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Alcoholism and Women
ISBN: 9781475788105 / Angielski / Miękka / 472 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. 'Solid, plausible, accurate and loaded with pertinent and highly referenced information regarding clinical and basic research in alcholism among women and ethnic groups...an essential text in the libraries of academicians, teachers, clinicians, researchers, and policy makers. The quality and scope of the work are groundbreaking, and it is convenient to have it all in one source.' -American Journal of Psychiatry Volume 12 highlights the remarkable evolution of alcoholism research during the last few years, focusing on gender in alcohol actions and consequences.
'Solid, plausible, accurate and loaded with pertinent and highly referenced information regarding clinical and basic research in alcholism among women...
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Erythrocytes as Drug Carriers in Medicine
ISBN: 9781489900463 / Angielski / Miękka / 150 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. The sixth meeting on the use of resealed annealed red blood cells was held in Irsee, Germany by the International Society for the Use of Resealed Erythrocytes (ISURE) on July 25-28, 1996. Although earlier meetings focused on the technology toward develop- ment of methods and standardization for efficient, consistent encapsulation, most of the present studies now are directed toward the application use of these carrier blood cells. Basic studies now have been directed toward exploration of commercial applications. In- deed, clinical trials were initiated to evaluate the dose-response curves...
The sixth meeting on the use of resealed annealed red blood cells was held in Irsee, Germany by the International Society for the Use of Resealed Eryt...
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Methods of Pesticide Exposure Assessment
ISBN: 9781489909756 / Angielski / Miękka / 224 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. This book is a summary of the presentations and discussions at the Workshop on Methods of Pesticide Exposure Assessment held in Ottawa, Canada, on October 5-8, 1993. The event was a joint effort of Health Canada and the North Atlantic Treaty Organisation and was officially supported by the United States Environmental Agency and the Organisation for Economic Co-operation and Development (OECD). The goal of the workshop was to examine current issues in the field of pesticide exposure assessment with the aim of reaching an internationally harmonized approach to methods of exposure assessment....
This book is a summary of the presentations and discussions at the Workshop on Methods of Pesticide Exposure Assessment held in Ottawa, Canada, on Oct...
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806,99 |
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Saponins Used in Traditional and Modern Medicine
ISBN: 9781489913692 / Angielski / Miękka / 606 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. ''A wealth of information...these two volumes will be immensely valuable to anyone having to deal with this difficult group of compounds.'' ---Biochemical Systematics and Ecology, from a review of Saponins Used in Traditional and Modern Medicine and Saponins Used in Food and Agriculture
''A wealth of information...these two volumes will be immensely valuable to anyone having to deal with this difficult group of compounds.'' ---Biochem...
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Models for Assessing Drug Absorption and Metabolism
ISBN: 9781489918659 / Angielski / Miękka / 444 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Pharmaceutical scientists in industry and academia will appreciate this single reference for its detailed experimental procedures for conducting biopharmaceutical studies. This well-illustrated guide allows them to establish, validate, and implement commonly used in situ and in vitro model systems. Chapters provide ready access to these methodologies for studies of the intestinal, buccal, nasal and respiratory, vaginal, ocular, and dermal epithelium as well as the endothelial and elimination barriers.
Pharmaceutical scientists in industry and academia will appreciate this single reference for its detailed experimental procedures for conducting bioph...
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Tumors of the Central Nervous System, Volume 4: Brain Tumors (Part 2)
ISBN: 9789400738300 / Angielski / Miękka / 386 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. This volume mainly contains information on the diagnosis, therapy, and prognosis of brain tumors. Insights on the understanding of molecular pathways involved in tumor biology are explained, which should lead to the development of effective drugs. Information on pathways (e.g., hedgehog) facilitates targeted therapies in cancer. Tumor models are also presented, which utilize expression data, pathway sensitivity, and genetic abnormalities, representing targets in cancer. For example, rat model of malignant brain tumors using implantation of doxorubicin with drug eluting beads for delivery is...
This volume mainly contains information on the diagnosis, therapy, and prognosis of brain tumors. Insights on the understanding of molecular pathways ...
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Delivery Systems for Peptide Drugs
ISBN: 9781475799620 / Angielski / Miękka / 370 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Recent years have seen enormous advances in the field of protein and peptide engineering and a greater understanding in the way in which biological response modifiers function in the body. It is now possible through the use of recombinant DNA techniques, or by solid phase protein synthesis, to produce significant quantities of a wide variety of regulatory agents that are therapeutically applicable. The list of these response modifiers expands almost daily to include interferons, macrophage activation factors, neuropeptides and agents that may have potential in cardiovascular disease,...
Recent years have seen enormous advances in the field of protein and peptide engineering and a greater understanding in the way in which biological re...
