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Store-Operated Ca2+ Entry (Soce) Pathways: Emerging Signaling Concepts in Human (Patho)Physiology
ISBN: 9783709109618 / Angielski / Twarda / 482 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. This book thoroughly explores robotics in neurorehabilitative therapy, describing state-of-the-art applications of robotic devices for locomotion; posture and balance and upper extremity recovery in stroke. Includes schematic diagrams, photographs and tables.
This book thoroughly explores robotics in neurorehabilitative therapy, describing state-of-the-art applications of robotic devices for locomotion; pos...
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cena:
580,98 zł |
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Contribution k aux effets biologiques des rayonnements ionisants
ISBN: 9786131510328 / Francuski / Miękka / 204 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Nous vivons dans un monde rayonnant, comportant radioactivitA(c) terrestre, rayonnements solaire, cosmique, et tous ceux que nous produisons. De faAon croissante les rayonnements X etc. sont utilisA(c)s dans l'imagerie mA(c)dicale ou comme outil de thA(c)rapie. Paradoxalement les mA(c)canismes radio-induits initiateurs de la mort cellulaire, de cancers, demeurent mA(c)connus. Face A l'A(c)mergence de tels cancers, comprendre les modes d'action d'un rayonnement ionisant sur l'ADN (cible privilA(c)giA(c)e des radiations) reprA(c)sente un enjeu majeur. La comprA(c)hension des processus physiques...
Nous vivons dans un monde rayonnant, comportant radioactivitA(c) terrestre, rayonnements solaire, cosmique, et tous ceux que nous produisons. De faAon...
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cena:
314,43 zł |
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Simulation Monte Carlo D Un Accélérateur Linéaire Médicale
ISBN: 9786131584046 / Francuski / Miękka / 132 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Ce travail vise, a evaluer la composante photoneutron produite au niveau de l'accelerateur lineaire medical du type VARIAN 2100C a differents points d'interet et pour differentes conditions d'irradiation. Dans la premiere etape du travail, nous avons modelise la tete de l'accelerateur a l'aide du code MCNP5 (Monte Carlo N-Particle) pour caracteriser les faisceaux de photons. Les parametres physiques et dosimetriques ont ete calcules et valides. L'etape suivante de notre travail, a consiste a calculer avec MCNP5, la composante photoneutrons produite par l'accelerateur a differents points...
Ce travail vise, a evaluer la composante photoneutron produite au niveau de l'accelerateur lineaire medical du type VARIAN 2100C a differents points d...
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cena:
254,74 zł |
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Effets d''une Cyclodextrine Au Sein de Systèmes Membranaires
ISBN: 9786131586927 / Francuski / Miękka / 88 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. La cellule et plus particuliA]rement les membranes qui la composent sont les piliers de la vie. Or, tout changement dans l''architecture molA(c)culaire de la membrane va irrA(c)mA(c)diablement entraA(R)ner une modification d''activitA(c) membranaire. C''est pourquoi cet ouvrage est une A(c)tude multispectroscopique mettant l''accent sur les modifications membranaires induites par voie alimentaire (rapport w3/w6) et plus spA(c)cifiquement mA(c)dicamenteuse, soit une cyclodextrine nommA(c)e Randomly-methylated beta-cyclodextrine (Rameb). La Diffusion Neutron aux petits angles est la premiA]re...
La cellule et plus particuliA]rement les membranes qui la composent sont les piliers de la vie. Or, tout changement dans l''architecture molA(c)culair...
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cena:
177,72 zł |
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Radiation Damage in Biomolecular Systems
ISBN: 9789400725638 / Angielski / Twarda / 510 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Since the discovery of X-rays and radioactivity, ionizing radiations have been widely applied in medicine both for diagnostic and therapeutic purposes. The risks associated with radiation exposure and handling led to the parallel development of the field of radiation protection. Since the discovery of X-rays and radioactivity, ionizing radiations have been widely applied in medicine both for diagnostic and therapeutic purpo... |
cena:
580,98 zł |
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Embryogenesis Explained
ISBN: 9789814350488 / Angielski / Twarda / 784 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. The greatest mystery of life is how a single fertilized egg develops into a fully functioning, sometimes conscious multicellular organism. Embryogenesis Explained offers a new theory of how embryos build themselves, and combines simple physics with the most recent biochemical and genetic breakthroughs, based on the authors' prediction and then discovery of differentiation waves. They explain their ideas in a form accessible to the lay person and a broad spectrum of scientists and engineers. The diverse subjects of development, genetics and evolution, and their physics, are brought together to...
The greatest mystery of life is how a single fertilized egg develops into a fully functioning, sometimes conscious multicellular organism. Embryogenes...
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cena:
1301,74 zł |
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Nature's Silent Music
ISBN: 9780911311334 / Angielski / Miękka / 246 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. In this book, scientist Philip Callahan shows how "civilized" insanity is turning Ireland away from her naturally harmonious, aesthetically pleasing, sound practices. Why remove a thatched roof to replace it with galvanized tin, only to increase the heating bill? With insightful wisdom, Callahan also examines the mysterious power of round towers, "magic spots," and healers such as Biddy Early. Callahan's study of hedgerows, booley people and Ireland's traditional form of agriculture can teach everyone the value of the land and why not to carelessly destroy it with toxic chemicals.
