Particle-Lung Interactions

ISBN-13: 9781420072563 / Angielski / Twarda / 2009 / 344 str.

Peter Gehr; Fabian Blank; Christian Mhlfeld

Opis

Written by an expanded team of leading international scientists, the second edition thoroughly investigates research and therapies for managing adverse physiological effects of air-borne particles on the respiratory tract. The book examines the lung as the gateway for particle damage to organs outside the respiratory system and provide the information needed to understand and combat the numerous and varied ailments caused by inhaled particles.

Spis treści

Structure and Function of the Lung
Functional Aspects of Lung Structure as Related to Interaction with Particles, Christian M€uhlfeld and Matthias Ochs

Particle Characteristics
Ambient Tropospheric Particles, Paul A. Solomon and Daniel L. Costa
Manufactured Nanoparticles, Robert N. Grass, Ludwig K. Limbach, and Wendelin J. Stark
Particulate Carriers for Pulmonary Drug Delivery, Stephanie Hein, Andreas Henning, Michael Bur, Marc Schneider, and Claus-Michael Lehr

Inhalation of Particles
Deposition, Retention and Clearance, and Translocation of Inhaled Fine and Nano-Sized Particles
in the Respiratory Tract, Winfried M€oller, Wolfgang G. Kreyling, Otmar Schmid, Manuela Semmler-Behnke, and Holger Schulz

Health Effects of Particle Inhalation
The Epidemiology of Particle Health Effects, Joel Schwartz
Cardiovascular Consequences of Particles, Mark W. Frampton, Mark J. Utell, and Jonathan M. Samet
Autonomic Mediation of the Cardiac Responses to Particle Exposure, Beatriz Gonzalez-Flecha
Effects of Airborne Particles on Respiratory Viral Infection, Ilona Jaspers and Katherine Horvath
Airborne Particles and Structural Remodeling of the Lungs, Amy K. Madl, Christopher Carosino, and Kent E. Pinkerton

Cellular and Molecular Mechanisms of Particle Health Effects
Effect of Particles on Mucus and Mucociliary Clearance, Malcolm King
The Role of Surfactant in Particle Exposure, Francis H. Y. Green, Samuel Sch€urch, Matthias Amrein, Peter J. Gerber, and Zoya Leonenko
Nanoparticle–Cell Membrane Interactions, Barbara Rothen-Rutishauser, Fabian Blank, Christian M€uhlfeld, and Peter Gehr
Mechanisms and Processes Underlying Toxicological Responses to Particles, Vicki Stone and Ken Donaldson
Aeroallergen-Lung Interactions, Carsten Schleh and Jens M. Hohlfeld
Dose-Response Relationships, Tobias Stoeger and Otmar Schmid
Index

O autorze

Peter Gehr, Christian Mühlfeld, Barbara Rothen-Rutishauser, Fabian Blank