In eukaryotes many vital cellular functions like metabolism, motility, secretion, growth, differentiation are ultimately regulated by protein phosphorylation/dephosphorylation. Extracellular signals which trigger thesechanges control protein kinases and protein phosphatases. It is the aim of this volume to unveil signal networks which connect extracellular signals via second messengers with chages of the phosphorylation state of target proteins.
In eukaryotes many vital cellular functions like metabolism, motility, secretion, growth, differentiation are ultimately regulated by protein phosphor...
For those working and interested in the field of chloroplast ribosomes, an ideal overview is provided by this text. Topics covered include: Plastid rRNAs and tRNAs; Structure, Organization and Expression of Their Genes; Plastid Ribosomal Proteins and Their Genes in Higher Plants; Plastid Ribosomes and Factors of Algae and of Cyanelles; Functional Aspects; Physiological Aspects. Stressed is the fact that biosynthesis and function of the translational apparatus relies upon two separate genetic systems and thus produce particular regulatory problems with fundamental significance. The...
For those working and interested in the field of chloroplast ribosomes, an ideal overview is provided by this text. Topics covered include: Plastid rR...
Interest in the biological effects of ionising radiation closely followed the identification of such radiation. The realisation that DNA is the site of genetic infonnation in cells subsequently focussed attention on DNA as an important target in the lethal and mutagenic effects of ionising radiation. Thus radiation effects upon DNA became an important area for fundamental scientific studies by radiation biologists, chemists and physicists. To a first approximation, the concerns of the three disciplines can be divided by time scales: the physical process of energy deposition from photon or...
Interest in the biological effects of ionising radiation closely followed the identification of such radiation. The realisation that DNA is the site o...
Summarizing research progress achieved in 32 areas of cell biology covered in this series, this volume places special emphasis on the following topics: recognition in parasitic and symbiotic systems - the molecular biology and genetics of susceptibility and resistance of plants and animals to pathogens, parasites and symbionts - the cell to cell recognition and differentiation - the most challenging problems in developmental biology of plants and animals - the plasticity in cell to cell communication which plays a major role in cell differentiation and function.
Summarizing research progress achieved in 32 areas of cell biology covered in this series, this volume places special emphasis on the following topics...
Presented here are recent findings on bacteriocins: plasmid-encoded toxins produced by bacteria, which differ from traditional antibiotics in killing only bacteria that are closely related to the producing strain. Included are introductory chapters on bacteriocins, microcins (low molecular weight bacteriocins), and lantibiotics (peptide antibiotics containing lanthionine), further, contributions on pore forming bacteriocins, the mechanisms of immunity to bacteriocins, uptake and secretion, as well as evolution of bacteriocins. It is of particular interest that the lantibiotic nisin is...
Presented here are recent findings on bacteriocins: plasmid-encoded toxins produced by bacteria, which differ from traditional antibiotics in killing ...
Immunology is largely a science of observation and experimentation, and these approaches have lead to great increases in our knowledge of the genes, molecules and cells of the immune system. This book is an up-to-date discussion of the current state of modelling and theoretical work in immunology, of the impact of theory on experiment, and of future directions for theoretical research. Among the topics discussed are the function and evolution of the immune system, computer modelling of the humoral immune response and of idiotypic networks and idiotypic mimicry, T-cell memory, cryptic...
Immunology is largely a science of observation and experimentation, and these approaches have lead to great increases in our knowledge of the genes, m...
Nearly every cellular activity, such as cell growth, proliferation, protein synthesis, and nuclear division, is regulated by protein phosphorylation/dephosphorylation on tyrosine residues as initiation events.Synchronization occurs through interaction of protein tyrosine kinases and phosphatases. This book unveils signal pathways that connect extracellular signals with changes of phosphorylation state of target proteins allowing coordinated and integrated modulation of mitogenic signalling. Specifically, cascades involving protein serine/threonine kinases and connections to phosphoinositides...
Nearly every cellular activity, such as cell growth, proliferation, protein synthesis, and nuclear division, is regulated by protein phosphorylation/d...
Although long known as a parasite of medical and veterinary importance, interest in Toxoplasma gondii has increased with its emergence as a major cause of death in immunosuppressed individuals, and with recognition of its suitability as a model system for molecular and cellular investigations of apicomplexan parasites. The NATO workshop brought together 32 scientists working in different areas of toxoplasmosis research to gain an overview of progress in the field. Molecular studies have been carried out on genomic and extrachromosomal DNA. They reveal that Toxoplasma is very highly conserved,...
Although long known as a parasite of medical and veterinary importance, interest in Toxoplasma gondii has increased with its emergence as a major caus...
Combining principles of contemporary immunology with applications to immunopathology, this up-to-date volume documents new developments in the understanding of the origin of autoimmune diseases. Emphasized are cellular and molecular approaches in both organ-specific and systemic autoimmunity. A comprehensive bibliography, numerous illustrations, and tables make it an invaluable source of information for immunologists, rheumatologists, pathologists, dermatologists, and nephrologists.
Combining principles of contemporary immunology with applications to immunopathology, this up-to-date volume documents new developments in the underst...
The Advanced Study Institute on "Structure, Biogenesis and Dynamics of Biological Membranes, held in Cargese from June 14-26, 1993, has been dealing with four major topics in membrane biochemistry today: lipid dynamics and lipid-protein interactions, protein translocation and insertion, intracellular traffic aud protein structure and folding. The lecturers discussed these topics starting from several disciplines, including biochemistry, cell biology, genetics, and biophysics. This wayan interdisciplinary and very inte sting view on biological membrane systems was obtained. At first an...
The Advanced Study Institute on "Structure, Biogenesis and Dynamics of Biological Membranes, held in Cargese from June 14-26, 1993, has been dealing w...
