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This book is published for the researchers to study the stability constant of metal complexes. The determination of formation constants of complexes of some metal ions with ligands have been carried out using Irving Rossotti method in aquesous media at 30 + 0.2o C. Various factors influencing the formation and stabilities of metal complexes are discussed. The overview of coumarin , its derivatives and its metal complexes is given for brief introduction of the work. Different methods are also discussed for the determination of stability constant of metal complexes. The result of pHmetric...

Dr. Kiran S. Nimavat is working in this field since 10 years. She is a Research guide in Chemistry subject in J. J. T. University, Rajasthan. Six students are doing their Ph. D. work under her guidance. She is a member of editorial Board of International Journal of Pharmaceutical Research and Sciences. The area of Interest is Organic, Inorganic and analytical Chemistry. She has published 50 research papers in various national and international journals.

Generally pyrimidine derivatives such as 2-hydroxy-substitutedpyrimidine, 2-mercapto-substituted-pyrimidine and 2-amino-substituted pyrimidine are studied. Pyrimidines have been isolated from the nucleic acid hydrolysates. Pyrimidines are among those molecules that make life possible, have been some of the building blocks of DNA and RNA. Several analogues of pyrimidines have been used as compounds that interfere with the synthesis and functioning of nucleic acids e.g. fluorouracil, which has been used in cancer treatment. Modifications in the base, sugar and phosphate moieties of...

The entire pharma industry is faced with the confront of growing productivity and novelty. The major hurdles are the increasing costs of research and development and a simultaneous stagnating number of new chemical entities. Taking in view of the applicability of heterocyclic compounds, in the present work several entities containing heterocyclic nucleus have been selected.Combinatorial and parallel chemistry are powerful tools for medicinal chemists in drug detection programs. It has expectant chemists to work out synthetic strategies and approaches that can be used for the construction of...