Radiobiology and Environmental Security
ISBN: 9789400719996 / Angielski / Miękka / 388 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. This volume like the NATO Advanced Research Workshop on which it is based addresses the fundamental science that contributes to our understanding of the potential risks from ecological terrorism, i.e. dirty bombs, atomic explosions, intentional release of radionuclides into water or air. Both effects on human health (DNA and systemic effects) and on ecosystems are detailed, with particular focus on environmentally relevant low-dose ranges. The state-of-the-art contributions to the book are authored by leading experts; they tackle the relevant questions from the perspectives of radiation...
This volume like the NATO Advanced Research Workshop on which it is based addresses the fundamental science that contributes to our understanding of t...
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cena:
776,43 zł |
Lacrimal Gland, Tear Film, and Dry Eye Syndromes: Basic Science and Clinical Relevance
ISBN: 9780306446764 / Angielski / Twarda / 729 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. During the past decade a significant international research effort has been directed towards understanding the composition and regulation of the preocular tear film. This effort has been motivated by the recognition that the tear film plays an essential role in maintaining corneal and conjunctival integrity, protecting against microbial challenge and preserving visual acuity. In addition, research has been stimulated by the knowledge that alteration or deficiency of the tear film, which occurs in countless individuals throughout the world, may lead to desiccation of the ocular surface,...
During the past decade a significant international research effort has been directed towards understanding the composition and regulation of the preoc...
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cena:
1281,15 zł |
Cartographie Du Milieu Biophysique Du Parc National Des Deux Ballé
ISBN: 9786131566516 / Francuski / Miękka / 84 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Depuis le sommet de Bali en 1982, la gestion des parcs et de la biodiversitA(c) a connu une prise en compte effective dans les politiques et programmes nationaux. Qu''ils soient publics ou privA(c)s, les orientations et obligations de leur amA(c)nagement incombent aux autoritA(c)s publiques. Cela est particuliA]rement vrai pour les aires protA(c)gA(c)es des catA(c)gories de l''UICN. Car, si le but des AP reste la conservation, la gestion de la biodiversitA(c) et l''environnement, la finalitA(c) de leur crA(c)ation et gestion demeure le dA(c)veloppement durable des communautA(c)s riveraines....
Depuis le sommet de Bali en 1982, la gestion des parcs et de la biodiversitA(c) a connu une prise en compte effective dans les politiques et programme...
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cena:
178,13 zł |
Angewandte Biophysik
ISBN: 9783709108291 / Niemiecki / Miękka / 321 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Biophysik ist die Lehre von den physikalischen Vorgangen in lebenden Systemen bzw. die Anwendung physikalischer Verfahren auf biologische Objekte. Das Buch bietet eine Einfuhrung in anwendungsbezogene Probleme: molekulare Kommunikation, biophysikalische Analytik (von Rontgenanalyse bis Tunnelmikroskop), Neurobiophysik (von Synapsen bis zum Magnetfeld des Gehirns) sowie Wechselwirkungen (magnetische Separation, Licht und Mikrowellenstrahlung). Die Mathematik wird auf grundlegende Zusammenhange und die Abschatzung von Grossenordnungen beschrankt."
Biophysik ist die Lehre von den physikalischen Vorgangen in lebenden Systemen bzw. die Anwendung physikalischer Verfahren auf biologische Objekte. Das...
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cena:
235,82 zł |
Formation and Cooperative Behaviour of Protein Complexes on the Cell Membrane
ISBN: 9783642239878 / Angielski / Twarda / 80 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. With the aim of providing a deeper insight into possible mechanisms of biological self-organization, this thesis presents new approaches to describe the process of self-assembly and the impact of spatial organization on the function of membrane proteins, from a statistical physics point of view. It focuses on three important scenarios: the assembly of membrane proteins, the collective response of mechanosensitive channels and the function of the twin arginine translocation (Tat) system. Using methods from equilibrium and non-equilibrium statistical mechanics, general conclusions were drawn...
With the aim of providing a deeper insight into possible mechanisms of biological self-organization, this thesis presents new approaches to describe t...
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cena:
194,08 zł |
Kompendium Systembiologie: Mathematische Modellierung Und Modellanalyse
ISBN: 9783834819079 / Niemiecki / Miękka / 300 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Das Buch beschreibt die Grundlagen der mathematischen Modellierung zellularer Systeme. Nach einer Klassifikation von Modellen wird schwerpunktmassig auf deterministische Modelle eingegangen und fur alle relevanten zellularen Prozesse entsprechende Gleichungen angegeben. Anschliessend werden eine Reihe von Verfahren zur Modellanalyse vorgestellt. Etwas kurzer werden Verfahren zum Reverse Engineering und zur Analyse von Netzwerkgraphen abgehandelt. Am Ende werden noch Verfahren der Parameteridentifikation besprochen."
Das Buch beschreibt die Grundlagen der mathematischen Modellierung zellularer Systeme. Nach einer Klassifikation von Modellen wird schwerpunktmassig a...
