Kategoria BISAC: Medical >> Forensic Medicine

Cancer is a multifaceted and genomically complex disease and data obtained through high throughput technologies has provided near complete resolution of landscape of how genomic, genetic and epigenetic mutations in cancerous cells effectively influence homeostasis of signaling networks within these cells, between cancerous cells, tumor microenvironment and at the organ level. Increasing sophisticated information has helped us in developing a better understanding of the underlying mechanisms of cancer and it is now know that intra-tumor genetic heterogeneity, cellular plasticity,...

Forensic Anthropology serves as a graduate level text for those studying and teaching forensic anthropology, as well as an excellent reference for forensic anthropologist libraries or for use in casework. Covers taphonomy, recovery and analysis, identification, statistical interpretation, and professional issues. Edited by a world-renowned leading forensic expert, the Advanced Forensic Science Series grew out of the recommendations from the 2009 NAS Report, Strengthening Forensic Science: A Path Forward, and is a long overdue solution for the forensic science...

This edited volume is about novel targeted therapies for the treatment of advanced neoplasms of the head and neck (HNSCC) with particular reference to oral squamous cell carcinomas and covers specific fields of cancer genetics and genomics for personalized medicine.

The landmark studies from the HNSCC Cancer Genome Anatomy (TCGA) and the cancer Genome Atlas 2015 have revealed the multiplicity and diversity of genetic alterations in HNSCC. This remarkable body of information has elucidated novel druggable targets (eg. EGFR, mTOR, p53, survivin and aberrant microRNA) for...

Essentials of Medicolegal Death Investigation uses a unique approach by combining medical issues, injury patterns, and investigative procedures to provide the reader with the basic fundamentals for a death investigation. The text introduces the reader to death investigation, common causes of death, and very specific types of death, including blunt-force injuries, gunshot wounds, and toxicology deaths. Each section includes case studies with written and visual descriptions. Written by a well-known and experienced medicolegal death investigator, the book fills a void in...

Osteoarchaeology: A Guide to the Macroscopic Study of Human Skeletal Remains covers the identification of bones and teeth, taphonomy, sex, ancestry assessment, age estimation, the analysis of biodistances, growth patterns and activity markers, and paleopathology.

The book aims to familiarize the reader with the main applications of osteoarchaeology and provide the necessary knowledge required for the implementation of a broad range of osteological methods. It is ideal as a complement to existing textbooks used in upper level undergraduate and graduate courses on...

This volume covers the most important areas of glioblastoma - surgical resection, molecular pathology, targeted therapies, cancer stem cells, the role of DNA methylation, targeted sequencing for personalized therapy, animal models and advances in pediatric glioblastoma. Chapter authors are junior and senior investigators, who are well established in their particular areas and include neurosurgeons, neuropathologists, neurooncologists and basic scientists.

This volume explores various approaches for enrichment, detection, isolation, and molecular profiling of circulating tumor cells (CTCs). Each chapter provides comprehensive descriptions and guidelines on how to perform innovative experiments in CTC research. Included are protocols for capture of CTCs via filtration and density gradient centrifugation; microfluidic and immunomagnetic separation of CTCs; detection of CTCs by immunocytochemistry, fluorescence in situ hybridization, and flow cytometry; assays designed for genomic characterization and functional analyses of CTCs, and...

Through the innovative perspective of environment and culture, Urmi Engineer Willoughby examines yellow fever in New Orleans from 1796 to 1905. Linking local epidemics to the city's place in the Atlantic world, Yellow Fever, Race, and Ecology in Nineteenth-Century New Orleans analyzes how incidences of and responses to the disease grew out of an environment shaped by sugar production, slavery, and urban development.

Willoughby argues that transnational processes--including patterns of migration, industrialization, and imperialism--contributed to ecological changes that...

Zika Virus provides an authoritative account of one of most fascinating viruses of the 21st century, covering all the main points. It includes coverage of clinical manifestations, such as fever and fatigue, but also delves into neurological manifestations like acute demyelinating neuropathy. In addition, the book discusses new evidence that suggests that Zika fever in pregnant women can cause abnormal brain development in fetuses by mother-to-child transmission. The Zika virus infection has become one of the first where women are actively discouraged from getting pregnant. Readers...