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Integrins and Ion Channels: Molecular Complexes and Signaling
ISBN: 9781441960658 / Angielski / Twarda / 124 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Interdisciplinarity is more often invoked than practised. This is hardly surprising, considering the daunting vastness of modern biology. To reach a satisfactory understanding of a complex biological system, a wide spectrum of conceptual and experimental tools must be applied at different levels, from the molecular to the cellular, tissue and organismic. We believe the multifaceted regulatory interplay between integrin receptors and ion channels offers a rich and challenging field for researchers seeking broad biological perspectives. By mediating cell adhesion to the extracellular matrix,... Interdisciplinarity is more often invoked than practised. This is hardly surprising, considering the daunting vastness of modern biology. To reach ... |
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Diseases of DNA Repair
ISBN: 9781441964472 / Angielski / Twarda / 256 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Since this book is geared to be used by varied groups of readers such as advanced students and instructors in the fields of biology and medicine, scientists and more importantly clinicians, it is considered important to provide brief accounts of the basics of DNA damage, repair, mutagenesis and cancer. The purpose of this book is to present an updated detailed account of some important additional diseases of DNA repair. It has not been possible to cover all the DNA repair deficient diseases in this volume, hence diseases such as Bloom's syndrome, Werner's syndrome, Nijmegen breakage syndrome,...
Since this book is geared to be used by varied groups of readers such as advanced students and instructors in the fields of biology and medicine, scie...
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Advances in Bioinformatics: 4th International Workshop on Practical Applications of Computational Biology and Bioinformatics 2010 (Iwpacbb 2010)
ISBN: 9783642132131 / Angielski / Miękka / 240 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. The fields of Bioinformatics and Computational Biology have been growing steadily over the last few years boosted by an increasing need for computational techniques that can efficiently handle the huge amounts of data produced by the new experimental techniques in Biology. This calls for new algorithms and - proaches from fields such as Data Integration, Statistics, Data Mining, Machine Learning, Optimization, Computer Science and Artificial Intelligence. Also, new global approaches, such as Systems Biology, have been emerging replacing the reductionist view that dominated biological research...
The fields of Bioinformatics and Computational Biology have been growing steadily over the last few years boosted by an increasing need for computatio...
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Sequence Data Analysis Guidebook
ISBN: 9780896033580 / Angielski / Twarda / 324 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Computers have revolutionized the analysis of sequencing data. It is unlikely that any sequencing projects have been performed in the last few years without the aid of computers. Recently their role has taken a further major step forward. Computers have become smaller and more powerful and the software has become simpler to use as it has grown in sophistication. This book reflects that change since the majority of packages described here are designed to be used on desktop computers. Computer software is now available that can run gels, collect data, and assess its accuracy. It can assemble,...
Computers have revolutionized the analysis of sequencing data. It is unlikely that any sequencing projects have been performed in the last few years w...
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Biosystems Engineering II: Linking Cellular Networks and Bioprocesses
ISBN: 9783642138652 / Angielski / Twarda / 166 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Comprises: Morphology of Filamentous Fungi: Linking Cellular Biology to Process Engineering Using Aspergillus niger, By Rainer Krull, Christiana Cordes, Harald Horn, Ingo Kampen, Arno Kwade, Thomas R. Neu, and Bernd Nortemann; -Multi-Scale Spatio-Temporal Modeling: Lifelines of Microorganisms in Bioreactors and Tracking Molecules in Cells, By Alexei Lapin, Michael Klann, and Matthias Reuss; -Impact of Profiling Technologies in the Understanding of Recombinant Protein Production, By Chandran Vijayendran and Erwin Flaschel -Engineering the Escherichia coli Fermentative Metabolism, By M....
Comprises: Morphology of Filamentous Fungi: Linking Cellular Biology to Process Engineering Using Aspergillus niger, By Rainer Krull, Christiana Corde...
