This volume presents a global overview of the role of ion flux via transmembrane ion channel proteins in the regulation of pulmonary vascular tone and in the vascular remodeling processes associated with pulmonary vascular disease-offering a comprehensive review of the multiple families of ion channels that have been identified and characterized in pulmonary artery smooth muscle, as well as a practical discussion of experimental tools for the study of ion channel physiology and molecular biology.

Complete reference on hypoxic pulmonary vasoconstriction and hypoxia-mediated pulmonary hypertension.

Can be utilized by the physician-scientist and researcher in the laboratory as both a technical manual and reference.

Designed for clinicians to guide and improve clinical treatment and diagnosis of patients with hypoxia mediated pulmonary vascular disease and right heart failure.

Membrane Receptors, Channels and Transporters in Pulmonary Circulation is a proceeding of the 2008 Grover Conference (Lost Valley Ranch and Conference Center, Sedalia, Colorado; September 3-7, 2008), which provided a forum for experts in the fields of those receptors, channels and transporters that have been identified as playing key roles in the physiology and pathophysiology of the pulmonary circulation. The book rigorously addresses: i) recent advances in our knowledge of receptors, channels and transporters and their role in regulation of pulmonary vascular function; ii) how modulation of...