This text presents a comprehensive mathematical theory for elliptic, parabolic, and hyperbolic differential equations. It compares finite element and finite difference methods and illustrates applications of generalized difference methods to elastic bodies, electromagnetic fields, underground water pollution, and coupled sound-heat flows.

Thisbookisacollectionof31paperspresentedattheInternationalWorkshop on Modern Trends in Geomechanics, held on 27 29 June 2005 in Vienna. This workshop was run under the motto to bring together di?erent schools of thought in geomechanics research. The workshop was attended by about 50 participants from 15 countries. Besides the presentations, the workshop also o?ered welcoming occasions for stimulating discussions. The contributions in this book cover a wide range of topics from applied mathematics to geoengineering applications, re?ecting the breadth and depth of geomechanics research. The...

The tiny microRNAs (miRNAs) can have huge impacts on the regulation of a variety of genes and play crucial roles in the fundamental cellular processes. Recent miRNA studies change the landscape of cancer genetics by scrutinizing the alterations of genome-wide miRNA expressions in most common cancers and their regulatory functions during the development of cancer. The connections between miRNAs and cancer are widespread enough to warrant more comprehensive investigations in the systems biology perspective. In MicroRNA and Cancer: Methods and Protocols, internationally renowned experts provide...

Thisbookisacollectionof31paperspresentedattheInternationalWorkshop on Modern Trends in Geomechanics, held on 27-29 June 2005 in Vienna. This workshop was run under the motto to bring together di?erent schools of thought in geomechanics research. The workshop was attended by about 50 participants from 15 countries. Besides the presentations, the workshop also o?ered welcoming occasions for stimulating discussions. The contributions in this book cover a wide range of topics from applied mathematics to geoengineering applications, re?ecting the breadth and depth of geomechanics research. The...

Providing quality public service is one of the essential functions of a government. In the turbulent time, however, governments worldwide are experiencing a variety of unprecedented challenges to meet citizens' increasing demands and expectations. In China, building a service-oriented government and a harmonious society is central to the 12th Five-Year Plan and challenges the governance philosophies, capacities and competencies of Chinese government at every level. Researchers of Nanyang Centre for Public Administration (NCPA) at Nanyang Technological University systematically examined the...

This volume providesan interdisciplinary perspective ofapplying Next Generation Sequencing (NGS) technology to cancer research. It aimsto systematically introduce the concept of NGS, a variety of NGS platforms and their practical implications in cancer biology.This unique and comprehensive textwill integrate the unprecedented NGS technology into various cancerresearch projectsas opposed to most books which offera detaileddescription of the technology. This volume willpresent true experimental results with concrete data processing pipelines, discuss the bottleneck of each platform for real...

Latest generation sequencing revolutionizes the fields of cancer research and oncology. This follow-up volume focuses more extensively on single cell sequencing of cancer and trials in drug resistance. Another exciting feature is the bioinformatics tools given, that can be used on cancer genome studies. Scientists around the world are attempting to find the root cause of cancer. A reasonable cancer treatment plan and potential cure is more optimistic now with the unfolding of the cancer genome. The collective knowledge of how to leverage next generation sequencing in cancer research is paving...

Latest generation sequencing revolutionizes the fields ofcancer research and oncology.This follow-up volume focuses more extensivelyonsingle cell sequencing ofcancer and trials in drug resistance. Anotherexciting featureis thebioinformatics tools given, that can be used oncancer genomestudies.Scientists around the world are attempting to find the root cause of cancer. A reasonablecancer treatment plan and potential cure is more optimistic now with the unfolding of the cancer genome. Thecollective knowledge of howto leverage next generation sequencing in cancer research is paving the way.The...