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The Biology of Taurine: Methods and Mechanisms
ISBN: 9781489904072 / Angielski / Miękka / 406 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. I was pleased and at the same time filled with some misgivings when Professors Alberto Giotti end Ryan Huxtable asked me to introduce this book. The book is the outcome of the Symposium held in Firenze-San Miniato (PI), October 6-9, 1986. The symposium was entitled "Sulfur Amino Acids, Peptides and Related Compounds" and was the 7th international symposium on taurine nd assooiated substances. It is always difficult to introduce, with the right brevity end emphasis, a topic which has been studied in depth by numerous experte. Nevertheless, I shall do my best to give a historical perspeotive of...
I was pleased and at the same time filled with some misgivings when Professors Alberto Giotti end Ryan Huxtable asked me to introduce this book. The b...
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New Risks: Issues and Management
ISBN: 9781489907615 / Angielski / Miękka / 716 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. This volume contains the proceedings of the 1986 annual meeting and conference of the Society for Risk Analysis. It provides a detailed view of both mature disciplines and emerging areas within the fields of health, safety, and environmental risk analysis as they existed in 1986. In selecting and organizing topics for this conference, we sought both (i) to identify and include new ideas and application areas that would be of lasting interest to risk analysts and to users of risk analysis results, and (ii) to include innovative methods and applications in established areas of risk analysis. In...
This volume contains the proceedings of the 1986 annual meeting and conference of the Society for Risk Analysis. It provides a detailed view of both m...
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The Steric Factor in Medicinal Chemistry: Dissymmetric Probes of Pharmacological Receptors
ISBN: 9781489923998 / Angielski / Miękka / 570 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. 'It is indeed the merit of Dr. Alan F. Casy to bring in these pages a clear and comprehensive view of medicinal stereochemistry, a discipline in which he has been active and successful for many years both as a teacher and a researcher. Written for graduate students and research workers in medicinal chemistry and pharmacology, this book will contribute significantly towards a better education of scientists by removing the fear of stereochemistry caused by ignorance, moderating the overconfidence of possible zealots, and outlining a broader context.'-from the foreword by Bernard Testa
'It is indeed the merit of Dr. Alan F. Casy to bring in these pages a clear and comprehensive view of medicinal stereochemistry, a discipline in whi...
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Heparin and Related Polysaccharides
ISBN: 9781489924469 / Angielski / Miękka / 376 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. This volume is a record of a meeting entitled "Heparin and Related Polysaccharides" that was held at the Biomedical Center, Uppsala, Sweden between 1-6 September 1991. The meeting was hosted by U. Lindahl, L. Kjellen and I. Bjork, who were helped in their preparations by a scientific advisory panel that included U. Abildgaard, B. Casu, E. Holmer and D. Lane. Altogether, 230 participants from 18 countries attended the meeting, and most were present to be included in a photograph, which is to be found at the end of this volume. The selection of presentations for inclusion in the Symposia of the...
This volume is a record of a meeting entitled "Heparin and Related Polysaccharides" that was held at the Biomedical Center, Uppsala, Sweden between 1-...
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Phytochemical Resources for Medicine and Agriculture
ISBN: 9781489925862 / Angielski / Miękka / 445 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. This book was tbe result of a symposium beld at tbe American Cbernical Society meeting in Miami Beacb, Florida, September 10-15, 1989. The symposium was jointly sponsored by Tbe Society for Economfc Botany and tbe American Cbernical Society Food and Natural Product sub division. Tbere were five speakers. During tbe social sessions (mostly over drinks in abotel room), it became obvious tbat, regardless of tbe discipline, we were all speaking tbe same language. Yet, prior to tbe symposium, only a few of tbe participants knew one anotber. We decided to expand tbe symposium into a book. The book...
This book was tbe result of a symposium beld at tbe American Cbernical Society meeting in Miami Beacb, Florida, September 10-15, 1989. The symposium w...
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Mammalian Transient Receptor Potential (Trp) Cation Channels: Volume II
ISBN: 9783319051604 / Angielski / Twarda / 565 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. In this fast moving field the main goal of this volume is to provide up-to-date information on the molecular and functional properties and pharmacology of mammalian TRP channels. Leading experts in the field describe properties of a single TRP protein/channel or portray more general principles of TRP function and important pathological situations linked to mutations of TRP genes or their altered expression. Thereby this volume on Transient Receptor Potential (TRP) Channels provides valuable information for readers with different expectations and backgrounds, for those who are...
In this fast moving field the main goal of this volume is to provide up-to-date information on the molecular and functional properties and phar...
