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Estimates of gene effects based on analysis of generation mean were obtained for nine traits in three crosses in castor (Ricinus communis L.): SKP-84 x DCS-94, VP-1 x DCS-94 and GEETA x GC-3. The study material includes P1, P2, F1, F2, BC1 and BC2 generations of these crosses.The individual scaling test and joint scaling test indicated that an additive-dominance model was adequate in three traits viz., length of main raceme, number of effective branches per plant and seed index in the cross VP-1 x DCS-94. The analysis showed the presence of additive, dominance and epistasis gene effects for...

Nearly 40% of new drug candidates exhibit low solubility in water, which leads to poor oral bioavailability, high intra- and inter-subject variability and lack of dose proportionality. Modification of the physicochemical properties, such as salt formation and particle size reduction of the compound may be one approach to improve the dissolution rate. . In recent years, much attention has focused on lipid based formulations to improve the oral bioavailability of poorly water soluble drug compounds. In fact, the most popular approach is the incorporation of the drug compound into inert lipid...