Studies in Natural Products Chemistry: Volume 46

ISBN-13: 9780444634627 / Angielski / Twarda / 2015 / 568 str.

Atta-Ur-Rahman

Opis

Natural products present in the plant and animal kingdom offer a huge diversity of chemical structures, which are the result of biosynthetic processes that have been modulated over the millennia through genetic effects. With the rapid developments in spectroscopic techniques and accompanying advances in high-throughput screening techniques, it has become possible to isolate and then determine the structures and biological activity of natural products rapidly, thus opening up to the pharmaceutical industry exciting opportunities in the field of new drug development. The series covers all of the above as well as the synthesis, testing and recording of the medicinal properties of natural products. With articles written by leading authorities in their respective fields of research, Studies in Natural Products Chemistry, Volume 46 presents current frontiers and future guidelines for research based on important discoveries made in the field of bioactive natural products. It is a valuable resource for all those working in natural product and medicinal chemistry.

• Focuses on the chemistry of bioactive natural products
• Contains contributions by leading authorities in the field
• Presents sources of new pharmacophores

Spis treści

1. A Review of the Ecological Role of Chemical Defenses in Facilitating Biological Invasion by Marine Benthic Organisms, Bruno Gualberto Lages, Beatriz Grosso Fleury and Joel Christopher
2. Rational Approach to the Design of Bioactive Peptidomimetics: Recent Developments in Opioid Agonist Peptides, Adriano Mollica, Azzurra Stefanucci, Roberto Costante and Victor J. Hruby 
3. Structure-Activity Relationships in the Host-Defense Antimicrobial Peptides Defensins, Himanshu Sharma and Ramakrishanan Nagaraj
4. Developments in the Synthesis of 3-Acyltetramic Acid Natural Products, Hidemi Yoda, Masaki Takahashi, and Tetsuya Sengoku
5. Bioactive Alkaloids of Hallucinogenic Mushrooms, Piotr Pawel Wieczorek, Danuta Witkowska, Izabela Jasicka-Misiak, Anna Poliwoda, Milena Oterman and Katarzyna Zielinska
6. Steroidal Conjugates: Synthesis, Spectroscopic and Biological Studies, Tomasz Pospieszny
7. Recent Developments in the Synthesis of the Flavours and Fragrances of Terpenoid Origin, Stefano Serra
8. Recent Developments on the Synthesis and Applications of Natural Products-Inspired Spirooxindole Frameworks, Srinivasarao Arulananda Babu, Rayavarapu Padmavathi, Nayyar Ahmad Aslam and Vadla Rajkumar
9. Alkaloids: A Source of Anticancer Agents from Nature, Ajai Prakash Gupta, Pankaj Pandotra, Manoj Kushwaha, Rajni Sharma and Suphla Gupta
10. Recent Advances in the Chemistry and Biology of Natural Dimeric Quinones, Hidayat Hussain, Ahmed Al-Harrasi, Ivan R. Green, Ghulam Abbas and Ishtiaq Ahmed
11. Phytomelatonin: Searching for Plants with High Levels for Use as a Natural Nutraceutical, Marino B. Arnao and Josefa Hernández-Ruiz

O autorze

Atta-ur-Rahman, Professor Emeritus, International Center for Chemical and Biological Sciences (H. E. J. Research Institute of Chemistry and Dr. Panjwani Center for Molecular Medicine and Drug Research), University of Karachi, Pakistan, was the Pakistan Federal Minister for Science and Technology (2000-2002), Federal Minister of Education (2002), and Chairman of the Higher Education Commission with the status of a Federal Minister from 2002-2008. He is a Fellow of the Royal Society of London (FRS) and an UNESCO Science Laureate. He is a leading scientist with more than 1283 publications in several fields of organic chemistry.