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Optimization in Drug Discovery: In Vitro Methods
ISBN: 9781627037419 / Angielski / Twarda / 597 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Thoroughly revised and updated, Optimization in Drug Discovery: In Vitro Methods, Second Edition presents a wide spectrum of in vitro assays including formulation, plasma binding, absorption and permeability, cytochrome P450 (CYP) and UDP-glucuronosyltransferases (UGT) metabolism, CYP inhibition and induction, drug transporters, drug-drug interactions via assessment of reactive metabolites, genotoxicity, and chemical and photo-mutagenicity assays. Written for the Methods in Pharmacology and Toxicology series, chapters include introductions to their respective topics, lists of... Thoroughly revised and updated, Optimization in Drug Discovery: In Vitro Methods, Second Edition presents a wide spectrum of in vitro assays... |
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Development of Innovative Drugs Via Modeling with MATLAB: A Practical Guide
ISBN: 9783642397646 / Angielski / Twarda / 399 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. The development of innovative drugs is becoming more difficult while relying on empirical approaches. This inspired all major pharmaceutical companies to pursue alternative model-based paradigms. The key question is: How to find innovative compounds and, subsequently, appropriate dosage regimens? Written from the industry perspective and based on many years of experience, this book offers: - Concepts for creation of drug-disease models, introduced and supplemented with extensive MATLAB programs - Guidance for exploration and modification of these programs to enhance the... The development of innovative drugs is becoming more difficult while relying on empirical approaches. This inspired all major pharmaceutical compan... |
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Molecular Toxicology Protocols
ISBN: 9781627037389 / Angielski / Twarda / 646 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Molecular Toxicology Protocols, Second Edition aims to bring together a series of articles describing validated methods to elucidate specific molecular aspects of toxicology, the emphasis being on the application of molecular methods to genetic toxicology. The volume is divided into ten parts, roughly corresponding to the spectrum of biomarkers intermediate between exposure and disease outcomes as proposed in molecular epidemiology models. Subjects of these new chapters range from preparation of fluid specimens for analysis of cellular inflammatory responses to genotoxic insults to... Molecular Toxicology Protocols, Second Edition aims to bring together a series of articles describing validated methods to elucidate specifi... |
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Twenty Years of G-CSF: Clinical and Nonclinical Discoveries
ISBN: 9783034808040 / Angielski / Miękka / 478 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Granulocyte colony-stimulating factor (G-CSF or GCSF) is a secreted glycoprotein that stimulates the proliferation and differentiation of granulocyte precursor cells, and induces mobilization of peripheral blood progenitor cells from the bone marrow. Development of recombinant human G-CSF has had a profound impact on the treatment of many diseases, including severe chronic neutropenia and cancer, and has enabled peripheral stem cell transplantation to supplant bone marrow transplantation in the autologous setting. This Milestones in Drug Therapy volume describes the... Granulocyte colony-stimulating factor (G-CSF or GCSF) is a secreted glycoprotein that stimulates the proliferation and differentiation of granulocy... |
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Dietary Supplements: Toxicology and Clinical Pharmacology
ISBN: 9781468497267 / Angielski / Miękka / 410 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. A treasure trove of uncommon and reliable scientific and clinical information for the toxicity and usefulness of today's leading nonherbal dietary supplements. The supplements detailed were chosen for their popularity, toxicity, and the quantity and quality of information available. Each monograph discusses the history of the compound; its chemical structure; its current and promoted uses, sources, and chemical composition; and its toxicity, pharmacokinetics, and physiological role. Also presented are case reports of adverse effects and interactions, as well as information on reproductive...
A treasure trove of uncommon and reliable scientific and clinical information for the toxicity and usefulness of today's leading nonherbal dietary sup...
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Membrane Transporters as Drug Targets
ISBN: 9781475786316 / Angielski / Miękka / 530 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Because progress in the field of transporters has been extraordinary, this volume will focus on recent advances in our understanding of the structure, function, physiology, and molecular biology of membrane transporters. There will be an emphasis on transporters as molecular targets for drug delivery and disposition in the body.
Because progress in the field of transporters has been extraordinary, this volume will focus on recent advances in our understanding of the structure,...
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Stability and Characterization of Protein and Peptide Drugs: Case Histories
ISBN: 9781489912381 / Angielski / Miękka / 353 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. This volume attemptsto provide the formulation scientist with casehistories involving the use of therapeutic proteins and peptides that have been mar- keted or are under clinical testing. In previous volumes of this series, funda- mental theories and principles ofprotein characterization and stability were presented in depth by researchers in their fieldsofexpertise. The way from theory to practice isnot alwaysobvious and straightforward. There isa need for practical examples of how the principles and theories are put into use, specificallyin the development of a pharmaceutical product. It is...
This volume attemptsto provide the formulation scientist with casehistories involving the use of therapeutic proteins and peptides that have been mar-...
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806,99 |
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