Epigenetic Methods in Neuroscience Research
ISBN: 9781493927531 / Angielski / Twarda / 258 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. This volume presents state-of-the-art methods for reliable detection of epigenetic changes in the nervous system.Epigenetic Methods in Neuroscience Research guides readers through methods for the analyses of chromatin remodeling, transposable elements, non-coding RNAs, such as miRNAs, and circadian oscillations, including: analysis of DNA methylation in neuronal and glial cells or small tissue samples; sensitive method for quantification of alternative methylated forms of cytosines by liquid chromatography/mass spectrometry; affinity-based detection of modified cytosines by... This volume presents state-of-the-art methods for reliable detection of epigenetic changes in the nervous system.Epigenetic Methods in Neuroscie... |
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389,98 zł |
The $1,000 Genome
ISBN: 9781416569619 / Angielski / Miękka / 352 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Since the conclusion of the Human Genome Project in 2003, scientists have been racing towards a grand goal: offering individuals a decoding of their complete genetic makeup for just $1,000. As Kevin Davies reveals in this exquisitely reported account, the $1,000 genome will be a reality by 2011 and it will usher in a whole new era of personalized, genomic medicine. Capable of presenting much more advanced information than the current crop of cheek-swab services, the $1,000 complete genome raises some extraordinary possibilities. We will be able to learn if we have genes that predispose us to...
Since the conclusion of the Human Genome Project in 2003, scientists have been racing towards a grand goal: offering individuals a decoding of their c...
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77,11 zł |
Post-Genomic Approaches in Drug and Vaccine Development
ISBN: 9788793102842 / Angielski / Twarda / 452 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Over the past decade, genome sequencing projects and associated efforts have facilitated the discovery of several novel disease targets and the approval of several innovative drugs. To further exploit this data for human health and disease, there is a need to understand the genome data itself in detail, discover novel targets, and understand their role in physiological pathways and associated diseases with the aim of translating these discoveries to clinical and preventive medicine. It is equally important to understand the labors and limitations in integrating clinical phenotypes with...
Over the past decade, genome sequencing projects and associated efforts have facilitated the discovery of several novel disease targets and the approv...
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433,21 zł |
The Male Role in Pregnancy Loss and Embryo Implantation Failure
ISBN: 9783319188805 / Angielski / Twarda / 228 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Novel topics compiled in this one-of-a-kind volume provide tantalizing hints for clinical application through future translational research. Only recently have we come to ask what role the male might play in pregnancy loss and embryo implantation failure, beyond contributing an abnormal set of paternal chromosomes at fertilization. This volume explores the recent evidence that these conditions might also be related to the transmission of previously unrecognized chromosomal micro-deletions and duplications, or via the epigenetic dysregulation of early embryonic gene function by spermatozoal...
Novel topics compiled in this one-of-a-kind volume provide tantalizing hints for clinical application through future translational research. Only rece...
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389,98 zł |
Gene Therapy and Cell Therapy Through the Liver: Current Aspects and Future Prospects
ISBN: 9784431556657 / Angielski / Twarda / 185 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. This book reports the recent progress in gene and cell therapy through the liver and aims to facilitate a comprehensive understanding of the current aspects and future prospects from basic research to clinical therapies. Edited by pioneering researchers, this volume presents extensive information to principal investigators, researchers, postdocs and clinicians for examining the wide varieties of pathological conditions both inside and outside the liver. Providing not only the basic and clinical aspects of therapy, this volume is special in that it focuses on the administrative and...This book reports the recent progress in gene and cell therapy through the liver and aims to facilitate a comprehensive understanding of the curren... |
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389,98 zł |
Human Genetic Biobanks in Asia: Politics of trust and scientific advancement
ISBN: 9780415541411 / Angielski / Miękka / 224 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. This volume investigates human genetic biobanking and its regulation in various Asian countries and areas, including Japan, Mainland China, Taiwan, Hong Kong, India and Indonesia. It sheds light on how cultural, socio-political and economic factors influence the set-up of bioethical regulation for human genetic biobanks and how bioethical sensitivities surrounding biobanks are handled. Apart from placing discourses of trust in an international perspective, the comparative materials presented in this volume also put into perspective the concepts of genetic theft and exploitation, and genetic...
This volume investigates human genetic biobanking and its regulation in various Asian countries and areas, including Japan, Mainland China, Taiwan, Ho...
