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High-Throughput Lead Optimization in Drug Discovery
ISBN: 9780849372681 / Angielski / Twarda / 256 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. A Single Source on Parallel Synthesis for Lead Optimization
The end of the previous millennium saw an explosion in the application of parallel synthesis techniques for making compounds for high-throughput screening. Over time, it became clear that more thought in the design phase of library development is necessary to generate high quality hits. More recently, the use of parallel synthesis techniques has shifted to applications beyond screening collections. Exploring the nuances of this technology, High-Throughput Lead Optimization in Drug Discovery describes the application... A Single Source on Parallel Synthesis for Lead Optimization
The end of the previous millennium saw an explosion in the application of parall... |
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959,60 zł |
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Chemical and Structural Approaches to Rational Drug Design
ISBN: 9780849378188 / Angielski / Twarda / 288 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. This book is the first to provide both a broad overview of the current methodologies being applied to drug design and in-depth analyses of progress in specific fields. It details state-of-the-art approaches to pharmaceutical development currently used by some of the world's foremost laboratories. The book features contributors from a variety of fields, new techniques, previously unpublished data, and extensive reference lists.
This book is the first to provide both a broad overview of the current methodologies being applied to drug design and in-depth analyses of progress in...
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2074,80 zł |
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Chromatographic Analysis of Pharmaceuticals
ISBN: 9780824797768 / Angielski / Twarda / 542 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Updated and revised throughout, this edition of the text explores the chromatographic methods used for the measurement of drugs, impurities and excipients in pharmaceutical preparations, such as tablets, ointments and injectables. The book includes a table listing the chromatographic date of over 1300 drugs and related substances, including sample matrix analyzed, sample handling procedures, column packings, mobile phase, mode of detection, and more.
Updated and revised throughout, this edition of the text explores the chromatographic methods used for the measurement of drugs, impurities and excipi...
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cena:
1556,10 zł |
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Structure-Based Drug Design
ISBN: 9780824798697 / Angielski / Twarda / 664 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Introduces up-to-date advances in crystallography, nuclear magnetic resonance and molecular modelling techniques. The book explains the application of three-dimensional structural information in the design of pharmaceutical products. It offers explanations of novel methodologies, and presents a practical integration of structure-based design and combinatorial chemistry to augment drug discovery and development.
Introduces up-to-date advances in crystallography, nuclear magnetic resonance and molecular modelling techniques. The book explains the application of...
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cena:
959,60 zł |
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GMP Compliance, Productivity, and Quality : Achieving Synergy in Healthcare Manufacturing
ISBN: 9781574910773 / Angielski / Twarda / 524 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Written by twenty-eight experts, filled with recommendations that can immediately be put into action, this book provides the strategies and tactics required to link and harmonize manufacturing processes with GMP to achieve optimum operability and cost-effective regulatory compliance. Drawn from name brand and generic companies and regulatory and contract organizations across the globe, the contributing authors bring readers a combined 450+ years of hands-on experience. They offer thought-provoking questions to help readers diagnose their company's challenges, needs, and available options, all...
Written by twenty-eight experts, filled with recommendations that can immediately be put into action, this book provides the strategies and tactics re...
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cena:
2074,80 zł |
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Clin-Alert 2001: A Quick Reference to Adverse Clinical Events
ISBN: 9781587160783 / Angielski / Twarda / 270 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Now the adverse drug reaction events reported in the newsletter Clin-Alert during Y2000 have been compiled, organized, re-formatted, indexed, and published in a convenient one-volume reference book, Clin-Alert 2001.
The new book contains the full texts of all 311 reports from Clin-Alert newsletter 2000 issues. The reports have been grouped by fourteen major drug categories and indexed in six different ways for quick look-up. The reports were originally prepared for the Clin-Alert newsletter based on an ongoing search of more than 100 major medical journals, and summarization of key... Now the adverse drug reaction events reported in the newsletter Clin-Alert during Y2000 have been compiled, organized, re-formatted, indexed, and publ...