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cena:
145,09 zł |
Vortex Formation in the Cardiovascular System
ISBN: 9781447122876 / Angielski / Twarda / 166 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Vortex Formation in the Cardiovascular System will recapitulate the current knowledge about the vortex formation in the cardiovascular system, from mechanics to cardiology. This can facilitate the interaction between basic scientists and clinicians on the topic of the circulatory system. The book begins with a synopsis of the fundamentals aspects of fluid mechanics to give the reader the essential background to address the proceeding chapters. Then the fundamental elements of vortex dynamics will be discussed, explaining the conditions for their formation and the rules governing their...
Vortex Formation in the Cardiovascular System will recapitulate the current knowledge about the vortex formation in the cardiovascular system, from me...
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cena:
582,32 zł |
Detection of Non-Amplified Genomic DNA
ISBN: 9789400712256 / Angielski / Twarda / 318 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. This book offers an overview of state-of-the-art in non amplified DNA detection methods and provides chemists, biochemists, biotechnologists and material scientists with an introduction to these methods. In fact all these fields have dedicated resources to the problem of nucleic acid detection, each contributing with their own specific methods and concepts. This book will explain the basic principles of the different non amplified DNA detection methods available, highlighting their respective advantages and limitations. Non-amplified DNA detection can be achieved by adopting different...
This book offers an overview of state-of-the-art in non amplified DNA detection methods and provides chemists, biochemists, biotechnologists and mater...
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cena:
388,20 zł |
The First Gene: The Birth of Programming, Messaging and Formal Control.
ISBN: 9780965798891 / Angielski / Miękka / 408 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. "The First Gene: The Birth of Programming, Messaging and Formal Control" is a peer-reviewed anthology of papers that focuses, for the first time, entirely on the following difficult scientific questions: *How did physics and chemistry write the first genetic instructions? *How could a prebiotic (pre-life, inanimate) environment consisting of nothing but chance and necessity have programmed logic gates, decision nodes, configurable-switch settings, and prescriptive information using a symbolic system of codons (three nucleotides per unit/block of code)? The codon table is formal, not physical....
"The First Gene: The Birth of Programming, Messaging and Formal Control" is a peer-reviewed anthology of papers that focuses, for the first time, enti...
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cena:
142,54 zł |
Handbook of Soil Sciences (Two Volume Set)
ISBN: 9781439803035 / Angielski / Twarda / 2272 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. An evolving, living organic/inorganic covering, soil is in dynamic equilibrium with the atmosphere above, the biosphere within, and the geology below. It acts as an anchor for roots, a purveyor of water and nutrients, a residence for a vast community of microorganisms and animals, a sanitizer of the environment, and a source of raw materials for construction and manufacturing. To develop lasting solutions to the challenges of balanced use and stewardship of the Earth, we require a fundamental understanding of soil from its elastic, porous three-phase system to its components, processes,... An evolving, living organic/inorganic covering, soil is in dynamic equilibrium with the atmosphere above, the biosphere within, and the geology bel... |
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cena:
991,22 zł |
Dynamics of Soft Matter: Neutron Applications
ISBN: 9781461407263 / Angielski / Twarda / 450 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Dynamics of Soft Matter: Neutron Applications provides an overview of neutron scattering techniques that measure temporal and spatial correlations simultaneously, at the microscopic and/or mesoscopic scale. These techniques offer answers to new questions arising at the interface of physics, chemistry, and biology. Knowledge of the dynamics at these levels is crucial to understanding the soft matter field, which includes colloids, polymers, membranes, biological macromolecules, foams, emulsions towards biological & biomimetic systems, and phenomena involving wetting, friction,... Dynamics of Soft Matter: Neutron Applications provides an overview of neutron scattering techniques that measure temporal and spatial correl... |
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cena:
776,43 zł |
Signaling at the Cell Surface in the Circulatory and Ventilatory Systems
ISBN: 9781461419907 / Angielski / Twarda / 982 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. The volumes in this authoritative series present a multidisciplinary approach to modeling and simulation of flows in the cardiovascular and ventilatory systems, especially multiscale modeling and coupled simulations. The cardiovascular and respiratory systems are tightly coupled, as their primary function is to supply oxygen to and remove carbon dioxide from the body's cells. Because physiological conduits have deformable and reactive walls, macroscopic flow behavior and prediction must be coupled to nano- and microscopic events in a corrector scheme of regulated mechanisms when the vessel... The volumes in this authoritative series present a multidisciplinary approach to modeling and simulation of flows in the cardiovascular and ventila... |
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cena:
582,32 zł |
Computational Modeling of Biological Systems: From Molecules to Pathways
ISBN: 9781461421450 / Angielski / Twarda / 366 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Computational modeling is emerging as a powerful new approach to study and manipulate biological systems. Multiple methods have been developed to model, visualize, and rationally alter systems at various length scales, starting from molecular modeling and design at atomic resolution to cellular pathways modeling and analysis. Higher time and length scale processes, such as molecular evolution, have also greatly benefited from new breeds of computational approaches. This book provides an overview of the established computational methods used for modeling biologically and medically relevant...
