Kategoria BISAC: Medical >> Pharmacy

The concepts, applications, and practical issues of Quality by Design

Quality by Design (QbD) is a new framework currently being implemented by the FDA, as well as EU and Japanese regulatory agencies, to ensure better understanding of the process so as to yield a consistent and high-quality pharmaceutical product. QbD breaks from past approaches in assuming that drug quality cannot be tested into products; rather, it must be built into every step of the product creation process.

Quality by Design: Perspectives and Case Studies presents the first systematic approach to...

This volume gives an integrated view of how cultured animal cells are used for biopharmaceutical production.

Features research in both illegal and legal drug substances from around the globe such as examinations of FDA approved pharmaceuticals, different methods of drug delivery, and the investigation of illegal distribution of drug products and its effects on substance abuse.

Considers phytoestrogens, natural compounds found in plants that possess oestrogen-like activity. This book addresses the biological and pharmacological significances of identification and analysis of effective components of natural medicines and describes methods and procedures for identification and analysis.

Written by leading American practitioners, the Oxford American Handbooks of Medicine each offer a pocket-sized overview of an entire specialty, featuring instant access to guidance on the conditions that are most likely to be encountered. Precise and prescriptive, the handbooks offer up-to-date advice on examination, investigations, common procedures, and in-patient care. These books will be invaluable resources for residents and students, as well as a useful reference for practitioners.

The Oxford American Handbook of Clinical Pharmacy provides an accessible and easily navigable...

Our four studies highlight the importance of potential drug-drug interactions as a contributing factor in drug safety. Thus, this book contains these studies starting with the evaluation of drug interaction screening programs, continuing with the prevalence of drug-drug interactions during hospitalization and the pharmacist intervention study and ending with a case-control study about risk factors for gastrointestinal bleeding. We conclude, that improvements regarding the awareness of potential drug-drug interactions and a strict management should be implemented. Prescribing drugs with a low...

Covers powerful new tools for drug development

Molecular pathology offers tools and techniques that can greatly enhance the drug discovery and development process, helping to make the promises of personalized medicine a reality. Molecular Pathology in Drug Discovery and Development provides an unmatched guide to this cutting-edge discipline and its applications to pharmaceutical science.

With contributions from leading lights in drug discovery, drug development, and molecular pathology balanced by a consistent editorial approach, this reference offers both an overview of...

The definitive compendium of bioassay procedures and applications

A virtual encyclopedia of key bioassay protocols, this up-to-date, essential resource reviews the methods and applications of bioassays that quantify drug activity and evaluate the validity of pharmacological models.

Demonstrating the specific ways in which various pharmaceutical bioassays interpret the activity of drug molecules, the book covers the evaluation and screening of drug compounds in a wide spectrum of therapeutic categories.

Throughout, the authors use various models to link experimental...

On December 2, 2004, Gwen Olsen's niece Megan committed suicide by setting herself on fire-and ended her tortured life as a victim of the adverse effects of prescription drugs.

Olsen's poignant autobiographical journey through the darkness of mental illness and the catastrophic consequences that lurk in medicine cabinets around the country offers an honest glimpse into alarming statistics and a health care system ranked last among nineteen industrialized nations worldwide. As a former sales representative in the pharmaceutical industry for several years, Olsen learned firsthand how an...

Medicinal or pharmaceutical chemistry is a scientific discipline at the intersection of chemistry and pharmacology involved with designing, synthesising and developing pharmaceutical drugs. This book presents research from around the world in this frontal

Raman spectroscopy has advanced in recent years with increasing use both in industry and academia. This is due largely to steady improvements in instrumentation, decreasing cost, and the availability of chemometrics to assist in the analysis of data.

Pharmaceutical applications of Raman spectroscopy have developed similarly and this book will focus on those applications. Carefully organized with an emphasis on industry issues, Pharmaceutical Applications of Raman Spectroscopy, provides the basic theory of Raman effect and instrumentation, and then addresses a wide...

Encyclopedia of Dietary Supplements presents peer-reviewed, objective entries that rigorously examine the most significant scientific research on basic chemical, preclinical, and clinical data. Designed for healthcare professionals, researchers, and health-conscious consumers, it presents evidence-based information on the major vitamin and mineral micronutrients, herbs, botanicals, phytochemicals, and other bioactive preparations.

Supplements covered include:

• Vitamins, beta-carotene, niacin, and folate
• Omega-3 and omega-6 fatty acids,...

Featuring contributions from an international panel of scientists and researchers, this book presents the most recent findings on the application of colloidal properties in drug delivery systems, contributing to the understanding and improved design of novel and advanced drug delivery applications.

A new perspective on the design of molecular therapeutics is emerging. This new strategy emphasizes the rational complementation of functionality along extended patches of a protein surface with the aim of inhibiting protein/protein interactions. The successful development of compounds able to inhibit these interactions offers a unique chance to selectively intervene in a large number of key cellular processes related to human disease.

Protein Surface Recognition presents a detailed treatment of this strategy, with topics including:

• an extended survey of...

This is the first detailed analysis of an immensely popular 13th c. Arabic guide for pharmacists, from a time in which Jewish physicians and pharmacists worked alongside Muslim and Christian practioners. Minhāj al-dukkān ("How to manage a pharmacy"), by Abū ʾl-Munā al-Kūhīn al-ʿAṭṭār (fl. 1260) is the first attempt to explore the full spectrum of pharmacy in the medieval Arabic world: identification of the materia medica and methods of preparation; pharmacy's place within the sciences and particularly its relationship with...

This volume provides readers with the basic principles and fundamentals of extrusion technology and a detailed description of the practical applications of a variety of extrusion processes, including various pharma grade extruders. In addition, the downstream production of films, pellets and tablets, for example, for oral and other delivery routes, are presented and discussed utilizing melt extrusion. This book is the first of its kind that discusses extensively the well-developed science of extrusion technology as applied to pharmaceutical drug product development and manufacturing. By...

Designed for pharmacy students

Now updated for its Second Edition, Thermodynamics of Pharmaceutical Systems provides pharmacy students with a much-needed introduction to the mathematical intricacies of thermodynamics in relation to practical laboratory applications. Designed to meet the needs of the contemporary curriculum in pharmacy schools, the text makes these connections clear, emphasizing specific applications to pharmaceutical systems including dosage forms and newer drug delivery systems.

Students and practitioners involved in drug discovery, drug delivery, and...