In this book, scientist Philip Callahan shows how "civilized" insanity is turning Ireland away from her naturally harmonious, aesthetically pleasing, ...
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cena:
96,66 zł |
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Band 3 Diffusion in Rbc and Implications for Rbc Membrane Structure
ISBN: 9783838353074 / Angielski / Miękka / 176 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Band 3 which is the one of the most abundant membrane protein in red blood cell membrane. It is bound to the spectrin network via other proteins such as ankyrin, 4.1 or junctional complex. In addition to that literature suggests the presence of different sub populations of band 3. The spectrin mesh leads to the hexagonal compartments in red blood cell membrane. The arrangement of this skeleton network affects the stability and the size of the compartments. We discovered that spectrin compartment size and the band3 diffusion vary from normal to disease patient's blood such as HbSS (Sickle cell...
Band 3 which is the one of the most abundant membrane protein in red blood cell membrane. It is bound to the spectrin network via other proteins such ...
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cena:
309,88 zł |
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The Role of Phycobilins in Cryptophyte Photosynthesis
ISBN: 9783838310121 / Angielski / Miękka / 232 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Understanding the detailed mechanisms of photosynthesis has become an ever increasingly important research field, as the community aims to apply the understandings from nature to design elements in organic photovoltaics. This thesis is a comprehensive study of the optical properties and the critical role of phycobiliproteins in the absorption of green light for photosynthesis in cryptophyte algae (Rhodomonas CS24 and Chroomonas CCMP270). Investigations of two different isolated proteins, phycoerythrin 545 and phycocyanin 645, are described in addition to investigating the workings of these...
Understanding the detailed mechanisms of photosynthesis has become an ever increasingly important research field, as the community aims to apply the u...
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cena:
360,00 zł |
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Folding Pathways of Photoactive Proton Pump Bacteriorhodopsin
ISBN: 9783838319438 / Angielski / Miękka / 152 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Stop-flow fluorescence and photodiode array spectroscopy, with a millisecond time resolution, are used here to investigate refolding kinetics of the photoactive proton pump bacteriorhodopsin in mixed DMPC/CHAPS micelles from a partially denatured state in SDS. The study suggests that both the apoprotein folding and subsequent binding of retinal chromophore likely proceed via distinct multiple parallel pathways to generate the native helical bundle. Taken together, these data should have profound implications on the mechanisms of folding of proteins within biological membranes.
Stop-flow fluorescence and photodiode array spectroscopy, with a millisecond time resolution, are used here to investigate refolding kinetics of the p...
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cena:
268,86 zł |
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Quantitative Determination of Labeled Cell Concentration Using MRI
ISBN: 9783838303390 / Angielski / Miękka / 112 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Focus of this study is to quantify the labeled cell con. using MRI. Two independent theories behind this relationship between MR parameters and labeled cell con. were proposed and tested in vitro and in vivo in rats after stroke. The first approach focused on the relationship between iron and labeled cell con. and R2p. R2p correlation with labeled cell con. is based on static dephasing regime theory. According to this theory, diffusion effects can be neglected if the protons do not migrate out of the local magnetic fields during a given echo time. R2p relaxivity agreed closely...
Focus of this study is to quantify the labeled cell con. using MRI. Two independent theories behind this relationship between MR parameters and labe...
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cena:
223,29 zł |
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Electrical Impedance Tomography
ISBN: 9783838340944 / Angielski / Miękka / 188 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Most EIT machines operate at high frequencies above 10 kHz. Biological systems demonstrate dispersions of electrical impedance characteristics at very low frequencies below 2 kHz due to the presence of membrane surrounding the cells and diffusion polarization effects. This book elaborate the feasibility of the use of low frequencies in a range of 1 Hz to 4.5 kHz in EIT. A frequency of 78 kHz normally used in EIT was used as a comparison. The impedance measurements employed a four-terminal method using an ultra low frequency impedance spectrometer and used conducting and insulating material as...
Most EIT machines operate at high frequencies above 10 kHz. Biological systems demonstrate dispersions of electrical impedance characteristics at very...
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cena:
309,88 zł |
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Beneficial Noise and Perilous Oscillations in the Nervous System
ISBN: 9783838342276 / Angielski / Miękka / 104 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Computational modeling of cooperative dynamics in excitable systems is important for uncovering mechanisms that underlie perturbation propagation in the nervous system. In this dissertation, two spatially extended networks of FitzHugh-Nagumo neurons operating in the subexcitable and hyperexcitable regime are studied by computational methods, leading to two key conclusions. First, the length and speed of perturbation propagation in the subexcitable FitzHugh-Nagumo system is maximized by spatiotemporal noise of optimal intensity. This indicates that random fluctuations in neuronal excitability...
Computational modeling of cooperative dynamics in excitable systems is important for uncovering mechanisms that underlie perturbation propagation in t...
