Blending the latest research and educational theory with sound and effective practices, this book shows you how to create a learning-centered library for the new millennium. Some of the most respected authorities in the field have contributed their ideas and expertise to this important work. For example, Carol Kuhlthau discusses student learning in the information age; Jackie Mancall writes about collection development; Sheila Salmon describes what the library media specialist brings to the equation of standards-based learning; and Joy McGregor provides an informative article about...

This third entry in the Principles and Practice series focuses on the role of the library media specialist as a change agent in the school. The purpose of this book is twofold: to provide insight into the role of the school librarian as change agent and to demonstrate strategies for being an effective change agent using a subset of current reform initiatives. The authors are educators, library media specialists, and researchers who share a common belief in the ability of classroom teachers, administrators, library media specialists, parents, and community members to work together to create...

Following the succesful publication of "Proteome and Protein Analysis" in 2000, which was based on a former MPSA (Methods in Protein Structure Analysis) conference, Methods in Proteome and Protein Analysis presents the most interesting papers from the 14^th MPSA meeting.

Major topics include: protein and peptide sample preparation and separation; new reagent for protein sequence analysis; mass spectrometry in protein research; analysis of posttranslational modification; protein-protein interaction using MALDI-MS; manipulation of genome or functional...

Mammalian and Avian Transgenesis presents a collection of novel methods for the production of a wide range of transgenic animals. The manual focuses largely on mice, but also contains protocols for successful transgenesis in rats, cows, pigs and birds.

The manual provides detailed, step-by-step protocols covering all aspects of the production of transgenic animals, including the use of lentiviral vectors in gene transfer, intracytoplasmic sperm injection, nuclear transfer, large insert transgenesis, conditional gene expression systems, the use of reporter genes in...

Imaging Cellular and Molecular Biological Function provides a unique selection of essays by leading experts, aiming at scientist and student alike who are interested in all aspects of modern imaging, from its application and up-scaling to its development. The chapter content ranges from the basic through to complex overview of method and protocols, and there is also practical and detailed how-to content on important, but rarely addressed topics. This first edition features all-colour-plate chapters.

The philosophy of this volume is to provide student, researcher, PI, professional...

This book opens with a description of fundamental aspects of protein adsorption to surfaces, a phenomenon that plays a key role in biotechnological applications, especially at solid-liquid interfaces. Presented here are methods for studying adsorption kinetics and conformational changes such as optical waveguide lightmode spectroscopy (OWLS). Also described are sensitive bench techniques for measuring the orientation and structure of proteins at solid-liquid interfaces, including total internal reflection ellipsometry (TIRE), dual polarisation interferometry (DPI) and time of flight -...