Although rare, retinoblastoma has been at the fore- fortunate; while in the developed world eye preser- front of cancer research and treatment for the last tion has become a priority, developing countries c- three decades. The two-hit hypothesis of oncogenesis tinue to face delays in diagnosis, poor access to care, proposed by Alfred Knudson provided the conceptual and suboptimal treatment - the problem in the less framework for tumor suppressor gene research and developed world is cure. led to the discovery of the retinoblastoma pathway as In this book, we have invited a team of experts to a...
Although rare, retinoblastoma has been at the fore- fortunate; while in the developed world eye preser- front of cancer research and treatment for the...
Pediatric Oncology Nursing: Advanced Clinical Hand- signs, diagnostic and laboratory procedures, tre- book is a joint effort between nurses in Canada, the ment, prognosis, and follow up care are included for United Kingdom, and the United States. This is the each of the disorders. second edition, and has been another wonderful Part III covers cancer treatment, including c- opportunity to bring together the expertise of hema- motherapy, radiation therapy, hematopoetic stem cell tology and oncology nurses from two continents. The transplantation, surgery, gene therapy, biotherapy, c- book is...
Pediatric Oncology Nursing: Advanced Clinical Hand- signs, diagnostic and laboratory procedures, tre- book is a joint effort between nurses in Canada,...
Serves as a comprehensive and up-to-date compendium on the biology, diagnosis, and treatment of childhood leukemia Focuses especially on genomic approaches to risk stratification and the use of risk-adjusted treatment approaches Includes detailed discussion of promising targeted agents and strategies for the development of new agents Will prove invaluable to specialists, generalists and trainees alike. This book is a comprehensive and up-to-date compendium on all aspects of childhood acute lymphoblastic and acute myeloid leukemia, which together constitute the most frequent cancer in the...
Serves as a comprehensive and up-to-date compendium on the biology, diagnosis, and treatment of childhood leukemia Focuses especially on genomic appro...
The field of liver tumors in children has seen huge therapeutic advances over recent years. This book offers an update on this complex and rapidly evolving field. It discloses how the outcome of a previously devastating disease has been dramatically improved.
The field of liver tumors in children has seen huge therapeutic advances over recent years. This book offers an update on this complex and rapidly ...
The purpose of this book is to integrate the most re- butions and support of my colleagues and friends cent advances in the diagnosis and treatment of pedi- at The University of Texas Southwestern Medical atric bone and soft tissue sarcomas. The book is di- School, St. Jude Children s Research Hospital, and the vided into two major sections, the ?rst of which pres- Hospital for Sick Children in Toronto. In particular, I ents salient concepts in epidemiology, the impact of would like to thank Drs. George Buchanan, Charles novel tools in imaging and molecular biology, and the Pratt, William...
The purpose of this book is to integrate the most re- butions and support of my colleagues and friends cent advances in the diagnosis and treatment of...
Pediatric CNS Tumors is a detailed review of childhood brain tumors with a particular emphasis on providing treatment algorithms for each tumor type. Controversies and current therapeutic agents under development are also discussed. The second edition includes expanded chapters on embryonal tumors, rare tumor types, and supportive care for patients with brain tumors.
Pediatric CNS Tumors is a detailed review of childhood brain tumors with a particular emphasis on providing treatment algorithms for each tumor typ...
Germ cell tumors are relatively rare compared with other malignancies, and compilations of knowledge that encompass the entire spectrum of the disease are lacking. This textbook, written by the foremost authorities in the field, rectifies the situation by discussing in depth a broad range of topics, including biology, epidemiology, pathology, treatment, and late effects. Bearing in mind that germ cell tumors are most prevalent in the adolescent and young adult age group, causes of disease and treatment approaches in pediatric and adult patients are compared and contrasted. By spanning the...
Germ cell tumors are relatively rare compared with other malignancies, and compilations of knowledge that encompass the entire spectrum of the disease...
This book is a comprehensive guide that will help medical professionals pediatric oncologists, nurses, pediatricians, family practitioners, internists, radiation oncologists, surgeons to understand and manage the long-term effects of treatment for childhood and adolescent cancer. The consequences of treatment are described for each organ system, with explanation of pathophysiology, clinical manifestations, detection and screening and management. Disease- and organ-based algorithms of care and tables designed to facilitate the assessment of late effects are highlights of the book and will...
This book is a comprehensive guide that will help medical professionals pediatric oncologists, nurses, pediatricians, family practitioners, interni...
This book is a comprehensive and up-to-date compendium on all aspects of blood and marrow transplantation in children. After an introductory chapter describing the history of pediatric blood and marrow transplantation, subsequent chapters discuss pediatric-specific aspects of transplantation, including stem cell sources suitable for transplantation, preparative regimens, graft-versus-host disease, complications related to transplantation, and late effects. The role of blood and marrow transplantation in various specific pediatric diseases is then examined, and the closing chapter considers...
This book is a comprehensive and up-to-date compendium on all aspects of blood and marrow transplantation in children. After an introductory chapter d...