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cena:
544,64 zł |
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Genomics Drug Discovery
ISBN: 9780470096048 / Angielski / Twarda / 480 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Early characterization of toxicity and efficacy would significantly impact the overall productivity of pharmaceutical R&D and reduce drug candidate attrition and failure. By describing the available platforms and weighing their relative advantages and disadvantages, including microarray data analysis, Genomics in Drug Discovery and Development introduces readers to the biomarker, pharmacogenomic, and toxicogenomics toolbox. The authors provide a valuable resource for pharmaceutical discovery scientists, preclinical drug safety department personnel, regulatory personnel, discovery...
Early characterization of toxicity and efficacy would significantly impact the overall productivity of pharmaceutical R&D and reduce drug candidate at...
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cena:
764,13 zł |
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Qspr/Qsar Studies By Molecular Descriptors
ISBN: 9781560728597 / Angielski / Twarda / 438 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. |
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689,82 zł |
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Medicinal Chemistry Research Progress
ISBN: 9781604565805 / Angielski / Twarda / 271 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Medicinal or pharmaceutical chemistry is a scientific discipline at the intersection of chemistry and pharmacology involved with designing, synthesising and developing pharmaceutical drugs. This book presents research from around the world in this frontal
Medicinal or pharmaceutical chemistry is a scientific discipline at the intersection of chemistry and pharmacology involved with designing, synthesisi...
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897,30 zł |
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Integrin-mediated Interactions between Cells and Biomimetic Materials
ISBN: 9783639042009 / Angielski / Miękka / 232 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. |
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414,39 zł |
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International IT Regulations C
ISBN: 9780470758823 / Angielski / Twarda / 338 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Standards, technologies, and requirements for computer validation have changed dramatically in recent years, and so have the interpretation of the standards and the understanding of the processes involved. International IT Regulations and Compliance brings together current thinking on the implementation of standards and regulations in relation to IT for a wide variety of industries. The book provides professionals in pharmaceutical and semiconductor industries with an updated overview of requirements for handling IT systems according to various Quality Standards and how to ?translate? these...
Standards, technologies, and requirements for computer validation have changed dramatically in recent years, and so have the interpretation of the sta...
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cena:
676,77 zł |
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Biodegradable in Situ Microparticles for Sustained Protein Delivery
ISBN: 9783639076592 / Angielski / Miękka / 332 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. The objective of this work was to evaluate the suitability of in situ forming biodegradable microparticles for the controlled delivery of proteins. Particular goals were: a) to evaluate the flexibility of the release patterns of in situ implant and in situ microparticle formulations using hen egg white lysozyme as model protein; b) to characterize, if and how the integrity of the model protein is affected by formulation ingredients, the manufacturing process, storage of the ISM and the release from the formulations; c) to optimize protein delivery from in situ forming implant and...
The objective of this work was to evaluate the suitability of in situ forming biodegradable microparticles for the controlled delivery of proteins. Pa...
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cena:
414,39 zł |
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Drug-Induced Mitochondrial Dysfunction
ISBN: 9780470111314 / Angielski / Twarda / 652 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. This is the definitive, one-stop resource on preclinical drug evaluation for potential mitochondrial toxicity, addressing the issue upfront in the drug development process. It discusses mitochondrial impairment to organs, skeletal muscle, and nervous systems and details methodologies used to assess mitochondria function. It covers both in vitro and in vivo methods for analysis and includes the latest models. This is the authoritative reference on drug-induced mitochondrial dysfunction for safety assessment professionals in the pharmaceutical industry and for pharmacologists and toxicologists...
This is the definitive, one-stop resource on preclinical drug evaluation for potential mitochondrial toxicity, addressing the issue upfront in the dru...
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cena:
944,31 zł |
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Pharmaceutical Packaging Technology
ISBN: 9780748404407 / Angielski / Twarda / 646 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Pharmaceutical packaging is regarded as an integral part of the end pharmaceutical/drug product. This text is structured to meet the needs of the global market, and assesses a wide range of current knowledge, catering both for the requirements of the pharmaceutical industry in the 1990s, as well as for pharmaceutical companies in emerging nations who are still seeking a basic grounding in the subject. The author integrates information on many drug delivery systems, where the packaging is an essential component of the product, to produce a book for all those dealing with the topic.