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152,87 zł |
Selected Genetic Papers of J.B.S. Haldane (Routledge Revivals)
ISBN: 9781138783430 / Angielski / Miękka / 543 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. First published in 1990, this is a compilation of several important papers that have contributed to the foundation of population genetics, evolutionary biology and human genetics. The collection includes Haldane s first paper in genetics, which was published in 1915, reporting the first case of linkage in a mammal, and - fifty years later, in 1965 - his last paper in genetics on selection for a single pair of allelomorphs with complete replacement. Haldane's Rule, the only idea named after him, was published in 1922 and is still valid today. Other papers, which include many Haldane firsts,... First published in 1990, this is a compilation of several important papers that have contributed to the foundation of population genetics, evolutio... |
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249,71 zł |
Gene-Environment Interplay in Interpersonal Relationships Across the Lifespan
ISBN: 9781493929221 / Angielski / Twarda / 281 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Intriguing new findings on how genes and environments work together through different stages of life take the spotlight in this significant collection. Studies from infancy to late adulthood show both forces as shaping individuals' relationships within family and non-family contexts, and examine how these relationships, in turn, continue to shape the individual. Transitional periods, in which individuals become more autonomous and relationships and personal identities become more complicated, receive special emphasis. In addition, chapters shed light on the extent to which the quantity and... Intriguing new findings on how genes and environments work together through different stages of life take the spotlight in this significant collect... |
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194,97 zł |
Chromosomal Instability in Cancer Cells
ISBN: 9783319202907 / Angielski / Twarda / 224 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. This issue of Recent Results in Cancer Research presents a comprehensive review of current understanding of chromosomal instability in cancer and of strategies to use this information for better treatment of patients with cancer.
This issue of Recent Results in Cancer Research presents a comprehensive review of current understanding of chromosomal instability in cancer and of s...
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194,97 zł |
Prenatal and Postnatal Determinants of Development
ISBN: 9781493930135 / Angielski / Twarda / 364 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. This volume provides readers with an introduction to all the methods and major approaches now being used to study the structural and functional development of the brain. Prenatal and Postnatal Determinants of Development explores early anatomical development, the emergence of function and the processes that lead to damage and repair of the growing and immature brain.Chapters are divided into three sections covering development, programming and stress, and brain damage-causes and consequences. Written in the popular Neuromethods series style, chapters include the kind of detail...
This volume provides readers with an introduction to all the methods and major approaches now being used to study the structural and functional develo...
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389,98 zł |
Medical and Health Genomics
ISBN: 9780124201965 / Angielski / Twarda / 358 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Medical and Health Genomics provides concise and evidence-based technical and practical information on the applied and translational aspects of genome sciences and the technologies related to non-clinical medicine and public health. Coverage is based on evolving paradigms of genomic medicine--in particular, the relation to public and population health genomics now being rapidly incorporated in health management and administration, with further implications for clinical population and disease management.
Medical and Health Genomics provides concise and evidence-based technical and practical information on the applied and translational aspects... |
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519,92 zł |
Microarray Data Analysis: Methods and Applications
ISBN: 9781493931729 / Angielski / Twarda / 226 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. This volume covers a large area, from the description of methodologies for data analysis to the real application. Chapters focus on methodologies for preprocessing of microarray data, a survey of miRNA Data analysis, Cloud-based approaches, application of data mining techniques for data analysis, biclustering to query different datasets, web-based tool to analyze the evolution of miRNA clusters, application of biclustering to mine patterns of co-regulated genes ontologies, microarray and proteomic Data, Gene Regulatory Network Inference, Gene Regulatory Network methods, analysis of Mouse... This volume covers a large area, from the description of methodologies for data analysis to the real application. Chapters focus on methodologies f... |
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389,98 zł |
Cancer Gene Profiling: Methods and Protocols
ISBN: 9781493932030 / Angielski / Twarda / 256 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. This second edition volume brings together the experiences of leading scientists in the discipline of cancer gene profiling. Because cancer genes can be profiled in many different ways, Cancer Gene Profiling: Methods and Protocols, Second Edition explores different techniques and approaches needed to understand the key stages of cancer development, as using only one technique would be insufficient. This book provides readers with an overview of the state-of-the-art methods that will enable them to perform these experiments, and demonstrates the kind of analysis that is possible in... This second edition volume brings together the experiences of leading scientists in the discipline of cancer gene profiling. Because cancer genes c... |
