Kategoria BISAC: Science >> Research & Methodology

This book presents concise descriptions and analysis of the classical and modern models used in mathematical biophysics. The authors ask the question "what new information can be provided by the models that cannot be obtained directly from experimental data?" Actively developing fields such as regulatory mechanisms in cells and subcellular systems and electron transport and energy transport in membranes are addressed together with more classical topics such as metabolic processes, nerve conduction and heart activity, chemical kinetics, population dynamics, and photosynthesis. The main...

This book offers a complex analysis of the spatial aspects of scientific collaboration, addressing the topic at a number of levels: individual (personal), organizational, urban, regional, national, and international. Spatial patterns of scientific collaboration are analysed along with their determinants and consequences.

The examples of scientific collaboration policy discussed in the book are taken from three different settings: the European Union, the USA and China. Through a number of case studies the authors analyse the background, development and evaluation of these...

Reflecting over three decades of advances, Epidermal Cells: Methods and Protocols, Third Edition underscores these advances in our understanding of epidermal biology with updated and entirely new protocols that compliment and extend the earlier edition. The inclusion of protocols useful for both in vitro and in vivo studies reflects many useful developments in the field. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily...

This book builds upon a previously-successful 2008 conference and resulting 2010 Wiley book, Survey Methods in Multinational, Multiregional and Multicultural Contexts (Harkness), recent winner of the 2013 American Association of Public Opinion and Research (AAPOR) Book Award. It is the by-product of a similar conference, which was held eight years later. Since the 2008 conference, there have been substantial methodological, operational and technical advances in international survey research. There are also whole new areas of methodological development that were only on the horizon...

The emergence of systems biology raises many fascinating questions: What does it mean to take a systems approach to problems in biology? To what extent is the use of mathematical and computational modelling changing the life sciences? How does the availability of big data influence research practices? What are the major challenges for biomedical research in the years to come? This book addresses such questions of relevance not only to philosophers and biologists but also to readers interested in the broader implications of systems biology for science and society.

The book features...

Animal Cell Biotechnology: Methods and Protocols, Third Edition constitutes a comprehensive manual of state-of-the-art and new techniques for setting up mammalian cell lines for production of biopharmaceuticals, and for optimizing critical parameters for cell culture from lab to final production. The volume is divided into five parts that reflect the processes required for different stages of production. In Part I, basic techniques for establishment of production cell lines are addressed, especially high-throughput synchronization, insect cell lines, transient gene and protein...

Time and Methods in Environmental Interfaces Modelling: Personal Insights considers the use of time in environmental interfaces modeling and introduce new methods, from the global scale (e.g. climate modeling) to the micro scale (e.g. cell and nanotubes modeling), which primarily arise from the personal research insights of the authors.

As the field of environmental science requires the application of new fundamental approaches that can lead to a better understanding of environmental phenomena, this book helps necessitate new approaches in modeling, including category theory,...

"Information" is a word that is much used and discussed, but with little agreement on its meaning. Yet information forms the professional focus and intellectual content of numerous disciplines and professions---information science, knowledge management, social studies of information, digital humanities, biomedical informatics, library science, archival science, records management, information systems, and many more. In this collection of eighteen professional papers and other texts by Professor Marcia Bates, of UCLA's Department of Information Studies, this pivotal concept is addressed in...

In this review of the electrophysiology of extraocular muscle, Dr. Breinin gives particular attention to the scientific literature on ocular electromyography. This literature is quite recent but the bibliography is growing at a rapid rate. Fundamental advances in the knowledge of extraocular muscle function in health and disease have accrued in the investigations being conducted in many laboratories and the author provides a comprehensive summary of information on the theoretical and practical applications of electromyography to the extraocular muscles and the contributions of the...

Diverse molecular, cellular, and environmental events must all come together to allow the successful formation of secondary cancers, metastases. The second edition of Metastasis Research Protocols, brings together updated versions of the seminal technique that were presented in the first edition and also includes new techniques that have recently been shown to be important in illuminating the processes underlying this important area of biology. Volume 2 presents techniques applicable at the level of living cells and tissues, and presents methodologies applicable to cell...

Protein Design: Method and Applications, Second Edition expands upon the previous edition with current, detailed ideas on how to approach a potential protein design project. With new chapters on metals as structure-forming elements and functional sites, the design and characterization of fluorinated proteins, top-down symmetric deconstruction and the design of protein libraries and novel or repurposed enzymes. Written in the highly successful Methods in Molecular Biologyseries format, chapters include introductions to their respective topics, lists of the necessary materials...