Kategoria BISAC: Science >> Life Sciences - Biology

• Includes numerous, timely, state-of-the-art reviews
• Features distinguished, well recognized authors from around the world
• Builds upon this venerable and iconic review series
• Covers the extensive...

Nonsense Mutation Correction in Human Diseases: An Approach for Targeted Medicine provides an introduction on genetic diseases, discusses the prevalence of nonsense mutations, the consequences of a nonsense mutation for the expression of the mutant gene, and the presentation of the nonsense-mediated mRNA decay (NMD).

It presents the mechanism of action and rationale associated with each strategy to correct nonsense mutations with the results of clinical trials to further support this basis. In addition, the book shows how it may be possible to combine several of these...

Friends and Partners: The Legacy of Franklin D. Roosevelt and Basil O'Connor in the History of Polio presents the story of two men, one the President of the United States, the other an ambitious attorney, who became the "architects of the fight against polio." With unfettered access to the March of Dimes Archives, this book explores the friendship and partnership that ensured the end of polio in the US, with exclusive pictures and documentation.

The book describes the founding and history of Franklin D. Roosevelt's (FDR) polio colony in Warm Springs, Georgia, and the early...

Advanced Mechanical Models of DNA Elasticity includes coverage on 17 different DNA models and the role of elasticity in biological functions with extensive references. The novel advanced helicoidal model described reflects the direct connection between the molecule helix structure and its specific properties, including nonlinear features and transitions. It provides an introduction to the state of the field of DNA mechanics, known and widely used models with their short analysis, as well as coverage on experimental methods and data, the influence of electrical, magnetic, ionic...

Imaging in Dermatology covers a large number of topics in dermatological imaging, the use of lasers in dermatology studies, and the implications of using these technologies in research. Written by the experts working in these exciting fields, the book explicitly addresses not only current applications of nanotechnology, but also discusses future trends of these ever-growing and rapidly changing fields, providing clinicians and researchers with a clear understanding of the advantages and challenges of laser and imaging technologies in skin medicine today, along with the cellular and...

Diagnostic Molecular Pathology: A Guide to Applied Molecular Testing is organized around disease types (genetic disease, infectious disease, neoplastic disease, among others). In each section, the authors provide background on disease mechanisms and describe how laboratory testing is built on knowledge of these mechanisms. Sections are dedicated to general methodologies employed in testing (to convey the concepts reflected in the methods), and specific description of how these methods can be applied and are applied to specific diseases are described.

The book does not...

Basic Science Methods for Clinical Researchers addresses the specific challenges faced by clinicians without a conventional science background. The aim of the book is to introduce the reader to core experimental methods commonly used to answer questions in basic science research and to outline their relative strengths and limitations in generating conclusive data.

This book will be a vital companion for clinicians undertaking laboratory-based science. It will support clinicians in the pursuit of their academic interests and in making an original contribution to their chosen...

Surgical Treatment of Atrial Fibrillation: A Comprehensive Guide to Performing the Cox-Maze IV Procedure is the first all-inclusive description of this rapidly growing surgery, setting the standard in the field. The Cox-Maze IV procedure is a complex surgery, and its success depends critically on correct execution. With FDA approval, the first RF ablation device for treatment of the Cox-Maze IV procedure has become more important than ever to combine scientific information for the procedure with its connection to human application.

This comprehensive text provides...

Few people realize how much science can tell us about the differences between men and women. Yves Christen, provided the first comprehensive overview of research in this area when this classic book was first published in the1990s. He goes beyond simplistic "biology is destiny" arguments and constructs a convincing case for linking social and biological approaches in order to understand complex differences in behaviour.

Biologists agree that the sexes differ in brain and body structure. Christen links these differences in cerebral anatomy to differences in behaviour and intellect....

Advances in sequencing technology have allowed scientists to study the human genome in greater depth and on a larger scale than ever before - as many as hundreds of millions of short reads in the course of a few days. But what are the best ways to deal with this flood of data?

Algorithms for Next-Generation Sequencing is an invaluable tool for students and researchers in bioinformatics and computational biology, biologists seeking to process and manage the data generated by next-generation sequencing, and as a textbook or a self-study resource. In addition to offering an...