Kategoria BISAC: Science >> Life Sciences - Biochemistry

Sets forth an important group of environmentally friendly organic reactions

With contributions from leading international experts in organic synthesis, this book presents all the most important methodologies for stereoselective organocatalysis, fully examining both the activation mode as well as the type of bond formed. Clear explanations guide researchers through all the most important methods used to form key chemical bonds, including carbon-carbon (C-C), carbon-nitrogen (C-N), and carbon-halogen (C-X) bonds. Moreover, readers will discover how the use of non-metallic...

Reflecting the important historical discoveries and exciting research in the field in recent years, Peroxidases and Catalases: Biochemistry, Biophysics, Biotechnology and Physiology provides a much-needed systematic, up-to-date treatment of peroxidases and catalases.

From the structure and properties of the various superfamilies to current applications of peroxidases, the book consolidates vast amounts of information previously scattered in the professional literature, covering all aspects of these ubiquitous enzymes...

Often considered the workhorse of the cellular machinery, proteins are responsible for functions ranging from molecular motors to signaling. The broad recognition of their involvement in all cellular processes has led to focused efforts to predict their functions from sequences, and if available, from their structures. An overview of current research directions, Computational Protein-Protein Interactions examines topics in the prediction of protein-protein interactions, including interference with protein-protein interactions and their design.

To harness the high-throughput potential of DNA microarray technology, it is crucial that the analysis stages of the process are decoupled from the requirements of operator assistance. Microarray Image Analysis: An Algorithmic Approach presents an automatic system for microarray image processing to make this decoupling a reality. The proposed system integrates and extends traditional analytical-based methods and custom-designed novel algorithms.

The book first explores a new technique that takes advantage of a multiview approach to image...

The rapid expansion of the TRP field has generated a large amount of excellent original work across many different research fields. However, investigators are not necessarily familiar with the pros and cons of the variety of methods used to study TRP channels. Because of functional and genetic diversity, as well as the different physiological roles they play, techniques used for studying TRP channels range from single molecular analysis to behavioral animal studies. Methods in multiple areas, such as molecular biology, fluorescence imaging, electrophysiology, cell biology, genetics,...

The Affymetrix GeneChip^(r) system is one of the most widely adapted microarray platforms. However, due to the overwhelming amount of information available, many Affymetrix users tend to stick to the default analysis settings and may end up drawing sub-optimal conclusions. Written by a molecular biologist and a biostatistician with a combined decade of experience in practical expression profiling experiments and data analyses, Gene Expression Studies Using Affymetrix Microarrays tears down the omnipresent language barriers among molecular biology, bioinformatics,...

Recent research demonstrates that defects in the processing mechanisms of small non-coding RNAs are linked to various human diseases. This text explores the latest research on microRNAs and their functional roles in cells and organisms. Written by international experts, discussion will include the identification, characterization, and structure-function analysis of microRNAs; the study of microRNAs in development, cancer, and viruses; and the applications of microRNAs with respect to gene regulation, functional genomics and therapeutics. This book is a valuable reference for established...

Natural products in the plant and animal kingdom offer a huge diversity of chemical structures that are the result of biosynthetic processes that have been modulated over the millennia through genetic effects. With the rapid developments in spectroscopic techniques and accompanying advances in high-throughput screening techniques, it has become possible to isolate and then determine the structures and biological activity of natural products rapidly, thus opening up exciting opportunities in the field of new drug development to the pharmaceutical industry.

The series also covers the...

Natural products in the plant and animal kingdom offer a huge diversity of chemical structures that are the result of biosynthetic processes that have been modulated over the millennia through genetic effects. With the rapid developments in spectroscopic techniques and accompanying advances in high-throughput screening techniques, it has become possible to isolate and then determine the structures and biological activity of natural products rapidly, thus opening up exciting opportunities in the field of new drug development to the pharmaceutical industry.

The series also covers the...

Natural products present in the plant and animal kingdom offer a huge diversity of chemical structures, which are the result of biosynthetic processes that have been modulated over the millennia through genetic effects. With the rapid developments in spectroscopic techniques and accompanying advances in high-throughput screening techniques, it has become possible to isolate and then determine the structures and biological activity of natural products rapidly, thus opening up to the pharmaceutical industry exciting opportunities in the field of new drug development. The series covers all of...

Studies in Natural Products Chemistry contains the latest articles written by leading authorities in their respective fields of research, presenting current frontiers and future guidelines for research based on important discoveries made in the field of bioactive natural products. It is an invaluable resource for anyone working in natural product and medicinal chemistry.

• Focuses on the chemistry of bioactive natural products
• Contains contributions by leading authorities in the field
• Presents sources of new pharmacophores

Studies in Natural Products Chemistry, Volume 48, provides the latest on the use of natural products from the plant and animal kingdom and the ways in which they can offer a huge diversity of chemical structures, which are the result of biosynthetic processes that have been modulated over the millennia through genetic effects.

With the rapid developments in spectroscopic techniques and accompanying advances in high-throughput screening techniques, it has become possible to isolate and then rapidly determine the structures and biological activity of natural products, thus...