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Cerebral Ischemia
ISBN: 9780896035409 / Angielski / Twarda / 278 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. The human brain represents about 2% of the body weight, yet it accounts for approximately 20% of aerobic metabolism. This high dependency on energy-consuming processes is mainly caused by the active transport of ions, which is necessary to compensate for the transmembrane ion currents that are part ofthe complex signaling processes in the brain. Ninety-five percent ofthe brain's ATP is derived from mitochondrial oxidative phosphorylation. Since that organ' s storage capacity for oxygen is minimal, any interruption of oxygen delivery to brain cells willlead to changes in membrane excitability...
The human brain represents about 2% of the body weight, yet it accounts for approximately 20% of aerobic metabolism. This high dependency on energy-co...
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cena:
401,58 |
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Neurosteroids: A New Regulatory Function in the Nervous System
ISBN: 9780896035454 / Angielski / Twarda / 378 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Etienne-Emile Baulieu, the discoverer of neurosteroids, and a panel of distinguished scientists and clinical researchers exhaustively and critically review all facets of neurosteroids involved in behavior, stress, memory, depression, anxiety, aging of the brain, and neurodegenerative diseases. These contributors illuminate the role of neurosteroids in brain development and plasticity and detail their neuromodulatory influence on GABAA, ionotropic glutamate receptors, acetylcholine receptors, sigma receptors, and calcium channels. Clearly pointing the way toward novel pharmaceutical agents...
Etienne-Emile Baulieu, the discoverer of neurosteroids, and a panel of distinguished scientists and clinical researchers exhaustively and critically r...
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cena:
803,21 |
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Neuroglia in the Aging Brain
ISBN: 9780896035942 / Angielski / Twarda / 513 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. A distinguished panel of internationally recognized neuroscientists comprehensively review the involvement of and changes in glial cells both during the normal aging process and in the major disorders of old age. Topics range from the cellular and molecular changes that occur with aging-especially aging-associated activation of astrocytes and microglia and its relation to neuronal injury and repair-to neuron-glia intercommunication. The contributors show how glial signals may be modulated by hormones, growth factors, neurotransmitters, intracellular metabolism, and intercellular exchanges, as...
A distinguished panel of internationally recognized neuroscientists comprehensively review the involvement of and changes in glial cells both during t...
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cena:
803,21 |
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Adrenergic Receptor Protocols
ISBN: 9780896036024 / Angielski / Twarda / 577 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Adrenergic receptors are important modulators in the sympathetic c- trol of various metabolic processes in the central and peripheral nervous s- tems. These receptors are localized at multiple sites throughout the central nervous system (CNS) and serve as important regulators of CNS-mediated behavior and neural functions, including mood, memory, neuroendocrine c- trol, and stimulation of autonomic function. Adrenergic Receptor Protocols consists of 35 chapters dealing with va- ous aspects of adrenergic receptor analyses, including the use of genetic, RNA, protein expression, transactivator,...
Adrenergic receptors are important modulators in the sympathetic c- trol of various metabolic processes in the central and peripheral nervous s- tems....
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cena:
602,40 |
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Cerebral Signal Transduction: From First to Fourth Messengers
ISBN: 9780896036086 / Angielski / Twarda / 428 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Since the pioneering discovery of cyclic AMP four decades ago, a multitude of signaling pathways have been uncovered in which an extracellular signal (first messenger) impacts the cell surface, thereby triggering a cascade that ultimately acts on the cell nucleus. In each cascade the first messenger gives rise to the appearance of a second messenger such as cyclic AMP, cyclic GMP, or diacylglycerol, which in turn triggers a third messenger, a fourth messenger, and so forth. Many advances in elucidating such pathways have been made, including efforts to link messenger molecules to brain...
Since the pioneering discovery of cyclic AMP four decades ago, a multitude of signaling pathways have been uncovered in which an extracellular signal ...
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cena:
602,40 |
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The Nervous System and the Heart
ISBN: 9780896036932 / Angielski / Twarda / 564 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Gert Ter Horst and a panel of recognized experts illuminate the complexities and importance of heart-brain and brain-heart interactions in human health. These distinguished authorities critically review what is known about autonomic control of the heart, hypothalamo-pituitary- adrenal modulation, heart pain, modulation by humoral factors, and the relationship between cognitive/neuropsychiatric disorders and heart disease. Highly relevant and up-to-date, The Nervous System and the Heart offers the first comprehensive treatment of the important mutual interactions of the heart and the brain. By...
Gert Ter Horst and a panel of recognized experts illuminate the complexities and importance of heart-brain and brain-heart interactions in human healt...
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cena:
722,88 |
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Mitochondrial Inhibitors and Neurodegenerative Disorders
ISBN: 9780896038059 / Angielski / Twarda / 314 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Mitochondria have long been the Rodney Dangerfield of cellular organelles. Believed to be the remnants of bacterial infection of eukaryotic cells eons ago, the mitochondrion evolved a symbiotic relationship in which it dutifully served as the efficient source of A TP for cell function. The extraordinary dependence of cells on the energy provided by mito chondrial oxidative metabolism of glucose, especially through critical organs such as the heart and brain, is underlined by the fatal consequences of toxins that interfere with the mitochondrial electron transport system. Consistent with their...
