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Leukocyte Recruitment, Endothelial Cell Adhesion Molecules, and Transcriptional Control: Insights for Drug Discovery
ISBN: 9780792372233 / Angielski / Twarda / 327 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. The localized attachment of circulating leukocytes to endothelium has been recognized as the cellular hallmark of the inflammatory response. This adhesive interaction, a necessary antecedent to the emigration of leukocytes from the blood into the tissues, is mediated by vascular adhesion molecules. Leukocyte Recruitment, Endothelial Cell Adhesion Molecules and Transcriptional Control: Insights for Drug Discovery outlines some of the cellular and molecular mechanisms of inflammation with contributions from top researchers.
This volume provides an overview of three of... The localized attachment of circulating leukocytes to endothelium has been recognized as the cellular hallmark of the inflammatory response. This adhe...
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cena:
603,81 |
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Selenium: Its Molecular Biology and Role in Human Health
ISBN: 9780792373353 / Angielski / Twarda / 326 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. As discussed in this book, a large body of evidence indicates that selenium is a cancer chemopreventive agent. Further evidence points to a role of this element in reducing viral expression, in preventing heart disease, and other cardiovascular and muscle disorders, and in delaying the progression of AIDS in HIV infected patients. Selenium may also have a role in mammalian development, in male fertility, in immune function and in slowing the aging process. The mechanism by which selenium exerts its beneficial effects on health may be through selenium-containing proteins. Selenium is...
As discussed in this book, a large body of evidence indicates that selenium is a cancer chemopreventive agent. Further evidence points to a role of th...
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cena:
474,14 |
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Molecular Mechanisms of Metal Toxicity and Carcinogenesis
ISBN: 9780792374985 / Angielski / Twarda / 242 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. During the last two decades, chemical and cellular studies have contributed enormously to our understanding of metal-induced carcinogenesis, and many hypotheses on the role of metals in pathophysiological processes have been investigated. In addition, new techniques are available to shed light on the mechanism of carcinogenesis in molecular terms. This conference on Molecular Mechanisms of Metal Toxicity and Carcinogenesis in September 2000 focused on the latest research in molecular mechanisms of metal-induced toxicity and carcinogenesis. The conference promoted a multidisciplinary...
During the last two decades, chemical and cellular studies have contributed enormously to our understanding of metal-induced carcinogenesis, and many ...
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cena:
603,81 |
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Chemistry and Biology of Pteridines and Folates: Proceedings of the 12th International Symposium on Pteridines and Folates, National Institutes of Hea
ISBN: 9780792376750 / Angielski / Twarda / 677 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Pteridine and folate research has long been recognized as important for many biological processes, such as amino acid metabolism, nucleic acid synthesis, neurotransmitter synthesis, cancer, cardiovascular function, and growth and development of essentially all living organisms. Defects in synthesis, metabolism and/or nutritional availability of these compounds have been implicated as major causes of common disease processes, e.g. cancer, inflammatory disorders, cardiovascular disorders, neurological diseases, autoimmune processes, and birth defects.
Since pteridine and folate biology... Pteridine and folate research has long been recognized as important for many biological processes, such as amino acid metabolism, nucleic acid synthes...
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cena:
603,81 |
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Acid-Base Physiology: A Direct Approach
ISBN: 9780801863615 / Angielski / Miękka / 144 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. This book develops a scientific approach to the study of clinical acid-base physiology, giving emphasis to the areas of most significance in diagnosis and therapy. This book develops a scientific approach to the study of clinical acid-base physiology, giving emphasis to the areas of most significance in diagno... |
cena:
161,77 |
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Iron, Nature's Universal Element: Why People Need Iron and Animals Make Magnets
ISBN: 9780813528311 / Angielski / Twarda / 224 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Virtually all life on Earth, from bacteria to humans, needs iron to survive. From facilitating oxygen flow in mammals to assisting migrating birds in finding their way south for the winter, iron serves a variety of definitive roles for nearly all living creatures.Our knowledge of iron s role in life is the result of recent discoveries about iron and magnetism in bacteria, in myriad animals and plant species, and in humans. Personal stories of scientists illustrate the lively interplay between molecular biologists, ornithologists, physicists, oceanographers, chemists, geologists,...
Virtually all life on Earth, from bacteria to humans, needs iron to survive. From facilitating oxygen flow in mammals to assisting migrating birds in ...