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Structures and Organelles in Pathogenic Protists
ISBN: 9783642128622 / Angielski / Twarda / 324 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Parasitic protozoa, including agents of human and veterinary disease, have special cytoplasmic structures and organelles. This work examines cytoskeletal structures such as the trichomonads mastigont system and sub-pellicular microtubules in trypanosomatids. Parasitic protozoa, including agents of human and veterinary disease, have special cytoplasmic structures and organelles. This work examines cytosk... |
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In Vivo Models of Inflammation
ISBN: 9783764377588 / Angielski / Twarda / 410 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. In Vivo Models of Inflammation (Vol. 1 and Vol. 2) provides biomedical researchers in both the pharmaceutical industry and academia with a description of the state-of-the-art animal model systems used to emulate diseases with components of inflammation. This second edition acts as a complement to the first, describing and updating the standard models that are most utilized for specific disease areas. New models are included exploring emerging areas of inflammation research. In Vivo Models of Inflammation (Vol. 1 and Vol. 2) provides biomedical researchers in both the pharmaceutical industry and academia with a descript... |
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Cell and Organ Printing
ISBN: 9789048191444 / Angielski / Twarda / 260 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Most successful research fields will go through different stages of development before maturation and eventually gain general acceptance. In the course of this development, it is important to periodically examine current progress, refocus goals, and explore new directions in the field. We believe the field of Cell-Printing (CP) has reached a stage when such an exercise is beneficial for all researchers involved. A number of the CP techniques have reached certain successes in the laboratory and it is time to examine their current capabilities and limitations, and establish... Most successful research fields will go through different stages of development before maturation and eventually gain general acceptance. In... |
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Coordination in Human and Primate Groups
ISBN: 9783642153549 / Angielski / Twarda / 304 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Coordination in Human and Primate Groups presents one of the first collections of the different approaches and methods used to assess coordination processes in groups. Written by psychologists and primatologists, the book represents a broad range of coordination research fields such as social psychology, work and organizational psychology, medicine, primatology, and behavioural ecology. It is designed for researchers and practitioners interested in understanding the behavioural aspects of group coordination. Coordination in Human and Primate Groups presents one of the first collections of the different approaches and methods used to assess coordination ... |
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Development of the Inner Ear
ISBN: 9781441920409 / Angielski / Miękka / 242 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. The Springer Handbook of Auditory Research presents a series of compreh- sive and synthetic reviews of the fundamental topics in modern auditory - search. The volumes are aimed at all individuals with interests in hearing research including advanced graduate students, postdoctoral researchers, and clinical investigators. The volumes are intended to introduce new investigators to important aspects of hearing science and to help established investigators to betterunderstandthefundamentaltheoriesanddatain?eldsofhearingthatthey may not normally follow closely. Each volume presents a particular...
The Springer Handbook of Auditory Research presents a series of compreh- sive and synthetic reviews of the fundamental topics in modern auditory - sea...
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Computational Methods for Protein Structure Prediction and Modeling: Volume 1: Basic Characterization
ISBN: 9781441922052 / Angielski / Miękka / 396 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. An ultimate goal of modern biology is to understand how the genetic blueprint of cells(genotype)determinesthestructure, function, andbehaviorofalivingorganism (phenotype). At the center of this scienti?c endeavor is characterizing the bioch- ical and cellular roles of proteins, the working molecules of the machinery of life. A key to understanding of functional proteins is the knowledge of their folded str- tures in a cell, as the structures provide the basis for studying proteins' functions and functional mechanisms at the molecular level. Researchers working on structure determination have...
An ultimate goal of modern biology is to understand how the genetic blueprint of cells(genotype)determinesthestructure, function, andbehaviorofaliving...
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Computational Methods for Protein Structure Prediction and Modeling: Volume 2: Structure Prediction
ISBN: 9781441922069 / Angielski / Miękka / 322 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Volume Two of this two-volume sequence presents a comprehensive overview of protein structure prediction methods and includes protein threading, De novo methods, applications to membrane proteins and protein complexes, structure-based drug design, as well as structure prediction as a systems problem. A series of appendices review the biological and chemical basics related to protein structure, computer science for structural informatics, and prerequisite mathematics and statistics. Volume Two of this two-volume sequence presents a comprehensive overview of protein structure prediction methods and includes protein threading, De... |
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Vertebrate Hair Cells
ISBN: 9781441929082 / Angielski / Miękka / 458 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Vertebrate Hair Cells provides a current overview of the mechanosensory receptor cells of the vertebrate inner ear. Each chapter is written by experimentalists active in exploring a particular set of questions in an aspect of hair cell function, including development, transduction, and synaptic transmission. Experimental approaches described include molecular, genetic, ultrastructural, biophysical and computational. Thus, each chapter covers not just what we know, but how we have learned it and the implications for future work. The experimental focus differentiates this book from general... Vertebrate Hair Cells provides a current overview of the mechanosensory receptor cells of the vertebrate inner ear. Each chapter is written by expe... |
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Microglia in the Regenerating and Degenerating Central Nervous System
ISBN: 9781441929440 / Angielski / Miękka / 315 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Over the past decade, the study of microglial cells has gained increasing importance, in particular for those working in the fields of degeneration and regeneration. Microglia in the Regenerating and Degenerating CNS supports the assertion that understanding microglial biology could perhaps be pivotal for unraveling the pathogenetic mechanisms that underlie Alzheimer's disease, currently the most widely studied disorder of the central nervous system. In addition, microglia are also critical for understanding the sequelae of traumatic brain and spinal cord injury, and for the vitally important...