Mitochondria have long been the Rodney Dangerfield of cellular organelles. Believed to be the remnants of bacterial infection of eukaryotic cells eons...
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cena:
602,40 |
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Pathogenesis of Neurodegenerative Disorders
ISBN: 9780896038387 / Angielski / Twarda / 294 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. As the average life expectancy of many populations throughout the world increases, so to does the incidence of such age-related neurodegenerative disorders as Alzheimer's, Parkinson's, and Huntington's diseases. Rapid advances in our understanding of the molecular genetics and environmental factors that either cause or increase risk for age-related neurodegenerative disor ders have been made in the past decade. The ability to evaluate, at the cellular and molecular level, abnormalities in postmortem brain tissue from patients, when taken together with the development of valuable animal and...
As the average life expectancy of many populations throughout the world increases, so to does the incidence of such age-related neurodegenerative diso...
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cena:
803,21 |
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The Neuronal Environment: Brain Homeostasis in Health and Disease
ISBN: 9780896038820 / Angielski / Twarda / 432 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Leading neuroscience researchers offer a fresh perspective on neuronal function by examining all its many components-including their pertubation during major disease states-and relate each element to neuronal demands. Topics range from the dependency of neurons on metabolic supply, as well as on both ion and transmitter homeostasis, to their close interaction with the myelin sheath. Also addressed are the astrocytic signaling system that controls synaptic transmission, the extracellular matrix and space as communication systems, the role of blood flow regulation in neuronal demand and in...
Leading neuroscience researchers offer a fresh perspective on neuronal function by examining all its many components-including their pertubation durin...
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cena:
803,21 |
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Stem Cells and CNS Development
ISBN: 9780896038868 / Angielski / Twarda / 370 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Stem Cells and CNS Development critically reviews recent findings on stem cells, their involvement in neurogenesis and gliogenesis, and the therapeutic implications of these findings. It defines by consensus the classes of stem cells in the nervous system, compares their similarities and differences, discusses the gains made in identifying human homologs of neural stem cells, and describes how these cells are beginning to be used
for therapeutic purposes. Comprehensive and cutting-edge, this book provides all developmental scientists and neurobiologists not only an authoritative account... Stem Cells and CNS Development critically reviews recent findings on stem cells, their involvement in neurogenesis and gliogenesis, and the therapeuti...
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cena:
602,40 |
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Immunosuppressant Analogs in Neuroprotection
ISBN: 9780896039445 / Angielski / Twarda / 378 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. An authoritative survey of the most recent scientific evidence showing how cyclosporin, FK-506, and their analogs-the neuroimmunophilins-evolved from being purely immunosuppressant "drugs" to neuroprotective "agents." The book focuses on recent preclinical evidence that demonstrates the neurotrophic/neuroprotective effects of immunosuppressants when administered alone or when combined with neural transplantation therapy in animal models of neurological disorders. It also discusses their efficacy and mechanisms of action in vitro and in vivo models of CNS disease, and provides laboratory...
An authoritative survey of the most recent scientific evidence showing how cyclosporin, FK-506, and their analogs-the neuroimmunophilins-evolved from ...
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cena:
602,40 |
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Neurotransmitter Transporters: Structure, Function, and Regulation
ISBN: 9780896039452 / Angielski / Twarda / 518 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Neurotransmission is a multicomponent process. Transmitters, released by neuronal activity, act on pre- and postsynaptic receptors, and many books detail advances in the receptor field. In addition, after their release from nerve endings, transmitters are removed from the neuronal vicinity by uptake into neuronal or glial cells by specific tra- porter proteins that have been studied intensely over the last 30 years; this information is scattered throughout numerous publishing vehicles. Therefore, the primary aim of this second edition of N- rotransmitter Transporters: Structure, Function, and...
Neurotransmission is a multicomponent process. Transmitters, released by neuronal activity, act on pre- and postsynaptic receptors, and many books det...
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cena:
803,21 |
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Neurogenetics: Methods and Protocols
ISBN: 9780896039902 / Angielski / Twarda / 390 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. The rapid identification and characterization of genes of neurological relevance holds great potential for offering insight into the diagnosis, management, and und- standing of the pathophysiologic mechanisms of neurological diseases. This volume in the Methods in Molecular Biology series was conceived to highlight many of the contemporary methodological approaches utilized for the characterization of neu- logically relevant gene mutations and their protein products. Although an emphasis has been placed upon descriptions of methodologies with a defined clinical utility, it is hoped that...
The rapid identification and characterization of genes of neurological relevance holds great potential for offering insight into the diagnosis, manage...