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cena:
184,60 |
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Immunocytochemistry and in Situ Hybridization in the Biomedical Sciences
ISBN: 9780817640651 / Angielski / Twarda / 267 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Immunochemistry and in situ hybridization are widely used biomedical sciences. This survey aims to serve as a reference source in any laboratory setting. Numerous examples of techniques in biomedical sciences are included, as well as experimental assays and practical tips.
Immunochemistry and in situ hybridization are widely used biomedical sciences. This survey aims to serve as a reference source in any laboratory setti...
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cena:
407,16 |
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Proinflammatory and Antiinflammatory Peptides
ISBN: 9780824701208 / Angielski / Twarda / 756 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. "Analyzes the role of peptides in promoting or suppressing inflammation. Thoroughly examines the therapeutic potential of key peptides, analogs, agonists, and antagonists that influence cell injury and repair."
"Analyzes the role of peptides in promoting or suppressing inflammation. Thoroughly examines the therapeutic potential of key peptides, analogs, agoni...
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cena:
1044,44 |
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G Protein-Coupled Receptors in Drug Discovery
ISBN: 9780824725730 / Angielski / Twarda / 376 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. The broad range of G protein-coupled receptors (GPCRs) encompasses all areas of modern medicine and have an enormous impact on the process of drug development. Using disease-oriented methods to cover everything from screening to expression and crystallization, G Protein-Coupled Receptors in Drug Discovery describes the physiological roles of GPCRs and their involvement in various human diseases.
The book presents current approaches in drug discovery that include target selection, establishment of screening and functional assays. It also covers recombinant GPCR expression for drug... The broad range of G protein-coupled receptors (GPCRs) encompasses all areas of modern medicine and have an enormous impact on the process of drug dev...
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cena:
922,99 |
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Phytochemicals in Health and Disease
ISBN: 9780824740238 / Angielski / Twarda / 384 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. " well-written and the content is clearly presented. There are plentiful figures and tables, which are effectively labeled and adequately support the content. highly recommended for academic and special libraries. effectively presents current research on phytochemicals in a readable manner."
- E-Streams "This landmark volume shows how far the field has advanced . This important volume is filled with reports on what the editors term as the 'new era' in the study of phytochemicals, in which we move from the 'eat more vegetable and fruit' admonition to more detailed information on the... " well-written and the content is clearly presented. There are plentiful figures and tables, which are effectively labeled and adequately support the ...
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cena:
1263,03 |
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Nutraceutical Proteins and Peptides in Health and Disease
ISBN: 9780824753542 / Angielski / Twarda / 688 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Reports of the beneficial health effects of some peptides have begun to make their way into the scientific literature. Peptides can act as immunomodulators, and have been shown to have a positive influence on calcium absorption, and on regulation of serum cholesterol. A number of peptides may also possess antimicrobial properties that enhance the body's defense mechanisms, and others may produce inhibitory effects for angiotensin-I-converting enzyme (ACE), leading to novel treatments for blood pressure conditions, heart failure, and diabetes. Modern food biotechnology may also allow for the...
Reports of the beneficial health effects of some peptides have begun to make their way into the scientific literature. Peptides can act as immunomodul...
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cena:
1117,31 |
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Carotenoids in Health and Disease
ISBN: 9780824754167 / Angielski / Twarda / 576 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. The first source to collect the latest evidence linking carotenoids to human health and disease, this stimulating reference studies the role of carotenoids in the prevention of chronic disease and reviews breakthrough studies from more than 40 field authorities on the latest research. The book reveals the most recent findings regarding the use of carotenoids in the prevention of cancers and sunburn, as well as eye, heart, vascular, and photosensitivity diseases, and evaluates the potential toxic effects of high-dose carotenoids in both smokers and drinkers. It also focuses on pioneering...
The first source to collect the latest evidence linking carotenoids to human health and disease, this stimulating reference studies the role of carote...
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cena:
1263,03 |
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Protein Discovery Technologies
ISBN: 9780824754686 / Angielski / Twarda / 272 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. A True Insider s Guide to the Field Then and Now Until now, there has not been a book that effectively addresses the historical basis of protein discovery. Featuring contributions from a distinguished international panel of experts, Protein Discovery Technologies elucidates the principles, techniques, strategies, and broad range of applications of protein discovery by documenting the often untold stories and personal accounts of the contributors past scientific achievements. Incorporates Short, Personal Discovery... A True Insider s Guide to the Field Then and Now Until now, there has not been a book that effectively addresses the histo... |
cena:
922,99 |
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Principles of Enzymology for the Food Sciences
ISBN: 9780824791483 / Angielski / Twarda / 648 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. This second edition explains the fundamentals of enzymology and describes the role of enzymes in food, agricultural and health sciences. Among other topics, it provides new methods for protein determination and purification; examines the novel concept of hysteresis; and furnishes new information on proteases, oxidases, polyphenol oxidases, lipoxygenases and the enzymology of biotechnology.
