Kategoria BISAC: Medical >> Dermatology

Cutaneous Cryosurgery is an invaluable practical guide for the management of benign, premalignant, and malignant skin lesions. The book provides practitioners with all the information needed to add cryosurgery to their surgical repertoire. For practitioners already using cryosurgery, many pearls are provided to expand the use of cryosurgery for new indications along with helpful tips for the use of cutting-edge cryosurgical equipment.

This new edition of an established reference uses an evidence-based approach, including a chapter reviewing the evidence for using...

This textbook provides a detailed treatment of the histopathology of blistering diseases. In a succinct manner, it covers the clinical features, the immunofluorescence and the electron microscopic findings. It is supplemented by selected references and encompasses the new discoveries which occurred in recent years concerning the molecular aetiology of these diseases. It represents the first book in the field of blistering diseases which contains an in-depth account of histopathology and correlates it with the clinical features and the molecular biology in an unique didactic style.

Cytokines and cytokine receptors remain an area of great interest for the development of targeted therapies for cutaneous inflammatory diseases. Anti-TNF therapeutics have proven to be effective in the treatment of psoriasis, and clinical investigations have now begun for other cytokine-directed therapies, such as those targeting IFN-g, IL-12p40, and IL-18. In addition to therapeutics that target cytokines directly, strategies that target cytokine signaling pathways are in development. This book summarizes the findings of the 56^th International Workshop of the Ernst Schering...

Pharmaceutical companies are spending increasing amounts of money on drug discovery and development. Nevertheless, attrition rates in clinical development are still very high, and up to 90% of new compounds fail in clinical phase I - III trials, which is partially due to lack of clinical efficacy. This indicates a strong need for highly predictive in vitro and in vivo models. The "50th International Workshop of the Ernst Schering Research Foundation" focussed on "Animal Models of T Cell-Mediated Skin Diseases." Such animal models should have impact not only on inflammatory dermatoses but...