Kategoria BISAC: Medical >> Pulmonary & Thoracic Medicine

Exploring new pathways for the development of pharmacological agents and methods for disease intervention, this source includes chapters on genetic epidemiology, techniques in statistical analysis, and the use of animal models for the study of airway disease genetics presents the results of recent linkage and association studies and epigenetic and environmental influences, and considers their impact on the future management of asthma and COPD considers the development of proteomic strategies to possibly detect relevant proteins in disease development and progression weighs the possibility...

Inflammatory Cells and Mediators in Bronchial Asthma provides reviews and summaries regarding state-of-the-art articles that examine the role of various inflammatory cells and their mediators in the pathogenesis of asthma. Topics include pharmacological and biochemical regulation of the airways; involvement of key inflammatory cells and the release and effect of their mediators in airway function; and the characteristics of receptors for leukotriene B4, C4, and D4, adenosine, platelet-activating factor, sensory and inflammatory peptides, and the effect of various anti-asthmatic drugs on...

This title presents a comprehensive review of the most recent strategies used to assess, treat and manage patients in each phase of chronic obstructive pulmonary disease (COPD).

As our population continues to grow, more and more patients are becoming dependent on long-term ventilatory support. Therefore, the need for quality options such as home mechanical ventilation is fast becoming a necessity. Ventilatory Support For Chronic Respiratory Failure (CRF) is the first resource to authoritatively address the needs of the acute or chronic respiratory patient through the transition from the hospital to the home-care setting.

This reference covers best practices in the management of CRF patients who are:

• clinically...

This book, commissioned by the World Health Organization (WHO) and written by international experts, provides consensus views on the most important issues related to allergic hypersensitivities. The text details predictive testing, diagnosis, epidemiological monitoring of intervention measures, sources of sensitizing agents, and mechanisms of action.
Contributors extensively cover allergic hypersensitivity reactions of the skin and the respiratory system. They present the current knowledge on hypersensitivity reactions of the gastrointestinal tract and kidneys. Major gaps in existing...

Practical Immunology is a basic text aimed at immunology students and researchers at all levels who need a comprehensive overview of the methodology of immunology. The rapid and startling innovations in immunology over the past two decades have their root in sound experimental practice and it has always been the aim of this book to educate researchers in the design and performance of complex techniques. It will appeal to students of immunlogy, graduate students embarking on bench science, or specialised immunologists who need to use an immunological technique outside their sphere of...

Asthma has rapidly become one of the most common chronic illnesses of the Western world, and its prevalence continues to rise, with the proportion of patients with more severe diseases also increasing. Faced with this problem, more researchers are focusing on the causes, mechanisms, and pathophysiology of asthma. The major hopes are that more effective drugs will become available and that preventive measures can be instituted. Increasingly, molecular and cell bi- ogy approaches are being used to characterize and understand the mechanisms of the inflammatory process that is typical of the...

Carole Mendelson has assembled a panel of leading investigators to critically review the various classes of endocrine, paracrine, and neuroendocrine factors that play a role in the regulation of lung development and surfactant production. Special attention is accorded the actions of glucocorticoids in lung development and the synthesis of surfactant glycerophospholipids and proteins. Also extensively treated are the roles of cell-cell interactions and the elaboration of various growth factors and bioactive peptides in pulmonary cell differentiation, gene expression, and pathophysiology....

Rubor (redness), tumor (swelling), calor (heat), and dolor (pain) are the classical signs of inflammation. These features are obvious in the skin, where injury or disease causes flare, wheal, and painful burning sensations. Vasodi- tation underlies the flare and heat, plasma exudation the swelling, and acti- tion of sensory nerves relays pain. In chronic conditions, skin biopsies show inflammatory cell infiltrate. Inflammation is not unique to the skin and contr- utes to disease and repair processes in other organ systems in the body. From the viewpoint of this volume, lung inflammation is...

XIII List of contributors A. Experimental studies A simple mathematical model of High Frequency Ventilation. 1 A. Versprille. Development and clinical application of High Frequency Ventilation. 12 U.H. Sjostrand- L. Bunegin, R.B. Smith, i.F. Babinski. Convective diffusion in oscillatory flow as a gas transport 39 mechanism during High Frequency Ventilation. H.J. van Ouwerkerk, P. Gieles, J.M. Bogaard. Pressure flow pattern and gas transport using various types of 51 High Frequency Ventilation. M. Baum, H. Benzer, W. Goldschmied, N. Mutz. A review of experimental and theoretical studies of...