Computational modeling is emerging as a powerful new approach to study and manipulate biological systems. Multiple methods have been developed to mode...
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cena:
388,20 zł |
Molecular Theory of the Living Cell: Concepts, Molecular Mechanisms, and Biomedical Applications
ISBN: 9781461421511 / Angielski / Twarda / 748 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. The book presents the first comprehensive molecular theory of the living cell ever published since the cell doctrine was formulated in 1838-1839. It introduces into cell biology over three dozens of key concepts, principles and laws imported from physics, chemistry, computer science, linguistics, semiotics and philosophy. The author formulates physically, chemically and enzymologically realistic molecular mechanisms to account for basic living processes such as ligand-receptor interactions, enzymic catalysis, force-generating mechanisms in molecular motors, chromatin remodelling, and... The book presents the first comprehensive molecular theory of the living cell ever published since the cell doctrine was formulated in 1838-1839. I... |
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cena:
776,43 zł |
Biocomputing and biochemical studies of enzymes
ISBN: 9783639185904 / Angielski / Miękka / 204 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. The human kallikrein family is a family of proteolytic enzymes, classified as serine proteases, that derive from chromosome 19, locus 13.3-13.4. One member of the family, human kallikrein 4 (hK4) which is thought to carry out crucial functions in the prostate, was expressed in this study as a secreted protein in a baculovirus expression system, bearing a His-tag and V5-epitope that were used for purification and detection respectively. Computational analysis was included by applying high-performing computing techniques, such as molecular dynamics, and flexible ligand docking, to predict...
The human kallikrein family is a family of proteolytic enzymes, classified as serine proteases, that derive from chromosome 19, locus 13.3-13.4. One ...
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cena:
360,83 zł |
Transport Phenomena in Intervertebral Disc
ISBN: 9783639245042 / Angielski / Miękka / 216 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Low back pain represents a significant concern in the United States, with 70% of individuals experiencing symptoms at some point in their lifetime. Symptoms of low back pain have been strongly associated with degeneration of the intervertebral disc. Insufficient nutritional supply is believed to be a major mechanism for disc degeneration. Thus, understanding nutrients transport in intervertebral disc is crucial to elucidate the etiology of disc degeneration, and to develop strategies for tissue repair, and tissue engineering. Transport phenomena in intervertebral disc are still...
Low back pain represents a significant concern in the United States, with 70% of individuals experiencing symptoms at some point in their lifetime....
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cena:
378,87 zł |
A Theory of Calcium Dynamics in Paralyzed Human Soleus
ISBN: 9783639314601 / Angielski / Miękka / 348 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. In current models of muscle force and fatigue in denervated subjects, the mechanistic understanding of the role of baseline calcium current (R0) and the voltage sensitivity (km) is inadequate. R0 and km are assumed to be scalar, which generates errors in predicting force and fatigue respectively in response to external electrical stimulation. Previous work generated experimental data that conform to the Riccati/logistic/Boltzmann equation. To extend that work, a theoretical analysis of the role of calcium current, assumed to be a Riccati-Bass growth/diffusion/decay process, is presented for...
In current models of muscle force and fatigue in denervated subjects, the mechanistic understanding of the role of baseline calcium current (R0) and t...
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cena:
360,83 zł |
Liposomes Loaded with Topotecan and Vincristine for Cancer Treatment
ISBN: 9783639378504 / Angielski / Miękka / 136 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Remote loading of liposomes by transmembrane gradients is one of the best approaches for achieving the high drug level per liposome. This breakthrough, which enabled the clinical use of nanoliposomal drugs, has not been paralleled by good understanding that allows predicting loading efficiency of drugs. We developed a model that relates drug physicochemical properties and loading conditions to loading efficiency. This model enables choosing candidate molecules for remote loading and optimizing loading conditions according to logical considerations. In order to improve the therapeutic...
Remote loading of liposomes by transmembrane gradients is one of the best approaches for achieving the high drug level per liposome. This breakthro...
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cena:
269,48 zł |
Bayesian Methods in Structural Bioinformatics
ISBN: 9783642272240 / Angielski / Twarda / 386 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. This volume is a high-profile overview of the current state of play in statistical methods applied to structural bioinformatics. With almost 100 pages of introductory material, it covers topics including protein structure prediction and simulation.
This volume is a high-profile overview of the current state of play in statistical methods applied to structural bioinformatics. With almost 100 pages...
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cena:
388,20 zł |
Optical Coherence Tomography: A Clinical and Technical Update
ISBN: 9783642274091 / Angielski / Twarda / 255 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Optical Coherence Tomography represents the ultimate noninvasive ocular imaging technique although being in the field for over two-decades. This book encompasses both medical and technical developments and recent achievements. Here, the authors cover the field of application from the anterior to the posterior ocular segments (Part I) and present a comprehensive review on the development of OCT. Important developments towards clinical applications are covered in Part II, ranging from the adaptive optics to the integration on a slit-lamp, and passing through new structural and functional...
Optical Coherence Tomography represents the ultimate noninvasive ocular imaging technique although being in the field for over two-decades. This book ...
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cena:
388,20 zł |