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Dr. Kartik B. Vyas M. Sc. , Ph. D.,(Chemistry) F. I. C. C., F. I. C. S. Assistant professor, Sheth L. H. Science College, Mansa, Gujarat(India). Dr. Kartik B. Vyas is working in this field since 15 years. He is a Research guide in Chemistry subject in J. J. T. University, Rajasthan. Six students are doing their Ph. D. work under his guidance. He is a member of editorial Board of International Journal of Pharmaceutical Research and Sciences. The area of Interest is Organic , Inorganic and analytical Chemistry. He has published 60 research papers in various national and international...

Dr. Kiran S. Nimavat is working in this field since 10 years. She is a Research guide in Chemistry subject in J. J. T. University, Rajasthan. Six students are doing their Ph. D. work under her guidance. She is a member of editorial Board of International Journal of Pharmaceutical Research and Sciences. The area of Interest is Organic, Inorganic and analytical Chemistry. She has published 50 research papers in various national and international journals.

The actions of many infectious diseases are demanding due to fighting to antimicrobial agents. The emergence of fighting among bacteria to a wide variety of structurally unrelated antibacterial agents such as 6-lactams, macrolides, tetracyclines and fluoroquinolones as well as selected dyes and disinfectants has become a serious public health concern so makes it necessary to continue the search for new antibacterial agents. In recent scenario heterocycles is the different rule in drug synthesis. In that respect pyrimidine plays a significant rule among other heterocycles. From the literature...

Generally pyrimidine derivatives such as 2-hydroxy-substitutedpyrimidine, 2-mercapto-substituted-pyrimidine and 2-amino-substituted pyrimidine are studied. Pyrimidines have been isolated from the nucleic acid hydrolysates. Pyrimidines are among those molecules that make life possible, have been some of the building blocks of DNA and RNA. Several analogues of pyrimidines have been used as compounds that interfere with the synthesis and functioning of nucleic acids e.g. fluorouracil, which has been used in cancer treatment. Modifications in the base, sugar and phosphate moieties of...