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wyszukanych pozycji: 24
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The Effect of Input Parameters on Structural Steel (Fe500D Steel)
ISBN: 9786139857609 / Angielski / Miękka / 2018 / 156 str. Termin realizacji zamówienia: ok. 10-14 dni roboczych. |
cena:
280,78 zł |
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Development of Compression Coated Colon Targeted 5-Fluorouracil Tablet
ISBN: 9783659221941 / Angielski / Miękka / 2012 / 112 str. Termin realizacji zamówienia: ok. 10-14 dni roboczych. The purpose of this study was to develop and evaluate a drug delivery system in vitro based on a compression coated tablet containing 5-fluorouracil (5-FU) in core and pectin Hydroxypropyl Methylcellulose (HPMC) mixture in coat layer. The main reason for selecting pectin was its biodegradation in colon by colonic flora. On other hand, high molecular weight HPMC increases mechanical strength of tablet coat around a drug core during its transportation in gastro-intestinal tract. Multiple regression analysis with two way ANOVA revealed that both factors had statistically significant influence...
The purpose of this study was to develop and evaluate a drug delivery system in vitro based on a compression coated tablet containing 5-fluorouracil (...
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cena:
222,26 zł |
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Design and Development of Sildenafil citrate Mouth dissolving film
ISBN: 9783659408366 / Angielski / Miękka / 2013 / 108 str. Termin realizacji zamówienia: ok. 10-14 dni roboczych. Oral drug delivery is the most widely utilized route of administration among the entire route that has been explored for the systemic delivery of drug via various pharmaceutical products of different dosage form. The conventional tablet seems to be most popular because of its ease of transportation and low manufacturing cost as compare to others but poor patient compliance with whom experienced swallowing difficulties. In response to this mouth dissolving drug delivery system (MDDs) were developed as an alternative to tablet, capsule and syrup. A variety of MDDs like Mouth dissolving tablets...
Oral drug delivery is the most widely utilized route of administration among the entire route that has been explored for the systemic delivery of drug...
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cena:
249,03 zł |
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Design and Development of Extended Release Tablet of Nicotinic acid
ISBN: 9783659151880 / Angielski / Miękka / 2012 / 120 str. Termin realizacji zamówienia: ok. 10-14 dni roboczych. Nicotinic acid (NA) as lipid lowering agent drug has not become a first-line treatment due to the strong side effect called flushing occurs when given in immediate release dosage form. The tablets were prepared by wet granulation method using HPMC K-15M, polymer as retardant and the prepared tablets of NA will remain intact up to 2 hrs in pH 1.2 due to Eudragit L 100-55 and its release is not only initiated but tact fully retarded up to 12 hrs and were found to be superior in physical properties,dissolution characteristics, and drug content uniformity. The drug release from the matrix tablet...
Nicotinic acid (NA) as lipid lowering agent drug has not become a first-line treatment due to the strong side effect called flushing occurs when given...
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cena:
267,62 zł |
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Mouth Dissolving Tablet of Olanzapine by Solid Dispersion Technique
ISBN: 9783659133084 / Angielski / Miękka / 2012 / 136 str. Termin realizacji zamówienia: ok. 10-14 dni roboczych. In the present investigation, solid dispersion of olanzapine has been prepared to improve its solubility. Further, using solid dispersion, mouth dissolving tablet was prepared to overcome the problem of swallowing. A Simplex Lattice design was applied using three factors, i.e. superdisintegrants like croscarmellose sodium(X1) crospovidone(X2), and sodium starch glycolate(X3) in tablet formulation. Disintegration time, Wetting time, Water absorption, T50 (Time required to 50% drug release) and Q10 (percentage of drug released in 10 min.) taken as responses. Solid dispersion showed significant...
In the present investigation, solid dispersion of olanzapine has been prepared to improve its solubility. Further, using solid dispersion, mouth disso...
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cena:
267,62 zł |
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Sustained Release Tablet of Itopride Hydrochloride
ISBN: 9783659151507 / Angielski / Miękka / 2012 / 128 str. Termin realizacji zamówienia: ok. 10-14 dni roboczych. Itopride, a novel prokinetic agent is unique and different from the available prokinetics because of its dual mode of action and lack of significant drug interaction potential. Itopride is a newly developed prokinetic agent, which enhances gastric motility through both anti-dopaminergic and anti-acetylcholinesterage actions. It is best candidate for Gastro Esophageal Reflux Disease. Itopride 50mg can be given thrice in a day for Treatment of GERD. By developing the sustain release formulation of Itopride hydrochloride, the frequency of drug can be reduce to once only to obtain good...
