Serves as a comprehensive and up-to-date compendium on the biology, diagnosis, and treatment of childhood leukemia Focuses especially on genomic approaches to risk stratification and the use of risk-adjusted treatment approaches Includes detailed discussion of promising targeted agents and strategies for the development of new agents Will prove invaluable to specialists, generalists and trainees alike. This book is a comprehensive and up-to-date compendium on all aspects of childhood acute lymphoblastic and acute myeloid leukemia, which together constitute the most frequent cancer in the...

This book is a comprehensive and up-to-date compendium on all aspects of childhood leukemia. After introductory chapters on the epidemiology and biology of pediatric leukemia, treatment considerations are extensively reviewed, with emphasis on the use of risk-adjusted treatment approaches. Promising targeted agents are discussed, and strategies for the development of new agents are appraised. The late effects of leukemia and its therapy are then considered in depth, with due attention to management of the psychosocial impact of the disease. Finally, global strategies to improve leukemia care...

After an introductory chapter describing the history of pediatric blood and marrow transplantation, subsequent chapters discuss pediatric-specific aspects of transplantation, including stem cell sources suitable for transplantation, preparative regimens, graft-versus-host disease, complications related to transplantation, and late effects.

This book presents the current clinical evidence on the efficacy of herbal and nutritional treatments for anxiety that is experienced in association with psychiatric disorder, and explains how health professionals can apply this knowledge to the benefit of patients presenting with a wide range of symptoms, including comorbid mood disorders.

This book presents the latest scientific knowledge on inherited and acquired bone marrow failure syndromes, describing the advances in understanding of genetics and pathophysiology that have been achieved as a result of high-throughput DNA sequencing, RNA expression studies, and modern biochemistry techniques.

This book is a comprehensive and up-to-date compendium of all aspects of brain tumors in children. The concluding chapters present critical information relevant to survivorship, neurocognitive and other late effects, and the global challenges to better diagnosis and treatment of brain tumors in children.