Retinoblastoma

ISBN-13: 9780387890715 / Angielski / Twarda / 2010 / 156 str.

Carlos Rodriguez-Galindo

Opis

Although rare, retinoblastoma has been at the fore- fortunate; while in the developed world eye preser- front of cancer research and treatment for the last tion has become a priority, developing countries c- three decades. The two-hit hypothesis of oncogenesis tinue to face delays in diagnosis, poor access to care, proposed by Alfred Knudson provided the conceptual and suboptimal treatment - the problem in the less framework for tumor suppressor gene research and developed world is cure. led to the discovery of the retinoblastoma pathway as In this book, we have invited a team of experts to a key element in cancer development. More recently, address all those important aspects of retinoblastoma the treatment of children with retinoblastoma has also research and therapy - from biology to epidemiology provided a model for modern approach to the can- to treatment. We hope that in subsequent editions we cer patient; state of the art retinoblastoma treatment will be able to continue to provide updates on such can only be conceived in the context of the multidis- exciting subjects.

Recenzje

From the reviews:

"This thorough reference, although it covers nearly every imaginable aspect of retinoblastoma, is ... a concise and easy read. ... this book is a wonderful introduction to retinoblastoma for physicians in training. The authors have successfully achieved their goal of compiling a comprehensive book addressing the history, diagnosis, treatment, and future research in this field. ... This is a valuable addition to the literature, providing as it does a single resource that addresses the complexities of treating retinoblastoma." (Christina H. Choe, Doody's Review Service, October, 2010)

Spis treści

Chapter 1: Biology of Retinoblastoma

Chapter 2: Epidemiology

Chapter 3: Clinical Features, Diagnosis, Pathology

Chapter 4: Genetics of Retinoblastoma and Genetic Counseling

Chapter 5: Radiation Therapy in the Management of Retinoblastoma

Chapter 6: Chemotherapy in the Management of Retinoblastoma

Chapter 7: Treatment of Intraocular Retinoblastoma

Chapter 8: Treatment of Extraocular and Metastatic Retinoblastoma

Chapter 9: Second Malignancies and Other Long Term Effects in Retinoblastoma Survivors

Chapter 10: Visual Rehabilitation

Chapter 11: Retinoblastoma in Developing Countries

Blurb

Treatment of retinoblastoma has evolved at a significant speed over the last two decades; ocular salvage approaches are now at the core of modern treatments, and assessment of visual and functional outcomes has become a priority. New discoveries in retinoblastoma biology are leading the way to the development of targeted therapies that could revolutionize our current approaches to the treatment. In this book, experts address all the important aspects of research and therapy - from biology to epidemiology to treatment. Retinoblastoma will provide a single source for the diagnosis and care of children with this malignancy.