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cena:
401,58 |
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Neuropsychological Rehabilitation: Proceedings of the Conference on Rehabilitation of Brain Damaged People: Current Knowledge and Future Directions, H
ISBN: 9780898383744 / Angielski / Twarda / 136 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. In early 1985 a grant from the Egmont Foundation made the establishment of the Center for Rehabilitation of Brain Damage in copenhagen possible. This meant the realization of a plan with which Anne-Lise Christensen had been occupied for years. Through her work in psychiatric and neurosurgical wards she had acquired a deep insight in the problems of the brain damage, and through visits to the leading centers within the field of brain damage rehabilitation she had become inti mately acquainted with the most modern trends in research and practice which was insufficiently devel oped in Denmark....
In early 1985 a grant from the Egmont Foundation made the establishment of the Center for Rehabilitation of Brain Damage in copenhagen possible. This ...
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cena:
401,58 |
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Role of RNA and DNA in Brain Function: A Molecular Biological Approach
ISBN: 9780898388145 / Angielski / Twarda / 322 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. There was once an old Chinese man working on a hill with a boy. On the plain, near the sea, rested the village, the inhabitants eagerly engaged in their daily activities. Suddenly, the old man noticed that a huge wave, far distant in the sea, was approaching the shore endangering all. The only safe place was the hill. So, he began waving his hands and screaming aloud, to no avail. The villagers were too busy with their own work and paid little heed to the old man, who was considered a bit eccentric. But soon flames were on the hill, the wheat fields ablaze. The old man had resorted to this...
There was once an old Chinese man working on a hill with a boy. On the plain, near the sea, rested the village, the inhabitants eagerly engaged in the...
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cena:
803,21 |
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Brain and Perception: Holonomy and Structure in Figural Processing
ISBN: 9780898599954 / Angielski / Twarda / 420 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Presented as a series of lectures, this important volume achieves four major goals: 1) It integrates the results of the author's research as applied to pattern perception -- reviewing current brain research and showing how several lines of inquiry have been converging to produce a paradigm shift in our understanding of the neural basis of figural perception. 2) It updates the holographic hypothesis of brain function in perception. 3) It emphasizes the fact that both distributed (holistic) and localized (structural) processes characterize brain function. 4) It portrays a neural systems...
Presented as a series of lectures, this important volume achieves four major goals: 1) It integrates the results of the author's research as applied t...
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cena:
702,94 |
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Neurosurgery Explained: A Basic and Essential Introduction
ISBN: 9780954881306 / Angielski / Miękka / 380 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. This excellent pocket guide is written with the neurosurgical resident in mind but is equally useful for students, nurses, and other health professionals.
This excellent pocket guide is written with the neurosurgical resident in mind but is equally useful for students, nurses, and other health profession...
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cena:
340,57 |
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Exploration of Cortical Function: Imaging and Modeling Cortical Population Coding Strategies
ISBN: 9781402004353 / Angielski / Twarda / 269 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Exploration of Cortical Function summarizes recent research efforts aiming at the revelation of cortical population coding and signal processing strategies. Topics include optical detection techniques of population activity in the sub-millimeter range, advanced methods for the statistical analysis of these data, and biologically inspired neuronal modeling techniques for population activities in the frameworks of optimal coding, statistical learning theory, and mean-field recurrent networks. Exploration of Cortical Function is unique in that it covers one complete branch of... Exploration of Cortical Function summarizes recent research efforts aiming at the revelation of cortical population coding and signal processing st... |
cena:
602,40 |
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Exploration of Cortical Function: Imaging and Modeling Cortical Population Coding Strategies
ISBN: 9781402004360 / Angielski / Miękka / 269 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Exploration of Cortical Function summarizes recent research efforts aiming at the revelation of cortical population coding and signal processing strategies. Topics include optical detection techniques of population activity in the sub-millimeter range, advanced methods for the statistical analysis of these data, and biologically inspired neuronal modeling techniques for population activities in the frameworks of optimal coding, statistical learning theory, and mean-field recurrent networks. Exploration of Cortical Function is unique in that it covers one complete branch of... Exploration of Cortical Function summarizes recent research efforts aiming at the revelation of cortical population coding and signal processing st... |
cena:
602,40 |
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The Brain from 25,000 Feet: High Level Explorations of Brain Complexity, Perception, Induction and Vagueness
ISBN: 9781402011764 / Angielski / Twarda / 330 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. In The Brain from 25,000 Feet, Mark A. Changizi defends a non-reductionist philosophy and applies it to a variety of problems in the brain sciences. Some of the key questions answered are as follows. Why do we see visual illusions, and why are illusions inevitable for any finite-speed vision machine? Why aren't brains universal learning machines, and what does the riddle of induction and its solution have to do with human learning and innateness? The author tackles such questions as why the brain is folded, and why animals have as many limbs as they do, explaining how these...
In The Brain from 25,000 Feet, Mark A. Changizi defends a non-reductionist philosophy and applies it to a variety of problems in the ...
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cena:
602,40 |