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The actions of many infectious diseases are demanding due to fighting to antimicrobial agents. The emergence of fighting among bacteria to a wide variety of structurally unrelated antibacterial agents such as 6-lactams, macrolides, tetracyclines and fluoroquinolones as well as selected dyes and disinfectants has become a serious public health concern so makes it necessary to continue the search for new antibacterial agents. In recent scenario heterocycles is the different rule in drug synthesis. In that respect pyrimidine plays a significant rule among other heterocycles. From the literature...

The entire pharma industry is faced with the confront of growing productivity and novelty. The major hurdles are the increasing costs of research and development and a simultaneous stagnating number of new chemical entities. Taking in view of the applicability of heterocyclic compounds, in the present work several entities containing heterocyclic nucleus have been selected.Combinatorial and parallel chemistry are powerful tools for medicinal chemists in drug detection programs. It has expectant chemists to work out synthetic strategies and approaches that can be used for the construction of...