Over the past decade, the study of microglial cells has gained increasing importance, in particular for those working in the fields of degeneration an...
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The Genetic Code and the Origin of Life
ISBN: 9781441934130 / Angielski / Miękka / 254 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Early Thoughts on RNA and the Origin of Life The full impact of the essential role of the nucleic acids in biological systems was forcefully demonstrated by the research community in the 1950s. Although Avery and his collaborators had identified DNA as the genetic material responsible for the transformation of bacteria in 1944, it was not until the early 1950s that the Hershey-Chase experiments provided a more direct demonstration of this role. Finally, the structural DNA double helix proposed by Watson and Crick in 1953 clearly created a structural frame work for the role of DNA as both...
Early Thoughts on RNA and the Origin of Life The full impact of the essential role of the nucleic acids in biological systems was forcefully demonstra...
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Zinc Finger Proteins: From Atomic Contact to Cellular Function
ISBN: 9781441934345 / Angielski / Miękka / 276 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. In the early 1980s, a few scientists started working on a Xenopus transcription factor, TFIIIA. They soon discovered a novel domain associated with zinc, and named this domain "zinc finger. " Th e number of proteins with similar zinc fingers grew quickly and these proteins are now called C2H2, Cys2His2 or classical zinc finger proteins. To date, about 24,000 C2H2 zinc finger proteins have been recognized. Approximately 700 human genes, or more than 2% of the genome, have been estimated to encode C2H2 finger proteins. From the beginning these proteins were thought to be numerous, but no one...
In the early 1980s, a few scientists started working on a Xenopus transcription factor, TFIIIA. They soon discovered a novel domain associated with zi...
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Toll and Toll-Like Receptors:: An Immunologic Perspective
ISBN: 9781441934383 / Angielski / Miękka / 218 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Toll Receptors and the Renaissance of Innate Immunity Elizabeth H. Bassett and Tina Rich Overview n the last few pages of Immunology: The Science of Self-Nonself Discrimination Jan Klein ponders on what he would study if he were to start over in the lab. DEGREES Dismissing the I antibody, MHC, the T-cell and parasitology, he considers instead the phylogeny of immune reactions, particularly in ancient phyla. As for a favored cell he chooses the macrophage. Describ ing it as a DEGREES DEGREESMddchenfUr alles," (all purpose kitchen maid) Klein believed that this immunocyte still had secrets to...
Toll Receptors and the Renaissance of Innate Immunity Elizabeth H. Bassett and Tina Rich Overview n the last few pages of Immunology: The Science of S...
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Rise and Fall of Epithelial Phenotype: Concepts of Epithelial-Mesenchymal Transition
ISBN: 9781441934390 / Angielski / Miękka / 248 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Epithelial phenotype is a dynamic stage of differentiation that can be modulated during several physiological or pathological events. The rapid conversion to a mesenchymal-like phenotype is called an epithelial-mesenchymal transition (EMT). The Rise and Fall of Epithelial Phenotype is the first book to comprehensively introduce the concept of EMT. The first part of this volume describes main examples and models and explains their physiological relevance. These examples include hydra morphogenesis, gastrulation in mouse, drosophila and sea urchin, as well as neural... Epithelial phenotype is a dynamic stage of differentiation that can be modulated during several physiological or pathological events. The rapid con... |
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Coronavirus Replication and Reverse Genetics
ISBN: 9783642059971 / Angielski / Miękka / 257 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Human coronaviruses caused the SARS epidemic that infected more than 8000 people, killing about ten percent of them in 32 countries. This book provides essential information on these viruses and the development of vaccines to control coronavirus infections. Human coronaviruses caused the SARS epidemic that infected more than 8000 people, killing about ten percent of them in 32 countries. This book prov... |
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Optical Polarization in Biomedical Applications
ISBN: 9783642065255 / Angielski / Miękka / 281 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. This study introduces key developments in optical polarization methods for quantitative studies of tissues, while presenting the theory of polarization transfer in a random medium as a basis for the quantitative description of polarized light interaction with tissues.
This study introduces key developments in optical polarization methods for quantitative studies of tissues, while presenting the theory of polarizatio...
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