Itopride, a novel prokinetic agent is unique and different from the available prokinetics because of its dual mode of action and lack of significant d...
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cena:
267,62 zł |
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Design & Developement of Floating Tablet of Tolperisone Hydrochloride
ISBN: 9783659136061 / Angielski / Miękka / 2012 / 160 str. Termin realizacji zamówienia: ok. 10-14 dni roboczych. Tolperisone hydrochloride has a short elimination half- life and rapidly absorbed from gastrointestinal tract.2 If it is formulated by conventional tablets, it will require multiple daily administrations (2-3 times daily) which ultimately results into in conveniency to the patients and possibility of reduced compliance with prescribed therapy. Tolperisone HCl is more stable in acidic medium (pH > 4.5),and in alkaline medium (pH 4 to 7) tolperisone breaks down into 4-MMPPO and piperidine. Thus, the patient is exposed to an uncontrollable quantity of...
Tolperisone hydrochloride has a short elimination half- life and rapidly absorbed from gastrointestinal tract.2 If it is formulated by conventional ta...
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cena:
308,45 zł |
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Osmotic Drug Delivery of Verapamil Hydrochloride
ISBN: 9783659137198 / Angielski / Miękka / 2012 / 120 str. Termin realizacji zamówienia: ok. 10-14 dni roboczych. The objective of this study is to develop controlled porosity osmotic pump tablet of Verapamil Hydrochloride, which is an antihypertensive candidate, using Polyethylene glycol (PEG) 400 as pore former in Cellulose acetate semipermeable membrane and Mannitol as a osmotic agent which release drug for extended period of time (24 h) and drug release of optimized formulation is independent of pH and agitation speed with zero order release.
The objective of this study is to develop controlled porosity osmotic pump tablet of Verapamil Hydrochloride, which is an antihypertensive candidate, ...
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cena:
222,26 zł |
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Design and Development of Onion Grader
ISBN: 9783659507694 / Angielski / Miękka / 2013 / 136 str. Termin realizacji zamówienia: ok. 10-14 dni roboczych. Onion bulbs are graded manually at farm and trader level.Manual grading of onion is a labour consuming and tedious operation coming with many losses. Therefore, the modern technologies, like automatic grading systems, are of utmost need. Grading is one of the most important operations affecting onion export. It determines the size of standard sale package, thereby increasing marketing attractiveness, and simplifies the mechanization of different handling systems, such as cutting and peeling. There are different types of onion graders available in the Indian market. These are of higher...
Onion bulbs are graded manually at farm and trader level.Manual grading of onion is a labour consuming and tedious operation coming with many losses. ...
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cena:
280,78 zł |
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Design And Development of Alfuzosin HCL Floating Microspheres : Floating Microspheres of Alfuzosin HCl
ISBN: 9783659427886 / Angielski / Miękka / 2013 / 184 str. Termin realizacji zamówienia: ok. 10-14 dni roboczych. |
cena:
326,14 zł |
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Design and devlopement of floating tablet
ISBN: 9783659412813 / Angielski / Miękka / 2013 / 124 str. Termin realizacji zamówienia: ok. 10-14 dni roboczych. In the winter of 1951, a storyteller arrives at the home of nine-year-old Ronan OMara in the Irish countryside. The last practitioner of an honored, centuries-old tradition, the Seanchai enthralls his assembled audience for three evenings running with narratives of foolish kings and fabled saints, of enduring accomplishments and selfless acts -- until he is banished from the household for blasphemy and moves on. But these three incomparable nights have changed young Ronan forever, setting him on the course he will follow for years to come -- as he persues the elusive, itinerant story teller...
In the winter of 1951, a storyteller arrives at the home of nine-year-old Ronan OMara in the Irish countryside. The last practitioner of an honored, c...
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cena:
253,56 zł |
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Floating
ISBN: 9783659439834 / Angielski / Miękka / 2013 / 160 str. Termin realizacji zamówienia: ok. 10-14 dni roboczych. Floating in situ gelling system of Amoxicillin with increased gastric residence time can be formulated using Xanthan gum and Guar gum as a natural polymer. This floating in situ gel is based on the pH triggered and ion exchange. The optimized formulation F6 provided sustained in vitro release of drug over an extended period of time up to 12 hrs. The drug release from gel structure follows a zero order release.
Floating in situ gelling system of Amoxicillin with increased gastric residence time can be formulated using Xanthan gum and Guar gum as a natural pol...
