciting area of entrepreneurship in biotechnology, The Handbook of Bioentrepreneurship examines one of the most promising industries of the 21st century. While genetically engineered food and biopharmaceuticals have made biotechnology part of our everyday life, starting a bioventure is among the most complex and risky entrepreneurial tasks given long development cycles, high technological and market uncertainty, and high capital intensity. Providing unparalleled in-depth and detailed analysis, this...

Elwyn Simons has held professional appointments at Yale University (1960-1977), Duke University (1977-present), and was the Director of the Duke Primate Center (1977-1991) and Scientific Director (1991-2001). He has authored nearly 300 scientific publications and is the holder of many high honors. He is a member of the United States National Academy of Sciences, the American Philosophical Society, as well as many other professional associations. He was elected a "Knight of the National Order" by the government of Madagascar and has been the recipient of many awards including the...

Lysosomes are membrane-surrounded organelles which are present in all animal cells. The importance of this organelle is underlined by an increasing number of human diseases, which are associated with an impaired function of the lysosomal compartment.

This book summarizes the current state-of-the art knowledge about this unique organelle. It addresses the biogenesis of this compartment, the transport of lysosomal proteins, the role of the lysosomal membrane in lysosomal stability and transport, the function of lysosomal proteases and hydrolases, lysosomal storage disorders, and new...

Novel drugs are being developed which interact with the programmed cell death (apoptotic) machinery in cancer cells, thereby causing these cells to commit suicide and to be removed from the body. Research is also directed to investigate why the cancer cells sometimes lose the ability to undergo apoptosis after a certain period of time and methods are being developed to reactivate this cell death process. This book is intended for workers in the field and clinicians as a useful guide of the state of affairs in this exciting field which may offer more effective possibilities for treatment of...

PGPR have gained world wide importance and acceptance for agricultural benefits. These microorganisms are the potential tools for sustainable agriculture and the trend for the future. Scientific researches involve multidisciplinary approaches to understand adaptation of PGPR to the rhizosphere, mechanisms of root colonization, effects on plant physiology and growth, biofertilization, induced systemic resistance, biocontrol of plant pathogens, production of determinants etc. Biodiversity of PGPR and mechanisms of action for the different groups: diazotrophs, bacilli, pseudomonads, and...

Forests provide goods and services essential to human societies and the natural environment, but they are disappearing faster today than ever before. What should forestry do in the information era? How can we use computer technologies to better manage forests in a sustainable manner? Computer Applications in Sustainable Forest Management provides critical information needed for forestry professionals to address such questions.

Computer Applications in Sustainable Forest Management presents state-of-the-art computer applications in a variety of...

The ability of striated muscle tissue to adapt to changes in activity or in working conditions is extremely high. In some ways it is comparable to the ability of the brain to learn. The interest in muscle adaptation is increasing in relation to the idea that physical fitness helps in the prevention of disease, may counteract the loss of physical performance and generally improves wellbeing. Plasticity is the word used since the late 1970 s to indicate collectively all the processes and mechanisms which form the background of muscle adaptation. This book aims to provide a systematic...

Kary Mullis was awarded a Nobel Prize for inventing the PCR technique more than a decade ago in 1993. Since its "discovery," multiple adaptations and variations of the standard PCR technique have been described. This publication aims to provide the reader with a guide to the standard PCR technique and its many available variants, with particular emphasis being placed on the role of these PCR techniques in the clinical diagnostic laboratory (the central theme of this book).

The processes of tumor metastasis, apoptosis and anti-tumor immune response are among the most complex yet rapidly advancing fields in the area of cancer research. This monogaph presents a comprehensive coverage of the recent advances in the various key concepts in these fundamental aspects of human cancer. It would be of particular interest to members of the cancer research community, especially those who are actively involved in the study of basic and translational aspects of human cancer. Specifically, this volume includes authentic subject reviews by leading experts on the following...

Neuropsychiatric disorders such as schizophrenia, mood disorders, Alzheimer s disease, epilepsy, alcoholism, substance abuse and others are one of the most debilitating illnesses worldwide characterizing by the complexity of the causes, and lacking the laboratory tests that may promote diagnostic and prognostic procedures. Recent advances in neuroscience, genomic, genetic, proteomic and metabolomic knowledge and technologies have opened the way to searching biomarkers and endophenotypes, which may offer powerful and exciting opportunity to understand the etiology and the underlying...

As individuals age, their ability to respond to and clear pathogens and to control unwanted immune reactions declines, leading to a greater incidence of certain infectious diseases, autoimmunity and general immune dysfunctions. Most remarkably, the efficacy of vaccines is frequently decreased in elderly persons. Therefore, age-associated dysfunctions of the humoral and cellular immune responses have a strong clinical impact. Improving our understanding of the aged immune system is crucial in developing effective prevention and treatment programs that will facilitate healthy aging and...

Robert Rosen was not only a biologist, he was also a brilliant mathematician whose extraordinary contributions to theoretical biology were tremendous. Founding, with this book, the area of Anticipatory Systems Theory is a remarkable outcome of his work in theoretical biology.

This second edition of his book Anticipatory Systems, has been carefully revised and edited, and includes an Introduction by Judith Rosen. It has also been expanded with a set of Prolegomena by Dr. Mihai Nadin, who offers an historical survey of this fast growing field since the original work was...

Mitochondria and chloroplasts are eukaryotic organelles that evolved from bacterial ancestors and harbor their own genomes. The gene products of these genomes work in concert with those of the nuclear genome to ensure proper organelle metabolism and biogenesis.

This book explores the forces that have shaped the evolution of organelle genomes and the expression of the genes encoded by them. Some striking examples of trends in organelle evolution explored here are the reduction in genome size and gene coding content observed in most lineages, the complete loss of organelle DNA in...

There is a veritable gold rush mentality in the life science world as scientists, entrepreneurs and multinationals are staking claims to the code of life embodied in the world s current stock of plants, animals, microbes and human populations. In response, the communities that see themselves as the custodians of both that traditional knowledge and specific genetic resources have demanded greater recognition of their role in creating and conserving this resource, access to any resulting improvements and a share of the benefits arising from their patrimony. This has precipitated a widespread...