In current models of muscle force and fatigue in denervated subjects, the mechanistic understanding of the role of baseline calcium current (R0) and the voltage sensitivity (km) is inadequate. R0 and km are assumed to be scalar, which generates errors in predicting force and fatigue respectively in response to external electrical stimulation. Previous work generated experimental data that conform to the Riccati/logistic/Boltzmann equation. To extend that work, a theoretical analysis of the role of calcium current, assumed to be a Riccati-Bass growth/diffusion/decay process, is presented for...
In current models of muscle force and fatigue in denervated subjects, the mechanistic understanding of the role of baseline calcium current (R0) and t...