Pharmaceutical packaging is regarded as an integral part of the end pharmaceutical/drug product. This text is structured to meet the needs of the glob...
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cena:
2723,18 zł |
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computational drug design: a guide for computational and medicinal chemists
ISBN: 9780470126851 / Angielski / Twarda / 344 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Helps you choose the right computational tools and techniques to meet your drug design goals
Computational Drug Design covers all of the major computational drug design techniques in use today, focusing on the process that pharmaceutical chemists employ to design a new drug molecule. The discussions of which computational tools to use and when and how to use them are all based on typical pharmaceutical industry drug design processes. Following an introduction, the book is divided into three parts:
Helps you choose the right computational tools and techniques to meet your drug design goals
Computational Drug Design covers all of the maj... |
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638,55 zł |
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Sābūr Ibn Sahl's Dispensatory in the Recension of the ʿaḍudī Hospital
ISBN: 9789004171244 / Angielski / Twarda / 270 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. This book offers an Arabic edition and English translation of Sābūr ibn Sahl's (d. 869 CE) famous dispensatory as preserved in a recension made by the physicians of the ʿAḍudī hospital in Baghdad around the middle of the 11th century CE. Drawing on different exponents of Sābūr's original, the recension also constituted an attempt at revising the pharmacological material on empirical grounds. Edition and translation are framed by a detailed introductory study and various medico-pharmacological glossaries. The book thus not only highlights the lasting impact...
This book offers an Arabic edition and English translation of Sābūr ibn Sahl's (d. 869 CE) famous dispensatory as preserved in a recension m...
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cena:
586,26 zł |
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International Pharmaceutical Marketing.
ISBN: 9780899300092 / Angielski / Twarda / 281 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. International Pharmaceutical Marketing is an authoritative study of the world pharmaceutical industry from a marketing perspective. Dr. Pradhan, a respected expert in pharmaceutical economics, provides a broad-based discussion of the subject, including international marketing and organization, exporting, investing and licensing, product registration, patents, and new drug development. International pharmaceutical market research, product and pricing policy, promotional activities, and distribution systems are investigated and described in detail. Finally, the author focuses on the... International Pharmaceutical Marketing is an authoritative study of the world pharmaceutical industry from a marketing perspective. Dr. Pradhan, a ... |
cena:
436,80 zł |
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Advances in Chromatography: Volume 15
ISBN: 9780824765002 / Angielski / Twarda / 354 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. |
cena:
1011,47 zł |
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Drug Discovery: A Casebook and Analysis
ISBN: 9780896031807 / Angielski / Twarda / 438 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. This treatise had its origins in the authors' strong opinion that the discovery of new drugs, especially of innovative therapeutic agents, really does not happen as a spontaneous sequel to investiga tive research, no matter how penetrating such research may be. Rather, it seemed to us that the discovery of innovative therapeutic agents was a very active process, existing in and of itself, and demanding full attention-it was not simply a passive, dependent by-process of investigative research. And yet, many researchers some close confreres of the authors, others more distant-believed...
This treatise had its origins in the authors' strong opinion that the discovery of new drugs, especially of innovative therapeutic agents, really does...
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cena:
574,29 zł |
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Fluorine in Medicinal Chemistry and Chemical Biology
ISBN: 9781405167208 / Angielski / Twarda / 640 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. The extraordinary potential of fluorine-containing molecules in medicinal chemistry and chemical biology has been recognized by researchers outside of the traditional fluorine chemistry field, and thus a new wave of fluorine chemistry is rapidly expanding its biomedical frontiers. With several of the best selling drugs in the world crucially containing fluorine atoms, the incorporation of fluorine to drug leads has become an essential practice in biomedical research, especially for drug design and discovery as well as development.
Focusing on the unique and significant roles that fluorine... The extraordinary potential of fluorine-containing molecules in medicinal chemistry and chemical biology has been recognized by researchers outside of...
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cena:
1015,29 zł |
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