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389,98 zł |
Gene Therapy for Neurological Disorders: Methods and Protocols
ISBN: 9781493932702 / Angielski / Twarda / 493 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. This volume provides a clear and detailed roadmap of how to design and execute a gene therapy experiment in order to obtain consistent results. Chapters in this book disseminate bits of unknown information that are important to consider during the course of experimentation and will answer questions such as: What delivery vehicle do you use?; How will you ensure that your vector retains stability?; What expression system best fits your needs?; What route will you choose to deliver your gene therapy agent?; How will you model the neurodegenerative disorder that you aim to investigate and... This volume provides a clear and detailed roadmap of how to design and execute a gene therapy experiment in order to obtain consistent results. Cha... |
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585,00 zł |
RNA Imaging: Methods and Protocols
ISBN: 9781493931477 / Angielski / Twarda / 218 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. This detailed volume will focus on the phenomenon of RNA interference by providing comprehensive coverage of various techniques for in vivo micro/siRNA imaging including the design and synthesis of specific imaging agents and tools, the development of imaging methodologies, and their interpretation. An essential element in the development and optimization of these therapies is the ability to measure the bioavailability and functionality of the RNA/oligonucleotide molecule after administration into the body. Noninvasive imaging provides the necessary set of tools to accomplish this in... This detailed volume will focus on the phenomenon of RNA interference by providing comprehensive coverage of various techniques for in vivo micro/s... |
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389,98 zł |
Pten: Methods and Protocols
ISBN: 9781493932979 / Angielski / Twarda / 324 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. This volume provides detailed descriptions of prevailing and novel techniques used by experts in the study of PTEN function in disease and biology. The book begins with chapters exploring methods to detect expression levels of PTEN in normal and diseased human specimens; methods to evaluate specific PTEN function in brain cancer; methods that utilize a new biosensor to measure PTEN regulation; and techniques to measure post-transcriptional regulation of PTEN by micoRNAs and ceRNAs. Other chapters present methods describing novel techniques to detect PTEN localization and previously... This volume provides detailed descriptions of prevailing and novel techniques used by experts in the study of PTEN function in disease and biology.... |
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389,98 zł |
Novel Biomarkers in the Continuum of Breast Cancer
ISBN: 9783319229089 / Angielski / Twarda / 279 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. This volume provides a comprehensive review of established and novel biomarkers across the continuum of breast cancer. The volume covers topics related to breast cancer risk and prevention, prediction of response to today s standard therapies, and markers capable of influencing treatment decisions in the near future. Chapter authors combine their wide-ranging expertise to review the current status of the biomarker and to offer their individual perspectives on how biomarkers may be used in future treatments and research.Breast cancer continues to be the most common malignancy diagnosed...
This volume provides a comprehensive review of established and novel biomarkers across the continuum of breast cancer. The volume covers topics relate...
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389,98 zł |
Deciphering the Mechanism of Immune Dysfunction in Vici Syndrome
ISBN: 9783656945963 / Angielski / Miękka / 100 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Doctoral Thesis / Dissertation from the year 2015 in the subject Medicine - Human Genetics, grade: 1, University of Rome -La Sapienza- (University of Rome -La Sapienza-), course: Clinical Immunology, language: English, abstract: Vici syndrome is a complex multisystem disorder characterized by congenital malformations of the brain, cataracts, skin hypopigmentation, progressive damage of cardiac function and muscle, immune deficiency. Affected children do not respond to vaccination, have low levels of antibodies in the blood and suffering from severe and frequent infections. The disease is...
Doctoral Thesis / Dissertation from the year 2015 in the subject Medicine - Human Genetics, grade: 1, University of Rome -La Sapienza- (University of ...
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296,44 zł |
Epigenetic Advancements in Cancer
ISBN: 9783319249490 / Angielski / Twarda / 246 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. |
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389,98 zł |
Healing One Cell At a Time: Unlock Your Genetic Imprint to Prevent Disease and Live Healthy
ISBN: 9780692512272 / Angielski / Miękka / 162 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Before Gordon Crozier was "Doctor" Gordon Crozier, he was chronically ill. He was so sick he couldn't crawl off the bed, so ill he could hardly eat, so cognitively impaired that for two years he lost the ability to read. He was desperate and his doctors literally gave up. But there was a silver lining in his sickness; it led him to find answers in the study of integrative medicine and how a person's genetic make-up can ultimately bring healing. Dr. Crozier's own sickness became a pathway to healing for others. In this groundbreaking book, you'll discover how Dr. Gordon... Before Gordon Crozier was "Doctor" Gordon Crozier, he was chronically ill. He was so sick he couldn't crawl off the bed, so ill he could hardly eat... |
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68,50 zł |