Complete reference on hypoxic pulmonary vasoconstriction and hypoxia-mediated pulmonary hypertension.

Can be utilized by the physician-scientist and researcher in the laboratory as both a technical manual and reference.

Designed for clinicians to guide and improve clinical treatment and diagnosis of patients with hypoxia mediated pulmonary vascular disease and right heart failure.

The only international clinical textbook for COPD - one of the top 5 causes of death and disability worldwide

• The only COPD textbook to include the latest national and international guidelines and the newer therapeutic agents in COPD treatment
  
  
• International team of contributors covers all aspects of COPD - from physiology and epidemiology to diagnosis and treatment
  
  
• Everything the busy physician needs to understand, diagnose and treat the COPD patient:

  - Structure and physiology of the respiratory system
  ...

Removing the guesswork associated with Interstitial Lung Disorders (ILDs) and bronchiolar disorders, Interstitial Pulmonary and Bronchiolar Disorders addresses the issues faced by pulmonologists in treating these disorders. Divided into sections based on the disease type (granulomatous, pneumonias, bronchiolar disorders, vasculitis, and orphan lung disease), each disorder is covered from epidemiological, pathogenic, clinical, and radiographic perspectives.

The only text on the market today that deals with the entire spectrum of ILDs, this handy,...

Maintaining the first edition s unique parallel to the strategy used by pathologists and pulmonologists to arrive at a patient s diagnosis in daily practice, Diagnostic Pulmonary Pathology starts with the patient and their biopsy findings, directing the pathologist or clinician to the proper diagnosis. With many advances in pulmonary pathology, radiology, and pulmonary medicine, this new edition provides thorough updates in:

• progress in classification and diagnosis of interstitial lung diseases
• evolution of our understanding of...

Written as a concise clinical reference guide covering the current and future airway disease treatments, this text encompasses:

• pathophysiology of respiratory tract diseases
• the methods of measuring airway and clinical responses
• the concepts upon which many treatments are used in COPD and asthma conditions
• the way in which these treatments work, and how new treatments can be discovered and tested in various patient groups
• state-of-the-art pharmacological and therapeutic approaches in controlling pathophysiological processes in the...

Chronic Obstructive Pulmonary Disease Exacerbations covers the definition, diagnosis, epidemiology, mechanisms, and treatment associated with COPD exacerbations. This text also addresses imaging and how it plays a pivotal role in the diagnosis and study of exacerbations.

Written by today's top experts, Chronic Obstructive Pulmonary Disease Exacerbations:

• is formatted into separate sections covering imaging diagnosis and treatment, making this text practical and easy-to-use
...

Written by an expanded team of leading international scientists, the second edition thoroughly investigates research and therapies for managing adverse physiological effects of air-borne particles on the respiratory tract. The book examines the lung as the gateway for particle damage to organs outside the respiratory system and provide the information needed to understand and combat the numerous and varied ailments caused by inhaled particles.

This authoritative reference reviews current and emerging molecular imaging modalities that are expected to impact the detection and treatment of lung diseases in the near future-including applications in gene expression and inflammation imaging; the imaging of pulmonary cytokine regulation; the molecular imaging of angiogenesis, the airways, and lung cancer; and the imaging of cellular death and cell trafficking.

Providing a solid foundation for specialists in asthma treatment and control, this guide illustrates the importance of asthma monitoring practices for up-to-date assessments of disease levels in specific population groups; the identification of social, geographical, and environmental factors that may influence the development of asthma; and the design of improved and cost-effective prevention and management strategies for optimal patient care.

Lung Pathology: A Consultative Atlas and its companion CD complement each other as a novel and substantive approach to teaching the complex elements of pulmonary pathology. They exhibit challenging yet exemplary cases of lung pathology to help the reader understand diagnostic elements of morphology and to work his or her way through tables of differential diagnoses. These cases have been drawn from a 20-yr file of more than 7000 referrals to Dr. Eugene Mark from pathologists throughout the world. This volume introduces the reader to an updated approach developed by Dr. Mark in the...