Studies in Natural Products Chemistry: Volume 44

ISBN-13: 9780444634603 / Angielski / Twarda / 2015 / 552 str.

Atta-ur-Rahman

Opis

Natural products in the plant and animal kingdom offer a huge diversity of chemical structures that are the result of biosynthetic processes that have been modulated over the millennia through genetic effects. With the rapid developments in spectroscopic techniques and accompanying advances in high-throughput screening techniques, it has become possible to isolate and then determine the structures and biological activity of natural products rapidly, thus opening up exciting opportunities in the field of new drug development to the pharmaceutical industry. The series also covers the synthesis or testing and recording of the medicinal properties of natural products, providing cutting edge accounts of the fascinating developments in the isolation, structure elucidation, synthesis, biosynthesis and pharmacology of a diverse array of bioactive natural products.

• Focuses on the chemistry of bioactive natural products
• Contains contributions by leading authorities in the field
• Presents sources of new pharmacophores

Spis treści

1. Terpenoids and Sterols from Mushrooms, Yasunori Yaoita, Masao Kikuchi and Koichi Machida 2. From Bench to Bed Side: Natural Products and Analogues for the Treatment of Neglected Tropical Diseases (NTDs), Simone Kobe De Oliveira, Louise Domeneghini, Chiaradia-Delatorre, Alessandra Mascarello, Beatriz Veleirinho, Fernanda Ramlov, Shirley Kuhnen, Rosendo Augusto Yunes and Marcelo Maraschin3. Febrifugine and Its Analogues: Studies for Their Anti-Malarial and Other Therapeutic Properties, Sanjoy Singh Ningthoujam, Anupam Das Talukdar, Deepa Nath, Norazah Basar, Kumar Singh Potsangbam and Manabendra Dutta Choudhury 4. Macrocyclic N-Methylated Cyclic Peptides and Depsipeptides, Rani Maharani, Brad E. Sleebs and Andrew B. Hughes 5. Anticancer Drugs and Potential Anticancer Leads Inspired by Natural Products, Prasat Pittakoop6.Synthetic Aspects of Brassinosteroids, Vladimir A. Khripach, Vladimir N. Zhabinskii and Yuri V. Ermolovich7. The Chemistry and Bioactivity of Macrolides from Marine Microorganisms, Qing-Ai Liu, Juan-Juan Zheng, Yu-Cheng Gu, Chang-Yun Wang and Chang-Lun Shao8. Protein Kinase Inhibitors from Microorganisms, P. Radhika, M. Murali Krishna Kumar, and K. Purna Nagasree9. Possible Anti-Parkinson's Disease Therapeutics from Nature: A Review, Abhijit Dey and Jitendra Nath De

O autorze

Atta-ur-Rahman, Professor Emeritus, International Center for Chemical and Biological Sciences (H. E. J. Research Institute of Chemistry and Dr. Panjwani Center for Molecular Medicine and Drug Research), University of Karachi, Pakistan, was the Pakistan Federal Minister for Science and Technology (2000-2002), Federal Minister of Education (2002), and Chairman of the Higher Education Commission with the status of a Federal Minister from 2002-2008. He is a Fellow of the Royal Society of London (FRS) and an UNESCO Science Laureate. He is a leading scientist with more than 1283 publications in several fields of organic chemistry.