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cena:
223,29 zł |
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Instrumentation for Lesion Detection
ISBN: 9783838321929 / Angielski / Miękka / 180 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. To image small lesions within the body requires instrumentation that has very high resolution, has high sensitivity, and can suppress large background signals. This can be achieved with beta-emitting radioactive tracers. To detect these tracers, the detection device must be small, compact, and placed in close proximity to the lesions, virtually touching them. This book presents design concepts, as well as the building and evaluation of such devices, for imaging vulnerable plaques and residual cancer cells. Detailed disease descriptions, as well as comprehensive references, are also presented....
To image small lesions within the body requires instrumentation that has very high resolution, has high sensitivity, and can suppress large background...
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cena:
309,88 zł |
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Photosynthesis -
ISBN: 9783838346106 / Angielski / Miękka / 128 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. An analysis of the consequences arising from the non- linearity of the photosynthetic light curves on the values of quantum requirement, as well as on the action spectra and quantum efficiency spectra in dependence of the suspension optical densities is presented. A kinetic model of the oxygen production reaction is elaborated in which in addition to the non-cooperative (Koks)mechanisms a cooperative one is also included. According to this model the oxygen precursors obtained in different oxygen evolving reaction centres could migrate in the surrounding media and recombine. The two...
An analysis of the consequences arising from the non- linearity of the photosynthetic light curves on the values of quantum requirement, as well as o...
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cena:
268,86 zł |
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Mechanism of Kinesin Motility
ISBN: 9783838354187 / Angielski / Miękka / 68 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Motor proteins are enzymes that are responsible for molecular transport. Those proteins convert the chemical energy derived from the hydrolysis of ATP directly into mechanical work and are necessary for the eukaryotic cell to achieve complex organizational and structural tasks. Motor proteins allow efficient transport of molecular structures and organelles such as vesicles, mitochondria, and chromosomes which is necessary since diffusion is too slow to efficiently move material from one part of the cell to another on physiological time scales [1]. This ability to control cellular transport...
Motor proteins are enzymes that are responsible for molecular transport. Those proteins convert the chemical energy derived from the hydrolysis of ATP...
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cena:
223,29 zł |
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Imaging of Creatine Deposits in Human CNS Tissues
ISBN: 9783838384832 / Angielski / Miękka / 132 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Synchrotron infrared spectromicroscopy and X-Ray Fluorescence spectromicroscopy have been applied to imagine human central nervous system tissue. Untreated, flash frozen tissue samples were analyzed at micron level spatial resolution to obtain information about chemical composition of the sample. Bright synchrotron light allowed the high spatial resolution (8-10 microns) needed for this study. In the family of neurodegenerative diseases, Amyotrophic Lateral Sclerosis (ALS) is the most frequent cause of adult onset. ALS symptoms include: generalized weakness and muscle atrophy. The...
Synchrotron infrared spectromicroscopy and X-Ray Fluorescence spectromicroscopy have been applied to imagine human central nervous system tissue. U...
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cena:
268,86 zł |
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Modelling biological systems
ISBN: 9783843353571 / Angielski / Miękka / 116 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Networks of coupled oscillators are observed in various domains of science. From physics to economy through biology, they are used to explain how collective behaviour emerges from interacting oscillators. In this book, we study through two specific examples, how biological systems use the distinctive properties of interconnected networks, widely studied in the biophysical science, to propagate informations and regulate vital physiological processes. Our interest focuses on: (1) Extension of the study of the communication via Ca2+ waves to a 1D and a 2D array of cells. (2) Communication...
Networks of coupled oscillators are observed in various domains of science. From physics to economy through biology, they are used to explain how coll...
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cena:
223,29 zł |
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Molecular Regulation of the Exocytic Mode in Adrenal Chromaffin Cells
ISBN: 9783843359191 / Angielski / Miękka / 292 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Neuroendocrine chromaffin cells of the adrenal medulla are a primary output for the sympathetic nervous system. Chromaffin cells release catecholamine as well as vaso- and neuro-active peptide transmitters into the circulation through exocytic fusion of large dense-core secretory granules. Under basal sympathetic firing, chromaffin cells selectively release modest levels of catecholamines, helping to set the "rest and digest" status of energy storage. Under stress activation, elevated sympathetic firing leads to increased catecholamine as well as peptide transmitter release to set the "fight...
Neuroendocrine chromaffin cells of the adrenal medulla are a primary output for the sympathetic nervous system. Chromaffin cells release catecholamine...
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cena:
378,00 zł |
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Impact of Load Carriage on Gait and Muscle Activity
ISBN: 9783838381848 / Angielski / Miękka / 308 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. The amount of loads carried in backpacks by school children has been increasing over the last two decades raising concerns among medical practitioners and parents about the possible detrimental effects prolonged heavy load carriage can have on the musculoskeletal system. Previous studies have indicated that loads higher than 15% of body weight affect the gait and trunk posture of children and can cause long term musculoskeletal problems. It has been reported in many countries that due to the structure of the curriculum, children usually carry loads as high as 22-25% of their body weight....
The amount of loads carried in backpacks by school children has been increasing over the last two decades raising concerns among medical practitioners...
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cena:
378,00 zł |
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