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cena:
326,14 zł |
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Development of Self Microemulsifying Drug Delivery System
ISBN: 9783659404795 / Angielski / Miękka / 2013 / 108 str. Termin realizacji zamówienia: ok. 10-14 dni roboczych. Nearly 40% of new drug candidates exhibit low solubility in water, which leads to poor oral bioavailability, high intra- and inter-subject variability and lack of dose proportionality. Modification of the physicochemical properties, such as salt formation and particle size reduction of the compound may be one approach to improve the dissolution rate. . In recent years, much attention has focused on lipid based formulations to improve the oral bioavailability of poorly water soluble drug compounds. In fact, the most popular approach is the incorporation of the drug compound into inert lipid...
Nearly 40% of new drug candidates exhibit low solubility in water, which leads to poor oral bioavailability, high intra- and inter-subject variability...
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cena:
226,35 zł |
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Etudes Sur Le Stockage de l'Oignon Sous Ventilation Forcee
ISBN: 9786203780314 / Francuski Termin realizacji zamówienia: ok. 10-14 dni roboczych. |
cena:
267,62 zł |
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Estudos Sobre O Armazenamento Forcado de Cebola Ventilada Por AR
ISBN: 9786203780338 / Portugalski Termin realizacji zamówienia: ok. 10-14 dni roboczych. |
cena:
267,62 zł |
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Studi Sulla Conservazione Ventilata Ad Aria Forzata Della Cipolla
ISBN: 9786203780321 / Włoski Termin realizacji zamówienia: ok. 10-14 dni roboczych. |
cena:
267,62 zł |
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Formulation and Evaluation of Colon Targeted Aceclofenac Tablet
ISBN: 9783659150982 / Angielski / Miękka / 2012 / 116 str. Termin realizacji zamówienia: ok. 10-14 dni roboczych. The aim of the study was to develop and evaluate enteric coated matrix tablet of Aceclofenac for colonic delivery by exploiting prolonged release characteristics of HPMC K4M with pH dependent solubility property of a Eudragit S100. Extended release matrix tablet were prepared by direct compression of hydrophilic polymer HPMC and other ingredients. The pH dependent release was achieved by coating matrix tablet with Eudragit S100, soluble at pH 7. All the formulations of 32 factorial design (A1- A9) were evaluated for the physicochemical parameters and subjected to in vitro drug release in 0.1...
The aim of the study was to develop and evaluate enteric coated matrix tablet of Aceclofenac for colonic delivery by exploiting prolonged release char...
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cena:
222,26 zł |
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Development of Colon Targeted Hydrogel Tablet of Methotrexate
ISBN: 9783846544969 / Angielski / Miękka / 2012 / 128 str. Termin realizacji zamówienia: ok. 10-14 dni roboczych. Colorectal cancer is second leading cause of deaths in the United States. Various approaches available for The poor site specificity of pH dependent systems, because of large variation in the pH of gastrointestinal tract, was well established. The timed-release systems release their load after a predetermined period of administration. These are designed to resist the release of the drug in stomach and small intestine and release of the drug takes place in colon. Methotrexate (MTX) is a used in the treatment of colon cancer and now a days rheumatic disease. MTX is a folate antimetabolite. MTX...
Colorectal cancer is second leading cause of deaths in the United States. Various approaches available for The poor site specificity of pH dependent s...
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cena:
267,62 zł |
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Design and Development of Colon Targeted Drug Delivery System
ISBN: 9783847309765 / Angielski / Miękka / 2012 / 96 str. Termin realizacji zamówienia: ok. 10-14 dni roboczych. |
cena:
222,26 zł |
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Formulation & In-Vitro Evaluation of Tolperisone HCl Buoyant Tablet
ISBN: 9783659546297 / Angielski / Miękka / 2014 / 148 str. Termin realizacji zamówienia: ok. 10-14 dni roboczych. The present investigation was aimed to formulate and evaluate buoyant tablet of Tolperisone HCl were prepared by direct compression method based on natural polymers (e.g. Xanthan Gum and Guar Gum) as matrix forming material and different concentrtion of sodium bicarbonate as gas generating agent. Tolperisone HCl is a skeletal muscle relaxant. Drug is more stable in acidic medium (pH<4.5), and in alkaline medium Tolperisone breaks down into 4-MMPPO [2 methyl-1-(4methylphenyl)-propanone] and piperidine. Thus, the patient is exposed to an uncontrollable quantity of genotoxic agent 4-MMPPO. By...
The present investigation was aimed to formulate and evaluate buoyant tablet of Tolperisone HCl were prepared by direct compression method based on na...
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cena:
280,78 zł |
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