This second edition explains the fundamentals of enzymology and describes the role of enzymes in food, agricultural and health sciences. Among other t...
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cena:
1165,88 |
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Concise Biochemistry
ISBN: 9780824797362 / Angielski / Miękka / 636 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. This work offers succinct, medically-oriented coverage of biochemistry, examining biologically important materials and presenting the properties of nucleic acids as well as nucleic acid metabolism. Each metabolic process is integrated in a review of overall energy metabolism, diabetes and starvation. A solutions manual is available to instructors only.
This work offers succinct, medically-oriented coverage of biochemistry, examining biologically important materials and presenting the properties of nu...
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cena:
437,16 |
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Reactive Oxygen Metabolites: Chemistry and Medical Consequences
ISBN: 9780849308918 / Angielski / Twarda / 608 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. In recent years, the field of radical chemistry has undergone explosive growth. Although its roots lie in organic chemistry, the implications of its findings are having enormous impact in a broad range of disciplines, and we now have evidence for radical involvement in over 100 diseases. As important as this is, however, the subject of radicals and reactive oxygen metabolites (ROMs) is complex and barely touched upon in the curriculum of medical schools.
Reactive Oxygen Metabolites brings the subject within the grasp of even those with little preparation in chemistry. From the basic... In recent years, the field of radical chemistry has undergone explosive growth. Although its roots lie in organic chemistry, the implications of its f...
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cena:
1214,46 |
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Calcium Signalling in Cancer
ISBN: 9780849309427 / Angielski / Twarda / 384 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Calcium signalling occupies a preeminent position in the signal transduction system of the cell by virtue of its participation in a wide range of physiological functions together with the biological events associated with genetic expression, cell proliferation and apoptosis, as well as cell differentiation and morphogenesis. It is an important feature of cell adhesion and motility; the integrity of the calcium binding proteins themselves is a basic requirement of normal biological function. In fact, the deregulation of calcium signaling is now regarded as the primary event in the...
Calcium signalling occupies a preeminent position in the signal transduction system of the cell by virtue of its participation in a wide range of phys...
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cena:
1214,46 |
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Flavonoids : Chemistry, Biochemistry and Applications
ISBN: 9780849320217 / Angielski / Twarda / 1237 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. < P> Advances in the flavonoid field have been nothing short of spectacular over the last 20 years. While the medical field has noticed flavonoids for their potential antioxidant, anticancer and cardioprotectant characteristics, growers and processors in plant sciences have utilized flavonoid biosynthesis and the genetic manipulation of the flavonoid pathway in plants to improve the nutritional and ornamental value of crops. Flavonoids: Chemistry, Biochemistry and Applications covers each class of flavonoid and presents the historic advances made in flavonoid research since the 1994...
< P> Advances in the flavonoid field have been nothing short of spectacular over the last 20 years. While the medical field has noticed flavonoids for...
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cena:
1797,40 |
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Amyloid Precursor Protein: A Practical Approach
ISBN: 9780849322457 / Angielski / Twarda / 240 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. In the search for an effective treatment for Alzheimer's disease, APP is a unique model protein that illustrates the wide array of basic and sophisticated characterization techniques available.
Exploring a variety of biological techniques to clarify the structure and function of this transmembrane protein, this text presents each method with detailed, step-by-step protocols to achieve reproducible results and provide a framework for studying other membrane proteins. In the search for an effective treatment for Alzheimer's disease, APP is a unique model protein that illustrates the wide array of basic and sophistic...
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cena:
1068,72 |
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G Protein-Coupled Receptors: Structure, Function, and Ligand Screening
ISBN: 9780849327711 / Angielski / Twarda / 336 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. This book provides a broad base of knowledge of G-protein-coupled receptors. Useful at both the university and industrial levels, this book is of particular interest to those who are developing therapeutic approaches to diseases using drugs that influence receptor activation.
This book provides a broad base of knowledge of G-protein-coupled receptors. Useful at both the university and industrial levels, this book is of part...
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cena:
1214,46 |